Enhanced Method and System for Determining Patient Volume Responsiveness

Publication ID: 24-11857302_0001_PTD
Published: November 07, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Method and System for Determining Patient Volume Responsiveness,” Published Technical Disclosure No. 24-11857302_0001_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857302_0001_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,302.

Summary of the Inventive Concept

An improved method and system for determining a parameter representative for a patient's volume responsiveness, enhancing accuracy and efficiency through advanced signal processing techniques and machine learning algorithms.

Background and Problem Solved

The original patent disclosed a method and system for determining volume responsiveness, but limitations existed in terms of signal noise and processing complexity. The new inventive concept addresses these limitations by introducing advanced signal processing techniques, such as low-pass filtering, wavelet transforms, and Gaussian filtering, to improve the accuracy and efficiency of volume responsiveness determination.

Detailed Description of the Inventive Concept

The enhanced method and system comprise a pulse signal measurement unit, a processing unit, and a logic unit. The processing unit applies advanced signal processing techniques to the measured pulse signals, including low-pass filtering, wavelet transforms, and Gaussian filtering, to determine an envelope signal curve. The logic unit then determines a volume responsiveness indicator based on the envelope signal curve. Additionally, machine learning algorithms can be employed to improve the accuracy of the volume responsiveness determination. The system can be integrated with various pulse signal measurement methods, including oscillometric non-invasive blood pressure measurement and photoplethysmography (PPG) sensors.

Novelty and Inventive Step

The new claims introduce novel signal processing techniques and machine learning algorithms that significantly improve the accuracy and efficiency of volume responsiveness determination compared to the original patent. The inventive step lies in the application of these advanced techniques to the specific problem of volume responsiveness determination, providing a non-obvious solution that enhances the original patent's functionality.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different signal processing techniques, such as Fourier transforms or machine learning algorithms, to determine the envelope signal curve. Additionally, the system could be integrated with various medical devices, such as patient monitors or ventilators, to provide a more comprehensive solution for volume responsiveness determination.

Potential Commercial Applications and Market

The enhanced method and system for determining patient volume responsiveness have significant commercial potential in the medical device industry, particularly in the fields of critical care, anesthesia, and cardiology. The inventive concept could be integrated into various medical devices, providing a competitive advantage in terms of accuracy and efficiency. The target market includes hospitals, clinics, and medical research institutions.

Field of Art

Medical signal processing and patient monitoring, specifically focused on physiological parameter analysis and volume responsiveness determination using non-invasive measurement techniques

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device researcher with expertise in signal processing, physiological monitoring, machine learning, and medical sensor technologies, holding at least a master's degree with 3-5 years of experience in medical device development

Obviousness Rationale

A PHOSITA would recognize that the PTD's variations represent standard signal processing techniques and machine learning approaches that are commonly applied to physiological signal analysis. The core method of volume responsiveness determination remains fundamentally unchanged, with the PTD merely introducing well-known signal enhancement and computational techniques that would be predictable extensions of the original patent's methodology.

Obvious Combinations & Variations

Source Patent Element
Oscillometric non-invasive pulse measurement method for detecting patient pulse signals
PTD Variation
Extending measurement techniques to include photoplethysmography (PPG) sensors and applying additional signal processing filters
Obviousness Reasoning
A PHOSITA would recognize that different non-invasive pulse measurement techniques are interchangeable, and signal processing filters are standard methods for improving signal quality in physiological monitoring
Source Patent Element
Basic pulse signal analysis for determining volume responsiveness
PTD Variation
Introducing machine learning algorithms and advanced signal processing techniques like wavelet transforms and Gaussian filtering
Obviousness Reasoning
Machine learning and advanced signal processing are known techniques for enhancing signal analysis, representing a predictable improvement that would be obvious to implement in medical signal processing
Source Patent Element
Respiratory cycle-based pulse signal measurement
PTD Variation
Implementing low-pass filtering and envelope signal curve determination using multiple computational approaches
Obviousness Reasoning
Signal envelope extraction and filtering are standard signal processing techniques that would be considered routine design choices for improving physiological signal analysis
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857302 and the disclosed variations, a person of ordinary skill in the art would find the claimed innovations obvious, as they represent predictable applications of known signal processing and machine learning techniques to the established method of determining patient volume responsiveness. The variations constitute routine engineering modifications that do not rise to the level of non-obvious innovation.

Original Patent Information

Patent NumberUS 11,857,302
TitleMethod, logic unit and system for determining a parameter representative for the patient's volume responsiveness
Assignee(s)PHILIPS MEDIZIN SYSTEME BĂ–BLINGEN GMBH