Positron Imaging Tomography for Novel Applications

Publication ID: 24-11857352_0007_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Positron Imaging Tomography for Novel Applications,” Published Technical Disclosure No. 24-11857352_0007_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857352_0007_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,352.

Summary of the Inventive Concept

This inventive concept expands the original positron imaging tomography technology to novel applications, including detecting fungal infections in agricultural crops, monitoring antimicrobial coatings on medical implants, detecting biofilm formation on medical devices, tracking stem cell migration, and diagnosing chronic wounds.

Background and Problem Solved

The original patent's positron imaging tomography technology has been limited to diagnosing bacterial infections. However, the growing need for innovative solutions in various industries has created an opportunity to apply this technology to new fields. This inventive concept addresses the lack of effective diagnostic tools in these areas, providing a novel approach to tackle complex problems.

Detailed Description of the Inventive Concept

The new inventive concept leverages the core technology of the original patent to develop novel applications. The positron imaging tomography imaging agent composition and method are adapted to detect fungal infections in agricultural crops, monitor antimicrobial coatings on medical implants, detect biofilm formation on medical devices, track stem cell migration, and diagnose chronic wounds. These new applications utilize the same principles of positron imaging tomography but are tailored to the specific requirements of each field.

Novelty and Inventive Step

The new claims introduce novel applications of the original positron imaging tomography technology, which are non-obvious and unanticipated by the original patent. The inventive step lies in the adaptation of the technology to address distinct problems in different industries, demonstrating a significant expansion of the original concept.

Alternative Embodiments and Variations

Alternative embodiments of this inventive concept could include the development of new positron imaging tomography imaging agent compositions tailored to specific applications, the integration of the technology with other diagnostic tools, or the use of different isotopes for imaging. Variations could also include the application of this technology to other industries, such as veterinary medicine or environmental monitoring.

Potential Commercial Applications and Market

The potential commercial applications of this inventive concept are vast, with opportunities in agriculture, medical devices, and healthcare. The market demand for innovative diagnostic tools in these industries is significant, and this technology has the potential to disrupt traditional methods and improve outcomes.

CPC Classifications

SectionClassGroup
A A61 A61B6/037
A A61 A61K51/0402
A A61 A61P31/04
C C07 C07B59/001
C C07 C07C227/12
C C07 C07C229/60

Field of Art

Molecular Imaging and Radiopharmaceutical Diagnostics, involving positron emission tomography (PET) imaging technologies with specific focus on fluorinated imaging agents for detecting biological processes

Person of Ordinary Skill (PHOSITA) Profile

A skilled practitioner with advanced training in radiochemistry, nuclear medicine, molecular imaging, and diagnostic technologies, capable of understanding complex isotope-based imaging techniques and adapting imaging methodologies across different biological contexts

Obviousness Rationale

A person having ordinary skill in the art would recognize that the core positron imaging tomography technology disclosed in the source patent represents a versatile diagnostic platform that can be systematically adapted to multiple biological detection scenarios. The fundamental principles of fluorinated imaging agents and positron emission detection are transferable across different biological contexts, making the novel applications in the PTD predictable extensions of the original technological framework. The variations represent logical technological expansions that leverage the established diagnostic methodology to address related detection challenges in different domains.

Obvious Combinations & Variations

Source Patent Element
Positron imaging tomography imaging agent composition using fluorinated benzoic acid derivatives
PTD Variation
Application of imaging agent for detecting fungal infections in agricultural crops
Obviousness Reasoning
Known technique of adapting diagnostic imaging technologies across biological systems, with predictable results in detecting metabolic/structural changes in organisms
Source Patent Element
Fluorinated imaging agent with specific isotope ratios for bacterial detection
PTD Variation
Monitoring antimicrobial coatings on medical implants using similar imaging principles
Obviousness Reasoning
Predictable extension of existing diagnostic methodology to evaluate surface interactions and microbial presence using established imaging techniques
Source Patent Element
Positron emission detection methodology for identifying biological processes
PTD Variation
Tracking stem cell migration using imaging agent composition
Obviousness Reasoning
Known approach of utilizing molecular imaging techniques to trace cellular movements, representing a straightforward technological adaptation
Source Patent Element
Fluorinated benzoic acid-based imaging composition for detecting biological processes
PTD Variation
Diagnosing and monitoring chronic wounds using positron imaging
Obviousness Reasoning
Logical application of existing diagnostic technology to evaluate tissue metabolic changes and inflammatory processes
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857352 and the published technical disclosure, a person having ordinary skill in the art would find the disclosed variations of positron imaging tomography applications to be obvious extensions of the existing technological framework, rendering potential claims to such variations unpatentable under 35 U.S.C. ยง 103 due to the predictable and systematic adaptability of the core diagnostic methodology across diverse biological detection contexts.

Original Patent Information

Patent NumberUS 11,857,352
TitlePositron imaging tomography imaging agent composition and method for bacterial infection
Assignee(s)The Research Foundation for The State of University New York