Next-Generation Concurrent MRSI and fMRI

Publication ID: 24-11857306_0010_PTD
Published: November 07, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Next-Generation Concurrent MRSI and fMRI,” Published Technical Disclosure No. 24-11857306_0010_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857306_0010_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,306.

Summary of the Inventive Concept

A revolutionary system for real-time, concurrent Magnetic Resonance Spectroscopic Imaging (MRSI) and functional Magnetic Resonance Imaging (fMRI) data acquisition, leveraging advanced AI and machine learning algorithms to provide high-resolution, multi-parametric maps of brain function and metabolism.

Background and Problem Solved

The original patent, 'Concurrent MRSI and fMRI,' addressed the limitations of traditional MRSI and fMRI scans, which are time-consuming and often preclude collecting data concurrently. However, the next-generation system envisions a more ambitious and forward-thinking approach, integrating AI-assisted adaptive water suppression, machine learning-based reconstruction, and real-time data analysis to overcome the limitations of the original patent.

Detailed Description of the Inventive Concept

The next-generation system comprises a hybrid MRI scanner capable of simultaneously capturing spatially-encoded water and metabolite signals. The machine learning-based processor instantaneously reconstructs and correlates the MRSI and fMRI data, generating high-resolution, multi-parametric maps of brain function and metabolism. The system also integrates advanced neural network algorithms to predict and diagnose neurological disorders, and can be used for real-time, intra-operative guidance during neurosurgical procedures.

Novelty and Inventive Step

The new claims introduce a paradigm shift in MRSI and fMRI technology, leveraging AI and machine learning to enable real-time, concurrent data acquisition and analysis. The inventive step lies in the integration of these advanced algorithms with the hybrid MRI scanner, providing a previously unknown level of precision, speed, and functionality.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of wearable, MRI-compatible headsets for non-invasive, in-vivo monitoring of brain metabolism and function. Variations could also involve the development of cloud-based platforms for data storage and analysis, or the integration of the system with other medical imaging modalities.

Potential Commercial Applications and Market

The next-generation concurrent MRSI and fMRI system has significant commercial potential in the medical imaging and diagnostics industries, with potential applications in neurology, oncology, and psychiatry. The system could also be used in research settings to advance our understanding of brain function and metabolism.

Original Patent Information

Patent NumberUS 11,857,306
TitleConcurrent MRSI and fMRI
Assignee(s)UNM RAINFOREST INNOVATIONS