Enhanced Positron Imaging Tomography for Bacterial Infection Diagnosis

Publication ID: 24-11857352_0006_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Positron Imaging Tomography for Bacterial Infection Diagnosis,” Published Technical Disclosure No. 24-11857352_0006_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857352_0006_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,352.

Summary of the Inventive Concept

A novel system and method for positron imaging tomography that improves the diagnosis of bacterial infections by enhancing radiochemical purity, dynamic ratio adjustment, and image resolution.

Background and Problem Solved

The original patent for positron imaging tomography imaging agent composition and method for bacterial infection has limitations in terms of radiochemical purity, ratio control, and image resolution. The new inventive concept addresses these limitations by introducing a novel injector module, dynamic ratio adjustment, and enhanced detector module, thereby providing a more efficient and accurate diagnosis of bacterial infections.

Detailed Description of the Inventive Concept

The new inventive concept comprises a novel injector module that incorporates a multi-step purification process to remove impurities and increase the yield of the radiolabeled compound. Additionally, the system includes a method for dynamically adjusting the ratio of 4-amino-2-[18F]-fluorobenzoic acid to 4-amino-2-[19F]-fluorobenzoic acid in real-time during the imaging process. Furthermore, the positron imaging tomography apparatus features an enhanced detector module with a proprietary algorithm for improved image resolution and reduced artifacts. The composition also includes a novel stabilizer that maintains the radiochemical purity of the radiolabeled compounds.

Novelty and Inventive Step

The new inventive concept is novel and non-obvious compared to the original patent due to the introduction of the novel injector module, dynamic ratio adjustment, and enhanced detector module. These features provide a significant improvement in radiochemical purity, ratio control, and image resolution, thereby enhancing the accuracy and efficiency of bacterial infection diagnosis.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include variations in the injector module design, such as using different purification methods or materials. Additionally, the dynamic ratio adjustment could be implemented using different algorithms or control systems. The enhanced detector module could also be modified to accommodate different imaging modalities or applications.

Potential Commercial Applications and Market

The new inventive concept has significant commercial potential in the medical imaging industry, particularly in the diagnosis and treatment of bacterial infections. The target market includes hospitals, research institutions, and pharmaceutical companies involved in the development of positron imaging tomography agents and imaging systems.

CPC Classifications

SectionClassGroup
A A61 A61B6/037
A A61 A61K51/0402
A A61 A61P31/04
C C07 C07B59/001
C C07 C07C227/12
C C07 C07C229/60

Original Patent Information

Patent NumberUS 11,857,352
TitlePositron imaging tomography imaging agent composition and method for bacterial infection
Assignee(s)The Research Foundation for The State of University New York