Microneedle Array-Based Sensors for Diverse Applications

Publication ID: 24-11857344_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Microneedle Array-Based Sensors for Diverse Applications,” Published Technical Disclosure No. 24-11857344_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857344_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,344.

Summary of the Inventive Concept

The invention leverages the core technology of microneedle array-based analyte monitoring to create novel sensors for various industries, including aquaculture, precision agriculture, athletic performance monitoring, pharmaceutical authentication, and environmental pollution detection.

Background and Problem Solved

The original patent focused on continuous glucose monitoring for diabetes patients. However, the limitations of this technology lie in its narrow application scope. The new inventive concept addresses this limitation by exploring the potential of microneedle array-based sensors in diverse fields, where real-time monitoring and accurate detection are crucial.

Detailed Description of the Inventive Concept

The new inventive concept comprises microneedle array-based sensors adapted for specific applications. For instance, in aquaculture, the sensor detects changes in water chemistry indicative of disease or stress in aquatic organisms. In precision agriculture, the sensor monitors nutrient levels and pH in soil, enabling optimized fertilizer application and irrigation schedules. Similarly, in athletic performance monitoring, the sensor detects changes in lactate levels, pH, and other biomarkers in sweat, providing real-time feedback to athletes. In pharmaceutical authentication, the sensor detects differences in chemical composition between authentic and counterfeit drugs. Lastly, in environmental pollution detection, the sensor detects changes in pollutant levels in air or water, triggering alerts and notifications to regulatory agencies.

Novelty and Inventive Step

The new inventive concept is novel and non-obvious in its application of microneedle array-based sensors to diverse industries, which was not contemplated in the original patent. The inventive step lies in the adaptation of the core technology to address specific problems and challenges in these new fields.

Alternative Embodiments and Variations

Alternative embodiments may include varying sensor configurations, materials, and geometries to optimize performance in specific applications. Variations may also involve integrating multiple sensors to detect a broader range of analytes or combining sensors with other technologies, such as machine learning algorithms, to enhance data analysis and decision-making.

Potential Commercial Applications and Market

The new inventive concept has significant commercial potential in various industries, including aquaculture, agriculture, sports technology, pharmaceuticals, and environmental monitoring. The target market includes companies, research institutions, and government agencies seeking innovative solutions for real-time monitoring and accurate detection in their respective fields.

CPC Classifications

SectionClassGroup
A A61 A61B5/685
A A61 A61B5/14514
A A61 A61B5/14532

Field of Art

Biomedical sensing technologies, specifically electrochemical sensors for continuous analyte monitoring, with expertise in microneedle array design, sensor signal processing, and multi-domain sensor applications

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or sensor design specialist with advanced degree, proficient in electrochemical sensing techniques, microelectrode fabrication, signal processing algorithms, and interdisciplinary sensor adaptation strategies

Obviousness Rationale

A PHOSITA would recognize the fundamental microneedle array sensing technology disclosed in the source patent as a versatile platform capable of adaptation across multiple domains. The core electrochemical sensing principles demonstrated in the glucose monitoring context can be readily translated to alternative analyte detection scenarios by modifying electrode coatings, signal processing algorithms, and sensor geometry. The technical foundations established in the source patent provide a clear roadmap for extending the sensing methodology to diverse monitoring applications.

Obvious Combinations & Variations

Source Patent Element
Electrochemical working electrode with sensing coating for generating current indicative of redox reactions
PTD Variation
Adapting electrode coating and sensor configuration for detecting water chemistry, soil nutrients, sweat biomarkers, and pharmaceutical composition
Obviousness Reasoning
Known technique of modifying electrode surface chemistry to enable selective analyte detection, with predictable results in different sensing domains
Source Patent Element
Controller configured to process voltage and current signals for fault detection
PTD Variation
Implementing signal processing algorithms to generate alerts for aquaculture, athletic performance, and environmental monitoring applications
Obviousness Reasoning
Applying established signal processing techniques to new monitoring contexts represents a standard design choice for a PHOSITA
Source Patent Element
Microneedle array positioned to interface with biological or chemical environment
PTD Variation
Extending microneedle array deployment to soil, sweat, pharmaceutical samples, and environmental media
Obviousness Reasoning
Predictable extension of existing sensor interface technology to alternative sampling environments using known microengineering techniques
Source Patent Element
Voltage and current correlation methods for sensing validation
PTD Variation
Implementing similar signal validation techniques across diverse sensing applications to ensure measurement reliability
Obviousness Reasoning
Transferring robust signal processing methodologies represents a standard engineering approach to sensor design across domains
Source Patent Element
Continuous analyte monitoring device with real-time data processing
PTD Variation
Creating multi-domain sensor systems with integrated controllers for generating actionable insights
Obviousness Reasoning
Logical progression of sensor technology from single-domain to multi-domain applications using known system integration techniques
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857344, a Person Having Ordinary Skill In The Art would find the disclosed microneedle array sensor variations in the accompanying Published Technical Disclosure to be obvious extensions of the foundational electrochemical sensing methodology. The technical variations represent predictable adaptations of core sensing principles to alternative analyte monitoring domains, employing standard engineering design choices that would be apparent to a skilled practitioner in the field.

Original Patent Information

Patent NumberUS 11,857,344
TitleFault detection for microneedle array based continuous analyte monitoring device
Assignee(s)Biolinq Incorporated