Enhanced Method and System for Determining Patient Volume Responsiveness

Publication ID: 24-11857302_0006_PTD
Published: November 07, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Method and System for Determining Patient Volume Responsiveness,” Published Technical Disclosure No. 24-11857302_0006_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857302_0006_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,302.

Summary of the Inventive Concept

An improved method and system for determining a patient's volume responsiveness, providing more accurate and efficient fluid management through advanced signal processing and machine learning techniques.

Background and Problem Solved

The original patent disclosed a method and system for determining a patient's volume responsiveness. However, it had limitations in terms of signal processing and accuracy. The new inventive concept addresses these limitations by introducing advanced signal processing techniques, machine learning algorithms, and real-time monitoring capabilities, enabling more accurate and efficient fluid management.

Detailed Description of the Inventive Concept

The new inventive concept comprises a system with a pulse signal analyzer, a processor, and a display unit. The pulse signal analyzer detects pulse signals of a patient over multiple respiratory cycles. The processor determines an indicator representative of the patient's volume responsiveness using advanced signal processing techniques, such as non-negative smooth bell-shaped curves or Cauchy-Lorentz functions. The system also incorporates machine learning algorithms to predict a patient's volume responsiveness based on collected datasets. The display unit provides real-time monitoring of the determined indicator. Additionally, the system can be trained using a dataset of pulse signals and corresponding volume responsiveness indicators for multiple patients.

Novelty and Inventive Step

The new inventive concept introduces advanced signal processing techniques, machine learning algorithms, and real-time monitoring capabilities, which are not present in the original patent. These features provide more accurate and efficient fluid management, making the new inventive concept novel and non-obvious.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include using different signal processing techniques, such as wavelet analysis or Fourier transform, or incorporating additional physiological parameters, such as blood pressure or oxygen saturation, to improve the accuracy of volume responsiveness determination. Variations could also include using different machine learning algorithms or training datasets to adapt the system to specific patient populations or medical conditions.

Potential Commercial Applications and Market

The enhanced method and system for determining patient volume responsiveness have significant commercial potential in the medical device industry, particularly in critical care and anesthesia. The system could be integrated into existing patient monitoring systems, providing a competitive advantage in terms of accuracy and efficiency. The market potential is substantial, with an estimated global market size of over $1 billion by 2025.

Field of Art

Medical signal processing and patient monitoring systems, specifically focused on physiological parameter analysis and volume responsiveness determination using non-invasive pulse measurement techniques

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device specialist with expertise in signal processing, machine learning, physiological monitoring, and medical data analysis, holding advanced degrees in biomedical engineering or related fields

Obviousness Rationale

A person having ordinary skill in the art would recognize that the PTD's disclosed variations represent predictable extensions of the source patent's core methodology for volume responsiveness determination, utilizing standard signal processing techniques and machine learning approaches that are well-established in medical monitoring technology.

Obvious Combinations & Variations

Source Patent Element
Oscillometric non-invasive pulse measurement method for detecting patient pulse signals across respiratory cycles
PTD Variation
Incorporation of machine learning algorithms to predict volume responsiveness based on collected pulse signal datasets
Obviousness Reasoning
Applying machine learning to existing signal processing techniques is a known approach for enhancing medical diagnostic methods, representing a predictable optimization of the original patent's methodology
Source Patent Element
Signal fit functions using non-negative smooth bell-shaped curves or Cauchy-Lorentz functions
PTD Variation
Extending signal processing techniques to include alternative methods like wavelet analysis or Fourier transform
Obviousness Reasoning
A skilled practitioner would recognize multiple equivalent signal processing techniques as interchangeable design choices for analyzing physiological signals
Source Patent Element
Pulse signal detection across multiple respiratory cycles
PTD Variation
Real-time monitoring display and dynamic adjustment of volume responsiveness indicators
Obviousness Reasoning
Implementing real-time visualization and dynamic parameter adjustment represents a standard enhancement in medical monitoring systems, motivated by improving clinical utility
Source Patent Element
Method for determining patient volume responsiveness indicator
PTD Variation
Incorporating additional physiological parameters like blood pressure and oxygen saturation to improve accuracy
Obviousness Reasoning
Integrating multiple physiological metrics to enhance diagnostic precision is a routine approach in medical signal processing and monitoring technologies
Source Patent Element
Patient pulse signal analysis method
PTD Variation
Patient-specific parameter adaptation in signal processing algorithms
Obviousness Reasoning
Customizing diagnostic algorithms to individual patient characteristics is a predictable evolution in personalized medical monitoring technologies
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857302, a person having ordinary skill in the art would find the technical variations disclosed herein to be obvious extensions of the prior art, representing predictable combinations of known signal processing techniques, machine learning approaches, and medical monitoring methodologies that would be readily conceived by a skilled practitioner in the field of physiological parameter analysis.

Original Patent Information

Patent NumberUS 11,857,302
TitleMethod, logic unit and system for determining a parameter representative for the patient's volume responsiveness
Assignee(s)PHILIPS MEDIZIN SYSTEME BĂ–BLINGEN GMBH