Enhanced Vascular Disease Diagnosis System

Publication ID: 24-11857292_0001_PTD
Published: November 07, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Vascular Disease Diagnosis System,” Published Technical Disclosure No. 24-11857292_0001_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857292_0001_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,292.

Summary of the Inventive Concept

An improved system for diagnosing vascular disease, leveraging advanced machine learning models, personalized synthetic models, and real-time user feedback to enhance accuracy, efficiency, and user experience.

Background and Problem Solved

The original patent disclosed a method for diagnosing vascular disease using geometric feature parameters and fractional flow reserve data. However, this approach has limitations, such as relying on a single synthetic model and lacking personalized diagnosis capabilities. The new inventive concept addresses these limitations by introducing a combination of geometric feature parameters and biometric authentication data, personalized synthetic models, and multiple machine learning models trained on diverse medical imaging data.

Detailed Description of the Inventive Concept

The enhanced vascular disease diagnosis system comprises a processor configured to analyze a combination of geometric feature parameters and biometric authentication data to improve accuracy of diagnosis. The system generates personalized synthetic models based on a patient's medical history to enhance diagnosis efficiency. Additionally, the system includes a database storing multiple machine learning models, each trained on different types of medical imaging data to improve diagnosis accuracy. The system also employs a deep learning algorithm to identify patterns in medical imaging data and predict disease progression. Furthermore, the system features a user interface providing real-time feedback to a user during diagnosis, thereby improving user experience.

Novelty and Inventive Step

The new inventive concept introduces a novel combination of geometric feature parameters and biometric authentication data, as well as personalized synthetic models, which are not disclosed in the original patent. The use of multiple machine learning models trained on diverse medical imaging data and a deep learning algorithm to predict disease progression also represents a significant improvement over the original patent.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include using different types of machine learning algorithms, such as support vector machines or random forests, or incorporating additional data sources, such as electronic health records or wearable device data. Variations of the system could also be designed for specific types of vascular disease or tailored to specific patient populations.

Potential Commercial Applications and Market

The enhanced vascular disease diagnosis system has significant commercial potential in the healthcare industry, particularly in the areas of cardiovascular disease diagnosis and treatment. The system could be marketed to hospitals, clinics, and medical research institutions, and could also be integrated into existing medical imaging systems and electronic health record platforms.

Field of Art

Medical diagnostics, machine learning, and computational medical imaging, with expertise in vascular disease analysis and predictive modeling techniques

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degrees in biomedical engineering, computer science, or medical informatics, possessing expertise in machine learning algorithms, medical image processing, and statistical modeling of physiological data

Obviousness Rationale

A person of ordinary skill would recognize that the PTD represents predictable variations of the source patent's core diagnostic methodology by applying standard machine learning enhancement techniques. The disclosed improvements leverage well-known approaches in medical diagnostics such as personalized modeling, multi-model training, and enhanced user interfaces. These variations represent incremental technical adaptations that would be obvious to a skilled practitioner seeking to improve diagnostic accuracy and system performance.

Obvious Combinations & Variations

Source Patent Element
Generating geometric feature parameter learning data based on synthetic models
PTD Variation
Creating personalized synthetic models based on individual patient medical history
Obviousness Reasoning
Customizing synthetic models for individual patients is a predictable extension of existing synthetic modeling techniques, representing a routine design optimization known in medical machine learning
Source Patent Element
Calculating fractional flow reserve data using computational methods
PTD Variation
Implementing multiple machine learning models trained on diverse medical imaging datasets
Obviousness Reasoning
Using ensemble or multi-model approaches to improve diagnostic accuracy is a standard technique in machine learning, representing an obvious improvement to existing computational diagnostic methods
Source Patent Element
Analyzing stenosis state of blood vessels
PTD Variation
Employing deep learning algorithms to identify patterns and predict disease progression
Obviousness Reasoning
Applying advanced machine learning techniques to medical image analysis represents a predictable technological progression within the field of computational diagnostics
Source Patent Element
Basic vascular disease diagnostic apparatus
PTD Variation
Adding a user interface providing real-time diagnostic feedback
Obviousness Reasoning
Enhancing user experience through interactive interfaces is a standard design improvement that would be obvious to a skilled practitioner seeking to make diagnostic systems more user-friendly
Source Patent Element
Initial machine learning approach for disease diagnosis
PTD Variation
Incorporating biometric authentication data to improve diagnostic accuracy
Obviousness Reasoning
Integrating additional contextual data sources to improve machine learning model performance represents a routine optimization strategy in predictive medical technologies
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857292 and the disclosed technical variations, a person of ordinary skill in the art would find the claimed innovations obvious and lacking inventive step. The published technical disclosure demonstrates that the claimed improvements represent predictable variations achievable through routine design choices and standard machine learning enhancement techniques, thereby rendering subsequent similar claims unpatentable under 35 U.S.C. Section 103.

Original Patent Information

Patent NumberUS 11,857,292
TitleMethod for diagnosing vascular disease and apparatus therefor
Assignee(s)E8IGHT Co., Ltd.