Synergistic Imaging Systems for Enhanced Lesion Diagnosis

Publication ID: 24-11857289_0008_PTD
Published: November 07, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Imaging Systems for Enhanced Lesion Diagnosis,” Published Technical Disclosure No. 24-11857289_0008_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857289_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,289.

Summary of the Inventive Concept

The invention integrates diffuse optical tomography (DOT) with artificial intelligence (AI), Internet of Things (IoT), and blockchain technologies to create a powerful system for optimizing functional images of lesion regions, enabling more accurate diagnoses and personalized treatment.

Background and Problem Solved

The original patent, 'Systems and methods of optimizing functional images of a lesion region using guided diffuse optical tomography,' addressed the limitations of traditional imaging methods in breast cancer diagnosis. However, it did not leverage the potential of AI, IoT, and blockchain to further enhance the accuracy and efficiency of lesion diagnosis. The new inventive concept bridges this gap by integrating these technologies to provide a more comprehensive and secure diagnostic platform.

Detailed Description of the Inventive Concept

The synergistic imaging system consists of a DOT device, an AI module for predictive diagnosis, an IoT-enabled sensor module for environmental factor monitoring, and a blockchain-based data storage module for secure storage and sharing of functional images. The system acquires lesion functional data using the DOT device, transmits it to the AI module for analysis, and generates optimized functional images using the blockchain-based data storage module. The IoT-enabled sensor module integrates environmental factors with the lesion functional data to provide a comprehensive diagnosis. The system can be used for detecting vasculature distribution, assessing malignancy, and reducing biopsies of low-risk benign tumors.

Novelty and Inventive Step

The new inventive concept introduces the synergistic integration of DOT with AI, IoT, and blockchain technologies, which is not obvious from the original patent. The combination of these technologies enables a more accurate, efficient, and secure diagnostic platform, overcoming the limitations of traditional imaging methods.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different AI algorithms, IoT sensor configurations, or blockchain protocols. Variations could also involve the integration of additional technologies, such as machine learning or natural language processing, to further enhance the diagnostic capabilities of the system.

Potential Commercial Applications and Market

The synergistic imaging system has significant commercial potential in the medical imaging industry, particularly in the areas of breast cancer diagnosis, tumor detection, and personalized medicine. The system's ability to provide accurate and secure diagnoses could lead to improved patient outcomes, reduced healthcare costs, and increased market share for companies that adopt this technology.

Field of Art

Medical imaging technologies, specifically diffuse optical tomography (DOT) for diagnostic imaging, requiring advanced knowledge of optical imaging, signal processing, medical diagnostics, and interdisciplinary technology integration

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical imaging specialist with expertise in optical tomography, signal processing algorithms, advanced imaging techniques, and familiarity with emerging technologies like AI and blockchain

Obviousness Rationale

A person having ordinary skill would recognize that integrating AI, IoT, and blockchain technologies with existing DOT imaging systems represents a predictable technological extension that enhances diagnostic capabilities through known interdisciplinary techniques. The fundamental DOT imaging methodology remains consistent with the source patent, while the additional technologies provide incremental improvements in data analysis, storage, and diagnostic precision. These technological integrations would be considered straightforward combinations of known techniques in medical imaging and digital technologies.

Obvious Combinations & Variations

Source Patent Element
DOT device for acquiring lesion functional data with fine and coarse voxel sizes
PTD Variation
Adding AI module for predictive analysis of lesion functional data
Obviousness Reasoning
Applying machine learning algorithms to medical imaging data is a well-established technique for enhancing diagnostic accuracy, representing a predictable technological improvement
Source Patent Element
Functional image optimization methods using matrix transformations
PTD Variation
Blockchain-based secure storage and transmission of functional images
Obviousness Reasoning
Implementing secure, distributed data storage for medical imaging is a known solution for addressing data privacy and integrity challenges in medical technologies
Source Patent Element
Lesion region imaging using diffuse optical tomography
PTD Variation
IoT-enabled sensor module for integrating environmental factor monitoring
Obviousness Reasoning
Expanding diagnostic context by incorporating environmental data represents a logical extension of medical diagnostic methodologies, utilizing standard sensor integration techniques
Source Patent Element
Functional image generation for lesion region analysis
PTD Variation
Machine learning-based malignancy scoring system
Obviousness Reasoning
Developing quantitative diagnostic scoring using AI is a predictable application of machine learning to medical imaging interpretation
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857289 and the published technical disclosure, a person having ordinary skill in medical imaging technologies would find the claimed variations obvious through standard technological integration techniques. The combination of diffuse optical tomography with AI, IoT, and blockchain technologies represents a predictable enhancement of existing medical imaging methodologies, rendering potential patent claims obvious and unpatentable under 35 U.S.C. Section 103.

Original Patent Information

Patent NumberUS 11,857,289
TitleSystems and methods of optimizing functional images of a lesion region using guided diffuse optical tomography
Assignee(s)Washington University