Next-Generation Angiographic Examination System

Publication ID: 24-11857354_0010_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Next-Generation Angiographic Examination System,” Published Technical Disclosure No. 24-11857354_0010_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857354_0010_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,354.

Summary of the Inventive Concept

The next-generation angiographic examination system leverages machine learning, artificial intelligence, and advanced imaging modalities to revolutionize vascular interventions, enabling precise, efficient, and personalized treatments.

Background and Problem Solved

The original angiographic examination method (Patent US 7,500,784 B2) relies on traditional X-ray imaging, which has limitations in terms of resolution, accuracy, and patient safety. The new inventive concept addresses these limitations by integrating advanced technologies to provide real-time, high-resolution imaging and personalized treatment planning.

Detailed Description of the Inventive Concept

The next-generation angiographic examination system consists of a machine learning-based image analysis module, a high-resolution optical coherence tomography (OCT) system, and a robotic-assisted catheter navigation module. The system utilizes real-time feedback from fluoroscopy and OCT imaging to enable precise and minimally invasive vascular interventions. Additionally, the system generates personalized, 3D-printed vascular models for pre-operative planning and simulation, using data from a patient's pre-interventional CT or MRI scans.

Novelty and Inventive Step

The new inventive concept introduces a paradigm shift in angiographic examination by integrating machine learning, artificial intelligence, and advanced imaging modalities, which enables real-time, high-resolution imaging and personalized treatment planning. This represents a significant departure from traditional X-ray imaging and constitutes a non-obvious improvement over the original patent.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of other advanced imaging modalities, such as ultrasound or MRI, or the integration of additional machine learning algorithms for improved image analysis and treatment planning. Variations of the system could also be designed for specific vascular interventions, such as stent graft placement or angioplasty.

Potential Commercial Applications and Market

The next-generation angiographic examination system has significant commercial potential in the medical device industry, particularly in the fields of vascular interventions and personalized medicine. The system could be marketed to hospitals, clinics, and medical research institutions, with potential applications in cardiovascular disease treatment, cancer therapy, and neurointerventions.

CPC Classifications

SectionClassGroup
A A61 A61B6/12
A A61 A61B6/03
A A61 A61B6/4441
A A61 A61B6/463
A A61 A61B6/504
A A61 A61B6/5235
G G06 G06T7/30
A A61 A61B6/4458
A A61 A61B6/481
A A61 A61B6/487
A A61 A61B6/5223
G G06 G06T2207/10081
G G06 G06T2207/30101

Field of Art

Medical imaging and interventional radiology, specifically angiographic examination systems involving X-ray, CT, fluoroscopy, and advanced imaging technologies for vascular interventions

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical imaging specialist with expertise in interventional radiology, advanced imaging modalities, machine learning applications in medical diagnostics, and robotic-assisted medical technologies

Obviousness Rationale

A person having ordinary skill in the art would recognize that the published technical disclosure represents predictable combinations of known medical imaging technologies and techniques. The integration of machine learning, AI-driven image processing, and advanced imaging modalities like OCT are logical extensions of existing angiographic examination methods. These variations represent incremental improvements using standard engineering approaches to enhance medical imaging precision and diagnostic capabilities.

Obvious Combinations & Variations

Source Patent Element
3D volume data capture from CT angiography or C-arm CT
PTD Variation
Machine learning-based image analysis module for predicting optimal stent graft placement using patient-specific anatomical data
Obviousness Reasoning
Extending 3D imaging techniques with machine learning is a predictable application of existing image processing technologies to improve diagnostic accuracy and treatment planning
Source Patent Element
X-ray emitter and image detector on C-arm configuration
PTD Variation
Replacing X-ray with high-resolution optical coherence tomography (OCT) imaging system
Obviousness Reasoning
Substituting imaging modalities is a known technique in medical imaging, with OCT offering complementary visualization capabilities to traditional X-ray methods
Source Patent Element
Vessel center line and lumina tracking in angiographic examination
PTD Variation
Robotic-assisted catheter navigation using real-time fluoroscopy and OCT feedback
Obviousness Reasoning
Integrating robotic guidance with existing vessel tracking techniques represents a logical progression in minimally invasive medical intervention technologies
Source Patent Element
2D polygon line generation for medical instrument positioning
PTD Variation
AI-driven image processing for real-time tracking of stent graft deployment
Obviousness Reasoning
Enhancing instrument tracking with artificial intelligence is a predictable evolution of existing medical imaging instrument localization techniques
Source Patent Element
Angiographic examination method using 3D volume data
PTD Variation
Generating personalized 3D-printed vascular models from pre-interventional CT or MRI scans
Obviousness Reasoning
Utilizing existing 3D imaging data for physical model creation is an obvious application of advanced medical imaging and additive manufacturing technologies
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857354 and the published technical disclosure, a person having ordinary skill in the art would find the claimed variations obvious through predictable combinations of known medical imaging technologies. The disclosed system represents incremental improvements using standard engineering approaches to enhance angiographic examination methods, thereby rendering potential patent claims obvious and anticipatable as prior art.

Original Patent Information

Patent NumberUS 11,857,354
TitleAngiographic examination method for a vascular system
Assignee(s)Siemens Healthcare Limited