Concurrent MRSI and fMRI for Industrial and Environmental Applications

Publication ID: 24-11857306_0007_PTD
Published: November 07, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Concurrent MRSI and fMRI for Industrial and Environmental Applications,” Published Technical Disclosure No. 24-11857306_0007_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857306_0007_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,306.

Summary of the Inventive Concept

This inventive concept applies the core technology of concurrent MRSI and fMRI to various industrial and environmental applications, enabling real-time monitoring and analysis of water quality, agricultural irrigation systems, chemical reactions, commercial water usage, and aquatic ecosystems.

Background and Problem Solved

The original patent addressed the limitations of MRSI and fMRI in the clinical setting, but the technology has broader applications. The new inventive concept solves the problem of inefficient monitoring and analysis in various industrial and environmental sectors by leveraging the concurrent acquisition of MRSI and fMRI data.

Detailed Description of the Inventive Concept

The inventive concept comprises an MRI scanner and an electronic processor configured to concurrently acquire MRSI and fMRI data of water samples or reaction mixtures. The MRSI data is analyzed to detect contaminants, changes in water composition, or reaction intermediates, while the fMRI data is used to monitor water flow patterns, reaction kinetics, or aquatic ecosystem dynamics. The system enables real-time monitoring, automated analysis, and data-driven decision-making in various industries.

Novelty and Inventive Step

The new inventive concept is novel and non-obvious in its application of concurrent MRSI and fMRI to industrial and environmental sectors, which was not considered in the original patent. The inventive step lies in the adaptation of the core technology to address specific challenges in these sectors.

Alternative Embodiments and Variations

Alternative embodiments may include using different MRI scanner configurations, modifying the electronic processor's algorithms, or integrating additional sensors to enhance data accuracy. Variations may include applying the technology to other industries, such as oil and gas or pharmaceuticals.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in various industries, including water treatment, agriculture, chemical manufacturing, commercial real estate, and environmental monitoring. The target market includes companies and organizations seeking to improve operational efficiency, reduce costs, and enhance environmental sustainability.

Field of Art

Medical Imaging and Spectroscopic Analysis, with expertise in Magnetic Resonance Imaging (MRI) techniques, spectroscopic data acquisition, and multi-modal imaging systems

Person of Ordinary Skill (PHOSITA) Profile

A skilled practitioner with advanced degrees in biomedical engineering or medical physics, experienced in MRI technology, signal processing, and interdisciplinary application of imaging techniques across different domains

Obviousness Rationale

The PTD represents a straightforward extension of the source patent's core technology by applying concurrent MRSI and fMRI techniques to industrial and environmental monitoring contexts. A PHOSITA would recognize that the fundamental MRI scanning and data processing principles remain consistent across different application domains. The technical adaptations primarily involve reconfiguring the electronic processor's analysis algorithms and targeting different sample types, which would be considered routine engineering modifications.

Obvious Combinations & Variations

Source Patent Element
Concurrent acquisition of MRSI and fMRI data using an MRI scanner
PTD Variation
Applying the concurrent imaging technique to water samples and industrial processes
Obviousness Reasoning
Extending imaging techniques to new domains is a predictable application of known technological principles, representing a simple substitution of sample types with expected results
Source Patent Element
Electronic processor configured to analyze metabolite signals and water readout modules
PTD Variation
Modifying processor algorithms to detect contaminants and monitor water flow patterns
Obviousness Reasoning
Signal processing and data analysis techniques are transferable across domains, with algorithm modifications representing standard engineering design choices
Source Patent Element
Method of quantifying metabolite concentrations based on spectroscopic signals
PTD Variation
Detecting chemical composition changes in industrial water samples and reaction mixtures
Obviousness Reasoning
Spectroscopic analysis principles remain consistent, with the primary change being the specific chemical context of analysis
Source Patent Element
MRI scanner capable of simultaneous multi-modal data acquisition
PTD Variation
Adapting the scanner configuration for industrial and environmental monitoring applications
Obviousness Reasoning
Hardware adaptations for different sample types represent predictable engineering modifications within a known technological framework
35 U.S.C. § 103 Summary: Pursuant to 35 U.S.C. ยง 103, the variations disclosed in the Published Technical Disclosure would have been obvious to a Person Having Ordinary Skill In The Art at the time of invention, based on the teachings of US Patent 11857306. The PTD demonstrates that the core technological principles of concurrent MRSI and fMRI can be readily adapted to alternative domains through routine engineering modifications, thereby rendering potential patent claims in these areas anticipated and non-patentable.

Original Patent Information

Patent NumberUS 11,857,306
TitleConcurrent MRSI and fMRI
Assignee(s)UNM RAINFOREST INNOVATIONS