Advanced Microneedle Implantation System for Precise Micro-Device Delivery

Publication ID: 24-11857343_0005_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Advanced Microneedle Implantation System for Precise Micro-Device Delivery,” Published Technical Disclosure No. 24-11857343_0005_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857343_0005_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,343.

Summary of the Inventive Concept

The present inventive concept relates to a next-generation microneedle implantation system for precise delivery of micro-devices into biological tissues, featuring advanced sensors, real-time imaging, and robotic assistance for optimal placement and minimal tissue damage.

Background and Problem Solved

The original microneedle fabrication and device implantation patent addressed the need for precise microsurgical and neurosurgical techniques. However, the existing technology has limitations in terms of real-time monitoring, optimal placement, and minimizing tissue inflammation. The present inventive concept addresses these limitations by introducing advanced sensors, real-time imaging, and robotic assistance to revolutionize the field of microneedle implantation.

Detailed Description of the Inventive Concept

The advanced microneedle implantation system consists of a microneedle with a reversible engagement feature, a nanoscale sensor for real-time monitoring of tissue properties, and a micro-scale robotic arm for precise placement of the micro-device within the tissue. The system can also include a bio-compatible coating for minimizing tissue inflammation and a high-resolution imaging system for generating a three-dimensional map of the tissue. The microneedle is adapted to receive a micro-device and insert it into the tissue while the nanoscale sensor provides feedback for optimal placement. The system can further include a focused laser beam for ablating a section of the outer membrane of the tissue, allowing for precise insertion of the micro-device.

Novelty and Inventive Step

The present inventive concept introduces a paradigm shift in microneedle implantation technology by incorporating advanced sensors, real-time imaging, and robotic assistance, which are not present in the original patent. The combination of these features provides a next-generation solution for precise micro-device delivery, overcoming the limitations of the existing technology.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different types of sensors, such as optical or electrical sensors, or the integration of additional features, such as real-time feedback mechanisms or adaptive control systems. Variations of the system could also include different types of micro-devices, such as sensors, actuators, or drug delivery systems, or different implantation techniques, such as using multiple microneedles or combining microneedle implantation with other surgical techniques.

Potential Commercial Applications and Market

The advanced microneedle implantation system has significant commercial potential in the fields of neurosurgery, microsurgery, and biomedical research. The system could be used for a wide range of applications, including the delivery of micro-devices for neural prosthetics, brain-computer interfaces, or targeted drug delivery. The market for this technology is expected to grow rapidly, driven by the increasing demand for minimally invasive surgical techniques and the need for more precise and effective micro-device delivery systems.

CPC Classifications

SectionClassGroup
A A61 A61B5/685
A A61 A61B5/1459
A A61 A61B5/1473
A A61 A61B5/6868
A A61 A61K41/0028
A A61 A61N1/0502
A A61 A61N1/0529
A A61 A61N1/0551
A A61 A61N5/0601
B B21 B21F45/008
A A61 A61B2562/12
A A61 A61N2005/0612
A A61 A61N2005/0651
B B23 B23K1/0008
B B23 B23K2101/32

Original Patent Information

Patent NumberUS 11,857,343
TitleMicroneedle fabrication and device implantation
Assignee(s)The Regents of the University of California