Intelligent Agent-Delivering Neural Probe Systems

Publication ID: 24-11857326_0003_PTD
Published: November 07, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Intelligent Agent-Delivering Neural Probe Systems,” Published Technical Disclosure No. 24-11857326_0003_PTD, Published November 07, 2025, available at https://archive.pr1or.art/24-11857326_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,326.

Summary of the Inventive Concept

This inventive concept integrates advanced technologies like AI, IoT, blockchain, and novel biomaterials with agent-delivering neural probes to create a more powerful system for neural stimulation and treatment.

Background and Problem Solved

Known neural probes have limitations in terms of damage to brain tissue, limited treatment agent delivery, and inadequate data tracking. This inventive concept addresses these limitations by incorporating synergistic technologies to enhance the functionality and efficacy of agent-delivering neural probes.

Detailed Description of the Inventive Concept

The inventive concept comprises a neural probe device with integrated AI-powered agent delivery systems, IoT-enabled sensors for real-time brain activity monitoring, blockchain-based secure data storage, and novel biomaterial coatings for enhanced agent delivery. The AI-powered system optimizes agent delivery based on patient-specific data, while the IoT-enabled sensor provides real-time feedback for personalized therapy. The blockchain-based data storage system ensures secure and transparent tracking of agent delivery and stimulation data.

Novelty and Inventive Step

The inventive concept's novelty lies in the synergistic integration of AI, IoT, blockchain, and novel biomaterials with agent-delivering neural probes, providing a more powerful system for neural stimulation and treatment. The inventive step is the combination of these distinct technologies to create a system that is more than the sum of its parts.

Alternative Embodiments and Variations

Alternative embodiments could include the use of different AI algorithms, IoT protocols, or blockchain platforms. Variations could include the integration of additional technologies, such as machine learning-based recommendation engines or cloud-based data analytics platforms.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the fields of neurology, neuroscience, and medical technology, with potential applications in treating neurological disorders, such as epilepsy, Parkinson's disease, and chronic pain.

Field of Art

Neurological medical devices, specifically neural probe technologies with agent delivery systems, requiring advanced knowledge in biomedical engineering, neuroscience, materials science, and electronic systems integration

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or neurotechnology researcher with advanced degrees, expertise in neural interface design, familiarity with biomaterials, embedded systems, and interdisciplinary medical device development

Obviousness Rationale

A PHOSITA would recognize that integrating advanced digital technologies like AI, IoT, and blockchain with existing neural probe agent delivery systems represents a predictable technological evolution. The source patent's foundational neural probe design provides a clear technological framework that naturally invites computational and data management enhancements. The proposed variations represent logical extensions of existing neural interface technologies using well-established interdisciplinary engineering approaches.

Obvious Combinations & Variations

Source Patent Element
Dissolvable agent delivery structure for neural electrodes
PTD Variation
AI-powered agent delivery optimization based on patient-specific data
Obviousness Reasoning
Predictable application of machine learning to personalize existing agent delivery mechanisms, representing a known technique for improving medical device performance
Source Patent Element
Neural electrode with treatment agent delivery
PTD Variation
IoT-enabled sensors for real-time brain activity monitoring during agent delivery
Obviousness Reasoning
Integrating sensor technologies with existing medical devices is a standard engineering approach for enhancing diagnostic and therapeutic capabilities
Source Patent Element
Neural probe for delivering cannabinoid treatment agents
PTD Variation
Blockchain-based secure data storage for tracking stimulation and agent delivery protocols
Obviousness Reasoning
Applying distributed ledger technologies to medical device data management represents a logical extension of existing secure record-keeping practices
Source Patent Element
Electrode body with agent delivery capabilities
PTD Variation
Novel biomaterial coatings for enhanced agent release and neural interface performance
Obviousness Reasoning
Incremental materials science improvements to existing device substrates represent a predictable area of technological development
Source Patent Element
Neural stimulation device design
PTD Variation
Machine learning-based recommendation engine for selecting optimal therapy protocols
Obviousness Reasoning
Applying computational intelligence to medical treatment selection is a known technique for improving personalized healthcare interventions
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857326 and the disclosed technological variations, a Person Having Ordinary Skill In The Art would find the proposed neural probe system modifications obvious and lacking inventive step. The integration of AI, IoT, blockchain, and advanced biomaterials with existing neural electrode technologies represents a predictable combination of known techniques that would be apparent to a skilled practitioner in the field of neurological medical devices.

Original Patent Information

Patent NumberUS 11,857,326
TitleAgent-delivering neural probe devices and related systems and methods
Assignee(s)NeuroOne Medical Technologies Corporation