Positron Imaging Tomography for Niche Environments

Publication ID: 24-11857352_0004_PTD
Published: October 28, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Positron Imaging Tomography for Niche Environments,” Published Technical Disclosure No. 24-11857352_0004_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857352_0004_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,352.

Summary of the Inventive Concept

This inventive concept adapts positron imaging tomography for bacterial infection detection in specialized scenarios, including extreme weather conditions, high-security facilities, disaster relief, and remote or resource-limited areas.

Background and Problem Solved

The original patent for positron imaging tomography imaging agent composition and method for bacterial infection detection has limitations in its applicability to specific, narrow markets or unique operational environments. This inventive concept addresses these limitations by developing specialized variations and niche solutions.

Detailed Description of the Inventive Concept

The new inventive concept comprises a system, method, and composition for detecting bacterial infections in extreme weather conditions, high-security facilities, disaster relief scenarios, and remote or resource-limited areas. The composition includes a specific ratio of 4-amino-2-[18F]-fluorobenzoic acid to 4-amino-2-[19F]-fluorobenzoic acid, adapted for use in these niche environments. The system and method utilize portable imaging devices, secure imaging devices, and compact imaging devices to detect bacterial infections in these specialized scenarios.

Novelty and Inventive Step

The new claims introduce novel and non-obvious adaptations of the original patent's composition and method to address the specific challenges of extreme weather conditions, high-security facilities, disaster relief, and remote or resource-limited areas. The inventive step lies in the selection of specific ratios of 4-amino-2-[18F]-fluorobenzoic acid to 4-amino-2-[19F]-fluorobenzoic acid and the development of specialized imaging devices for these niche environments.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include adaptations for other specialized scenarios, such as space exploration, underwater operations, or high-altitude environments. Variations of the composition and method could also be developed for specific types of bacterial infections or in conjunction with other diagnostic tools.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the fields of healthcare, biotechnology, and medical imaging, particularly in the development of specialized diagnostic tools for niche environments. The target industries include disaster relief organizations, high-security facilities, and remote or resource-limited area healthcare providers.

CPC Classifications

SectionClassGroup
A A61 A61B6/037
A A61 A61K51/0402
A A61 A61P31/04
C C07 C07B59/001
C C07 C07C227/12
C C07 C07C229/60

Field of Art

Medical imaging, radiopharmaceutical composition, and bacterial infection diagnostics, involving advanced molecular imaging techniques and radioisotope chemistry

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degrees in radiochemistry, nuclear medicine, or biomedical engineering, possessing expertise in positron emission tomography (PET) imaging agents, radioisotope synthesis, and diagnostic methodologies

Obviousness Rationale

A PHOSITA would recognize that adapting the source patent's positron imaging composition to specialized environmental contexts represents a predictable variation within the established technological framework. The core molecular structure and radiochemical principles remain consistent, with modifications focused on deployment scenarios and imaging device configurations. Such adaptations would be considered routine optimization within the field of medical diagnostic imaging technologies.

Obvious Combinations & Variations

Source Patent Element
Composition with specific ratios of 4-amino-2-[18F]-fluorobenzoic acid to 4-amino-2-[19F]-fluorobenzoic acid
PTD Variation
Applying the composition to extreme weather, high-security, disaster relief, and remote environment scenarios
Obviousness Reasoning
Adapting diagnostic imaging technologies to different operational contexts represents a standard design choice for medical imaging professionals, involving predictable engineering modifications
Source Patent Element
Radiochemical composition for bacterial infection detection
PTD Variation
Developing portable and compact imaging devices tailored to specific environmental constraints
Obviousness Reasoning
Miniaturization and environmental adaptation of medical imaging equipment is a known technique in the field, representing incremental technological development
Source Patent Element
Base radioisotope imaging methodology
PTD Variation
Introducing alternative embodiments for space exploration, underwater operations, and high-altitude environments
Obviousness Reasoning
Extending diagnostic technologies to novel operational domains is a predictable progression for skilled practitioners seeking to expand technological applicability
Source Patent Element
Radiochemical composition with specific isotope ratios
PTD Variation
Modifying isotope ratios slightly to accommodate different environmental or diagnostic requirements
Obviousness Reasoning
Fine-tuning radiochemical compositions within established ranges represents routine optimization for a person skilled in radiopharmaceutical development
Source Patent Element
Bacterial infection detection methodology
PTD Variation
Integrating supplementary diagnostic tools and temperature management devices
Obviousness Reasoning
Combining known medical diagnostic technologies to enhance detection and treatment effectiveness is a standard approach in medical technology development
35 U.S.C. § 103 Summary: Pursuant to 35 U.S.C. ยง 103, the variations disclosed in this Published Technical Disclosure (PTD) would have been obvious to a Person Having Ordinary Skill In The Art at the time of invention, when considered in light of US Patent 11857352. The PTD demonstrates that the claimed innovations represent predictable extensions of the source patent's foundational radiochemical composition and bacterial infection detection methodology, employing routine technological adaptations within the established scientific framework.

Original Patent Information

Patent NumberUS 11,857,352
TitlePositron imaging tomography imaging agent composition and method for bacterial infection
Assignee(s)The Research Foundation for The State of University New York