Intelligent Blood Sequestration System for Real-Time Microbial Infection Detection and Personalized Treatment
Legal Citation
Summary of the Inventive Concept
A next-generation blood sequestration device integrating microfluidic, biosensor, data analytics, and artificial intelligence technologies to enable real-time microbial infection detection, personalized treatment, and remote monitoring, revolutionizing blood culture analysis and patient care.
Background and Problem Solved
The original blood sequestration device patent ( Blood sequestration device and method ) addressed the need for safe and efficient blood sampling. However, it lacked the capability to detect microbial infections in real-time, relied on manual analysis, and did not provide personalized treatment recommendations. The new inventive concept addresses these limitations by incorporating advanced technologies to provide a more comprehensive and efficient solution.
Detailed Description of the Inventive Concept
The intelligent blood sequestration system consists of a microfluidic module for real-time microbial infection detection, a biosensor for detecting biomarkers, a data analytics module for predicting patient outcomes and suggesting personalized treatment regimens, and an artificial intelligence module for adapting to changing patient conditions and optimizing blood culture analysis. The system can be integrated with a cloud-based platform and mobile application for remote monitoring and real-time updates.
Novelty and Inventive Step
The new inventive concept's integration of microfluidic, biosensor, data analytics, and artificial intelligence technologies enables real-time microbial infection detection, personalized treatment, and remote monitoring, which is not taught by the original patent. The incorporation of these advanced technologies provides a novel and non-obvious solution that significantly improves blood culture analysis and patient care.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include the use of different biosensor technologies, such as nano-particle based sensors or graphene-based sensors, or the integration of genomic analysis for personalized medicine. Variations could also include the development of a handheld device for point-of-care testing or a decentralized system for remote monitoring and analysis.
Potential Commercial Applications and Market
The intelligent blood sequestration system has significant commercial potential in the healthcare industry, particularly in the areas of infectious disease diagnosis and personalized medicine. The system could be marketed to hospitals, clinics, and research institutions, and could also be used in decentralized healthcare settings, such as telemedicine platforms and remote patient monitoring services.
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Medical device engineering, specifically blood collection and diagnostic technologies, focusing on microfluidic systems and medical instrumentation for infection detection
Person of Ordinary Skill (PHOSITA) Profile
A biomedical engineer or medical device designer with expertise in blood collection technologies, microfluidic systems, biosensor design, and clinical diagnostic instrumentation, holding at least a master's degree with 3-5 years of industry experience
Obviousness Rationale
A person of ordinary skill would recognize that the source patent's blood sequestration device provides a fundamental technical foundation that can be naturally extended through integration of contemporary diagnostic technologies. The PTD's additions of microfluidic modules, biosensors, and data analytics represent predictable technological improvements that would be obvious to implement given the existing blood collection device framework. The core mechanical sequestration mechanism remains fundamentally consistent, with the novel elements representing incremental enhancements to diagnostic capabilities.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,320 |
|---|---|
| Title | Blood sequestration device and method |
| Assignee(s) | Smiths Medical ASD, Inc. |