Synergistic Microneedle Systems for Advanced Biological Tissue Interactions

Publication ID: 24-11857343_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Microneedle Systems for Advanced Biological Tissue Interactions,” Published Technical Disclosure No. 24-11857343_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857343_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,343.

Summary of the Inventive Concept

The integration of microneedle fabrication technology with AI, IoT, blockchain, and machine learning enables novel biological tissue interactions, such as precise implantation, real-time monitoring, and predictive analytics.

Background and Problem Solved

The original patent on microneedle fabrication and device implantation has limitations in terms of precision, safety, and data management. The new inventive concept addresses these limitations by combining the patented microneedle technology with advanced technologies to create a more powerful system.

Detailed Description of the Inventive Concept

The synergistic microneedle system comprises a microneedle fabricated according to the original patent, integrated with distinct technologies such as AI-powered navigation modules, IoT-enabled sensors, blockchain-based secure databases, and machine learning algorithms. The system enables precise implantation, real-time monitoring, and predictive analytics for biological tissue interactions. For instance, the AI-powered navigation module guides the microneedle through the tissue, while the IoT-enabled sensor detects the outer membrane's thickness. The blockchain-based secure database stores and transmits data from the microneedle, and the machine learning algorithm analyzes the data to predict the success of implantable device implantation.

Novelty and Inventive Step

The new claims introduce novel and non-obvious combinations of the patented microneedle technology with AI, IoT, blockchain, and machine learning. The integration of these technologies enables unprecedented precision, safety, and data management capabilities in biological tissue interactions.

Alternative Embodiments and Variations

Alternative embodiments of the synergistic microneedle system may include variations in the type of AI algorithm used, the specific IoT sensor technology employed, or the blockchain architecture utilized. Additionally, the system could be adapted for use in different biological tissues or applications, such as drug delivery or tissue engineering.

Potential Commercial Applications and Market

The synergistic microneedle system has significant commercial potential in the medical device industry, particularly in the areas of neurosurgery, orthopedics, and cardiology. The system's advanced capabilities in precision, safety, and data management make it an attractive solution for healthcare providers and researchers.

CPC Classifications

SectionClassGroup
A A61 A61B5/685
A A61 A61B5/1459
A A61 A61B5/1473
A A61 A61B5/6868
A A61 A61K41/0028
A A61 A61N1/0502
A A61 A61N1/0529
A A61 A61N1/0551
A A61 A61N5/0601
B B21 B21F45/008
A A61 A61B2562/12
A A61 A61N2005/0612
A A61 A61N2005/0651
B B23 B23K1/0008
B B23 B23K2101/32

Original Patent Information

Patent NumberUS 11,857,343
TitleMicroneedle fabrication and device implantation
Assignee(s)The Regents of the University of California