Enhanced System for Accurate Localization of Cardiac Arrythmia Origins

Publication ID: 24-11857307_0006_PTD
Published: November 07, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced System for Accurate Localization of Cardiac Arrythmia Origins,” Published Technical Disclosure No. 24-11857307_0006_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857307_0006_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,307.

Summary of the Inventive Concept

An improved system for finding the origin of a single-source arrythmia, utilizing advanced mapping, LAT-derived distance calculations, and real-time probe adjustments to provide more accurate and efficient localization.

Background and Problem Solved

The original patent disclosed a method for finding the origin of an arrythmia, but it had limitations in terms of accuracy and efficiency. The new inventive concept addresses these limitations by introducing advanced mapping and LAT-derived distance calculations, enabling more precise localization of the arrythmia origin.

Detailed Description of the Inventive Concept

The enhanced system comprises a mapping module to generate a detailed map of the heart chamber where the single-source arrythmia is present. A processing module calculates local activation times (LATs) over the surface of the chamber and determines the origin of the arrythmia based on LAT-derived distances from at least two pairs of points on the surface. The system can also incorporate machine learning algorithms to optimize the origin location. Additionally, the probe is adapted to adjust its position in real-time based on the calculated origin location, ensuring more accurate and efficient localization.

Novelty and Inventive Step

The new inventive concept introduces the use of advanced mapping, LAT-derived distance calculations, and real-time probe adjustments, which are not present in the original patent. These features provide a more accurate and efficient method for localizing the origin of a single-source arrythmia.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different mapping modalities, such as MRI or CT scans, or the integration of additional sensors to provide more accurate LAT measurements. Variations of the system could also be designed for use in different heart chambers or for localizing origins of other types of arrythmias.

Potential Commercial Applications and Market

The enhanced system for localizing cardiac arrythmia origins has significant commercial potential in the medical device industry, particularly in the field of cardiac electrophysiology. The system could be marketed to hospitals and medical centers, providing a more accurate and efficient method for treating cardiac arrythmias.

Field of Art

Cardiac electrophysiology and medical device technologies for cardiac mapping and arrythmia localization, requiring advanced knowledge of electrical signal processing, medical imaging, and interventional cardiology techniques

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or clinical electrophysiologist with expertise in cardiac mapping technologies, signal processing algorithms, medical device design, and advanced diagnostic imaging techniques

Obviousness Rationale

A person having ordinary skill in the art would recognize that the PTD's disclosed variations represent predictable extensions of the source patent's fundamental approach to cardiac arrythmia localization. The core methodology of using local activation times (LATs) and electrode-based mapping remains consistent, with the PTD introducing incremental improvements in computational techniques and probe positioning that would be considered routine optimization by a skilled practitioner.

Obvious Combinations & Variations

Source Patent Element
Probe with multiple electrode pairs for generating location signals in a heart chamber
PTD Variation
Adding real-time probe position adjustment based on calculated arrythmia origin
Obviousness Reasoning
A PHOSITA would recognize that dynamic probe repositioning is a predictable enhancement to improve mapping accuracy, representing a standard design optimization in medical imaging technologies
Source Patent Element
Calculating conduction velocity using LAT-derived distances between points
PTD Variation
Incorporating machine learning algorithms to optimize origin location calculation
Obviousness Reasoning
Applying machine learning to signal processing is a known technique in medical diagnostics, representing an obvious improvement to existing computational methods for signal analysis
Source Patent Element
Locating single-source arrythmia origin using electrode-based mapping
PTD Variation
Introducing weighted LAT-derived distance calculations based on point proximity
Obviousness Reasoning
Implementing weighted distance calculations is a standard signal processing technique that would be obvious to a skilled practitioner seeking to improve localization precision
Source Patent Element
Basic cardiac chamber mapping technique
PTD Variation
Expanding mapping modalities to include MRI and CT scan integration
Obviousness Reasoning
Utilizing multiple imaging modalities is a predictable design choice for improving diagnostic accuracy, representing a standard approach in medical imaging technologies
Source Patent Element
Two-dimensional arrythmia origin mapping
PTD Variation
Adding 3D visualization with confidence level indicators
Obviousness Reasoning
Enhanced visualization techniques are a routine improvement in medical diagnostic technologies, representing an obvious extension of existing mapping methodologies
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857307 and the disclosed technical variations, a person having ordinary skill in the art would find the claimed innovations obvious and lacking inventive step. The incremental improvements in cardiac arrythmia localization techniques represent predictable variations that would be readily conceived by a skilled practitioner without requiring extraordinary insight or non-obvious problem-solving.

Original Patent Information

Patent NumberUS 11,857,307
TitleFinding the origin of an arrythmia
Assignee(s)Rutgers, The State University of New Jersey, Biosense Webster (Israel) Ltd.