Synergistic Integration of Positron Emission Tomography (PET) Imaging with AI, IoT, Blockchain, and Advanced Materials for Enhanced Bacterial Infection Diagnosis and Treatment

Publication ID: 24-11857352_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Integration of Positron Emission Tomography (PET) Imaging with AI, IoT, Blockchain, and Advanced Materials for Enhanced Bacterial Infection Diagnosis and Treatment,” Published Technical Disclosure No. 24-11857352_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857352_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,352.

Summary of the Inventive Concept

The inventive concept combines the original PET imaging agent composition with distinct technologies to create a more powerful system for diagnosing and treating bacterial infections, offering improved accuracy, efficiency, and personalized medicine.

Background and Problem Solved

The original patent disclosed a PET imaging agent composition for bacterial infection diagnosis, but it had limitations in image analysis, data security, and treatment monitoring. The new inventive concept addresses these limitations by integrating AI, IoT, blockchain, and advanced materials to provide a more comprehensive and effective solution.

Detailed Description of the Inventive Concept

The inventive concept comprises a PET imaging agent composition of 4-amino-2-[18F]-fluorobenzoic acid and 4-amino-2-[19F]-fluorobenzoic acid, combined with AI algorithms for image analysis and disease detection, IoT sensors for real-time treatment monitoring, blockchain technology for secure data storage and sharing, and novel materials for enhanced imaging sensitivity and specificity. This synergistic integration enables accurate diagnosis, personalized treatment, and efficient disease management.

Novelty and Inventive Step

The new claims introduce non-obvious combinations of the original PET imaging agent composition with AI, IoT, blockchain, and advanced materials, providing a novel and inventive solution for bacterial infection diagnosis and treatment.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different AI algorithms, IoT sensor configurations, blockchain architectures, or advanced materials. Variations could also include the integration of additional technologies, such as machine learning or robotics, to further enhance the system's capabilities.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the healthcare industry, particularly in the areas of infectious disease diagnosis and treatment. Target markets include hospitals, research institutions, and pharmaceutical companies, with potential applications in personalized medicine, disease surveillance, and public health management.

CPC Classifications

SectionClassGroup
A A61 A61B6/037
A A61 A61K51/0402
A A61 A61P31/04
C C07 C07B59/001
C C07 C07C227/12
C C07 C07C229/60

Field of Art

Medical imaging, radiopharmaceuticals, and diagnostic technologies, specifically focused on positron emission tomography (PET) for bacterial infection detection with expertise in molecular imaging, radiochemistry, and advanced diagnostic technologies

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degrees in medical imaging, radiochemistry, or biomedical engineering, possessing knowledge of PET imaging techniques, AI integration, sensor technologies, and advanced medical data management systems

Obviousness Rationale

A PHOSITA would recognize that integrating the source patent's PET imaging agent composition with emerging technologies like AI, IoT, and blockchain represents a predictable combination of known techniques in medical diagnostics. The technical elements are well-established in their respective domains, and the integration follows standard interdisciplinary approaches for enhancing medical imaging and diagnostic capabilities. The variations demonstrate systematic technological augmentation rather than non-obvious innovation.

Obvious Combinations & Variations

Source Patent Element
PET imaging agent composition with specific fluorobenzoic acid ratios
PTD Variation
Integration of AI algorithms for automated image analysis and disease detection
Obviousness Reasoning
AI-assisted medical image interpretation is a known technique, and applying machine learning to PET imaging represents a predictable technological progression with expected improvements in diagnostic accuracy
Source Patent Element
Bacterial infection diagnostic composition
PTD Variation
IoT sensor integration for real-time treatment monitoring
Obviousness Reasoning
Continuous medical monitoring through networked sensors is a standard approach in modern healthcare, representing an obvious extension of existing diagnostic technologies
Source Patent Element
Radiochemical imaging composition
PTD Variation
Blockchain-based secure medical data management system
Obviousness Reasoning
Blockchain technology for secure medical data storage is a well-known solution in healthcare informatics, representing a straightforward technological adaptation with predictable results
Source Patent Element
Fluorobenzoic acid-based imaging agent
PTD Variation
Metal-organic framework (MOF) composite for enhanced imaging sensitivity
Obviousness Reasoning
Material science enhancements to imaging technologies are routine in diagnostic development, with finite known approaches for improving signal detection and specificity
35 U.S.C. § 103 Summary: Pursuant to 35 U.S.C. ยง 103, the variations disclosed herein would be obvious to a person having ordinary skill in the art at the time of invention, as they represent predictable combinations of known technologies extending the foundational teachings of US Patent 11857352, with each technological integration demonstrating systematic, incremental advancement within the established boundaries of medical imaging and diagnostic technologies.

Original Patent Information

Patent NumberUS 11,857,352
TitlePositron imaging tomography imaging agent composition and method for bacterial infection
Assignee(s)The Research Foundation for The State of University New York