Intelligent Cardiovascular Disease Diagnosis and Monitoring System

Publication ID: 24-11857318_0003_PTD
Published: November 07, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Intelligent Cardiovascular Disease Diagnosis and Monitoring System,” Published Technical Disclosure No. 24-11857318_0003_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857318_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,318.

Summary of the Inventive Concept

A novel system integrating electrochemical impedance spectroscopy with AI, IoT, blockchain, and nanomaterials for accurate cardiovascular disease diagnosis, monitoring, and personalized health recommendations.

Background and Problem Solved

The original patent addressed the limitations of conventional plaque rupture detection methods, but it lacked the integration of advanced technologies to enhance its capabilities. The new inventive concept overcomes this limitation by combining electrochemical impedance spectroscopy with AI, IoT, blockchain, and nanomaterials to provide a comprehensive and accurate cardiovascular disease diagnosis and monitoring system.

Detailed Description of the Inventive Concept

The system comprises a tissue sensing device (as described in the original patent) that collects electrical impedance spectroscopy data, which is then transmitted to a cloud-based IoT platform for analysis using artificial intelligence algorithms. The system also incorporates a machine learning module trained on a dataset of plaque rupture events, a blockchain-based data storage system for securely storing and sharing patient data, and a nanomaterial-based contrast agent for enhancing ultrasound imaging. The system's components work synergistically to identify high-risk atherosclerotic lesions, detect metabolically active lesions, and provide personalized health recommendations.

Novelty and Inventive Step

The new inventive concept's novelty lies in the integration of electrochemical impedance spectroscopy with AI, IoT, blockchain, and nanomaterials, which enables accurate cardiovascular disease diagnosis, monitoring, and personalized health recommendations. The inventive step is the synergistic combination of these distinct technologies to create a more powerful system.

Alternative Embodiments and Variations

Alternative embodiments may include using different types of sensors or imaging modalities, integrating with other healthcare systems or wearables, or applying the system to other disease diagnosis and monitoring applications.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the healthcare industry, particularly in the areas of cardiovascular disease diagnosis and monitoring. The system's ability to provide accurate and personalized health recommendations can lead to improved patient outcomes, reduced healthcare costs, and increased market share for companies adopting this technology.

Original Patent Information

Patent NumberUS 11,857,318
TitleElectrochemical impedance spectroscopy
Assignee(s)The Regents of the University of California