Enhanced Positron Imaging Tomography for Bacterial Infection Diagnosis
Legal Citation
Summary of the Inventive Concept
A novel system and method for positron imaging tomography that improves the diagnosis of bacterial infections by enhancing radiochemical purity, dynamic ratio adjustment, and image resolution.
Background and Problem Solved
The original patent for positron imaging tomography imaging agent composition and method for bacterial infection has limitations in terms of radiochemical purity, ratio control, and image resolution. The new inventive concept addresses these limitations by introducing a novel injector module, dynamic ratio adjustment, and enhanced detector module, thereby providing a more efficient and accurate diagnosis of bacterial infections.
Detailed Description of the Inventive Concept
The new inventive concept comprises a novel injector module that incorporates a multi-step purification process to remove impurities and increase the yield of the radiolabeled compound. Additionally, the system includes a method for dynamically adjusting the ratio of 4-amino-2-[18F]-fluorobenzoic acid to 4-amino-2-[19F]-fluorobenzoic acid in real-time during the imaging process. Furthermore, the positron imaging tomography apparatus features an enhanced detector module with a proprietary algorithm for improved image resolution and reduced artifacts. The composition also includes a novel stabilizer that maintains the radiochemical purity of the radiolabeled compounds.
Novelty and Inventive Step
The new inventive concept is novel and non-obvious compared to the original patent due to the introduction of the novel injector module, dynamic ratio adjustment, and enhanced detector module. These features provide a significant improvement in radiochemical purity, ratio control, and image resolution, thereby enhancing the accuracy and efficiency of bacterial infection diagnosis.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include variations in the injector module design, such as using different purification methods or materials. Additionally, the dynamic ratio adjustment could be implemented using different algorithms or control systems. The enhanced detector module could also be modified to accommodate different imaging modalities or applications.
Potential Commercial Applications and Market
The new inventive concept has significant commercial potential in the medical imaging industry, particularly in the diagnosis and treatment of bacterial infections. The target market includes hospitals, research institutions, and pharmaceutical companies involved in the development of positron imaging tomography agents and imaging systems.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61B6/037 |
| A | A61 | A61K51/0402 |
| A | A61 | A61P31/04 |
| C | C07 | C07B59/001 |
| C | C07 | C07C227/12 |
| C | C07 | C07C229/60 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Medical imaging and radiopharmaceutical composition, specifically positron emission tomography (PET) for bacterial infection detection, involving radiochemical synthesis, imaging techniques, and molecular diagnostics
Person of Ordinary Skill (PHOSITA) Profile
A professional with advanced degrees in radiochemistry, nuclear medicine, or biomedical engineering, possessing expertise in radiolabeled compound preparation, imaging system design, and diagnostic imaging optimization
Obviousness Rationale
A person having ordinary skill in the art would recognize that the published technical disclosure represents predictable variations and incremental improvements to the source patent's core technology. The proposed enhancements in injector module design, ratio adjustment, and detector sensitivity represent standard engineering approaches to refining diagnostic imaging systems. These modifications would be considered routine optimization techniques within the established technological framework of positron imaging tomography.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,352 |
|---|---|
| Title | Positron imaging tomography imaging agent composition and method for bacterial infection |
| Assignee(s) | The Research Foundation for The State of University New York |