Enhanced Systems and Methods for Mental Health Diagnosis and Treatment

Publication ID: 24-11857322_0001_PTD
Published: November 07, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Systems and Methods for Mental Health Diagnosis and Treatment,” Published Technical Disclosure No. 24-11857322_0001_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857322_0001_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,322.

Summary of the Inventive Concept

An advanced system for evaluating, diagnosing, and stratifying patients with mental health issues, providing accurate probability scores, confidence levels, and personalized treatment plans.

Background and Problem Solved

The original patent disclosed systems and methods for screening, diagnosing, and stratifying patients with neuropsychiatric diseases. However, these systems lacked the ability to provide accurate probability scores, confidence levels, and personalized treatment plans. The present inventive concept addresses these limitations by introducing enhanced systems and methods that improve the accuracy and effectiveness of mental health diagnosis and treatment.

Detailed Description of the Inventive Concept

The new inventive concept comprises systems and methods that integrate advanced machine learning algorithms, Bayesian Decision Lists, and cognitive task outcome measures to provide accurate probability scores and confidence levels for mental health conditions. The systems can output mental health conditions with a probability score of accuracy, recommend personalized treatment plans based on the patient's medical history, identify potential biomarkers, and track the progress of a patient's mental health condition in real-time. The methods involve receiving input features from patients, applying Bayesian Decision Lists, and outputting mental health conditions with confidence levels.

Novelty and Inventive Step

The new claims introduce the concept of probability scores, confidence levels, and personalized treatment plans, which are not present in the original patent. The use of Bayesian Decision Lists and cognitive task outcome measures to improve the accuracy of mental health diagnosis is also novel and non-obvious.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different machine learning algorithms, additional input features, or integration with wearable devices and electronic health records. Variations could include systems for diagnosing specific mental health conditions, such as bi-polar disorder or PTSD.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the mental health industry, with applications in healthcare providers, pharmaceutical companies, and research institutions. The market for mental health diagnosis and treatment is growing rapidly, and the present inventive concept is well-positioned to capture a significant share of this market.

Field of Art

Mental health diagnostics, machine learning, and computational medical assessment systems, with expertise in probabilistic modeling, cognitive task analysis, and patient screening technologies

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degrees in computer science, biomedical engineering, or clinical informatics, possessing expertise in machine learning algorithms, statistical modeling, and healthcare data processing techniques

Obviousness Rationale

A PHOSITA would recognize that extending the source patent's mental health diagnostic system with probability scoring, confidence levels, and personalized treatment recommendations represents a predictable enhancement using standard machine learning and statistical techniques. The core diagnostic framework remains consistent, with the PTD introducing incremental improvements in quantification and personalization of diagnostic outputs. These variations would be considered obvious improvements within the existing technological paradigm of computational medical diagnostics.

Obvious Combinations & Variations

Source Patent Element
Bayesian Decision List for mental health condition evaluation
PTD Variation
Adding probability scores and confidence levels to Bayesian Decision List outputs
Obviousness Reasoning
Quantifying probabilistic outputs is a standard technique in machine learning, representing a predictable design choice for improving diagnostic precision
Source Patent Element
System for identifying mental health conditions using input features
PTD Variation
Recommending personalized treatment plans based on diagnostic results and patient history
Obviousness Reasoning
Integrating diagnostic results with treatment recommendations is a logical extension of clinical decision support systems, representing a known technique in medical informatics
Source Patent Element
Cognitive task outcome measures as input features
PTD Variation
Real-time tracking and feedback mechanisms for patient mental health progress
Obviousness Reasoning
Continuous monitoring and feedback are standard approaches in digital health technologies, representing a predictable evolution of diagnostic systems
Source Patent Element
Mental health condition identification system
PTD Variation
Identifying potential biomarkers associated with diagnosed conditions
Obviousness Reasoning
Expanding diagnostic systems to include biomarker identification is a foreseeable advancement in precision medicine and computational diagnostics
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857322 and the published technical disclosure, a person of ordinary skill in the art would find the claimed variations obvious, as they represent predictable extensions of existing mental health diagnostic technologies through standard machine learning and clinical informatics techniques. The disclosed system modifications constitute obvious combinations that would be readily apparent to a skilled practitioner without requiring inventive insight.

Original Patent Information

Patent NumberUS 11,857,322
TitleSystems and methods for screening, diagnosing, and stratifying patients
Assignee(s)Neumora Therapeutics, Inc.