Synergistic Sweat Biosensing Systems

Publication ID: 24-11857313_0003_PTD
Published: November 07, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Sweat Biosensing Systems,” Published Technical Disclosure No. 24-11857313_0003_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857313_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,313.

Summary of the Inventive Concept

Integrating sweat biosensing technology with distinct technologies such as AI, IoT, blockchain, and new materials to create a more powerful system for personalized health monitoring and disease diagnosis.

Background and Problem Solved

The original sweat biosensing patent provided a non-invasive means of monitoring biomarkers in sweat. However, its limitations in data analysis, security, and real-time monitoring were addressed by synergistically combining it with other technologies. This new inventive concept solves the problem of isolated biosensing by integrating it with AI for personalized health recommendations, IoT for real-time monitoring, blockchain for secure data storage, and new materials for enhanced sensitivity and selectivity.

Detailed Description of the Inventive Concept

The synergistic sweat biosensing system comprises a sweat biosensor, an AI module, an IoT module, a blockchain module, and a novel material-based sensor. The sweat biosensor detects analytes in sweat, which are then analyzed by the AI module to provide personalized health recommendations. The IoT module transmits the detected analytes to a remote server for real-time monitoring. The blockchain module securely stores the data on a decentralized network. The novel material-based sensor enhances the sensitivity and selectivity of the sweat biosensor. The system enables continuous, simultaneous, and secure monitoring of biomarkers in sweat, providing a more comprehensive understanding of an individual's health status.

Novelty and Inventive Step

The new claims introduce a synergistic combination of sweat biosensing with AI, IoT, blockchain, and new materials, which is not obvious from the original patent. The inventive step lies in the integration of these distinct technologies to create a more powerful system for personalized health monitoring and disease diagnosis.

Alternative Embodiments and Variations

Alternative embodiments of the synergistic sweat biosensing system could include integrating it with machine learning algorithms for predicting health outcomes, using different types of sensors or materials, or incorporating additional data sources such as environmental or wearable device data. Variations could include developing specific systems for particular applications, such as athletic performance monitoring or neonatal health monitoring.

Potential Commercial Applications and Market

The synergistic sweat biosensing system has significant commercial potential in various industries, including personal digital health, athletics, neonatology, and pharmacological monitoring. The market for wearable devices and health monitoring systems is growing rapidly, and this inventive concept could capture a significant share of that market by providing a more comprehensive and personalized health monitoring solution.

Field of Art

Biomedical sensing technologies, specifically non-invasive biosensing systems for health monitoring, requiring advanced knowledge in sensor design, signal processing, data analytics, and interdisciplinary technology integration

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or technical professional with expertise in biosensors, signal processing, data analytics, and emerging digital health technologies, holding advanced degrees in bioengineering, electrical engineering, or related fields

Obviousness Rationale

A PHOSITA would recognize that integrating sweat biosensing with emerging digital technologies like AI, IoT, and blockchain represents a predictable combination of known techniques in personalized health monitoring. The source patent establishes the foundational biosensing methodology, while the PTD demonstrates straightforward technological extensions using standard integration approaches common in digital health innovation.

Obvious Combinations & Variations

Source Patent Element
Method of sensing multiple analytes simultaneously in different biofluids
PTD Variation
Adding AI analysis module to interpret and generate personalized health recommendations from biosensing data
Obviousness Reasoning
Applying machine learning to biosensor data is a known technique for extracting predictive insights, representing an obvious design choice for enhancing diagnostic capabilities
Source Patent Element
Continuous biosensing of analytes in sweat
PTD Variation
Incorporating IoT transmission for real-time remote monitoring of biosensing data
Obviousness Reasoning
Extending biosensor data transmission via IoT technologies is a predictable solution for enabling continuous health monitoring, utilizing standard communication protocols
Source Patent Element
Biosensing method for detecting multiple analytes
PTD Variation
Implementing blockchain for secure, decentralized storage of biosensing data
Obviousness Reasoning
Using blockchain for secure medical data storage represents an obvious technological enhancement addressing known data privacy challenges in digital health
Source Patent Element
Sweat biosensing device with multiple sensor configurations
PTD Variation
Developing novel material-based sensors with enhanced sensitivity and selectivity
Obviousness Reasoning
Exploring advanced materials to improve sensor performance is a standard engineering approach for incremental technological improvement
35 U.S.C. § 103 Summary: Based on US Patent 11857313's foundational sweat biosensing methodology, the present publication demonstrates that integrating biosensing technologies with AI, IoT, blockchain, and advanced materials represents an obvious technological progression that would be readily conceived by a person having ordinary skill in biomedical sensing technologies, thereby establishing prior art that anticipates similar technological combinations.

Original Patent Information

Patent NumberUS 11,857,313
TitleSweat biosensing companion devices and subsystems
Assignee(s)University of Cincinnati