Next-Generation Synthetic Breast Tissue Image Generation with AI-Driven High-Density Element Suppression

Publication ID: 24-11857358_0005_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Next-Generation Synthetic Breast Tissue Image Generation with AI-Driven High-Density Element Suppression,” Published Technical Disclosure No. 24-11857358_0005_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857358_0005_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,358.

Summary of the Inventive Concept

A novel system and method for generating synthetic breast tissue images with enhanced high-density element suppression using artificial intelligence and machine learning techniques, enabling improved breast cancer diagnosis and risk assessment.

Background and Problem Solved

The original patent disclosed a system and method for processing images of breast tissue that included obtrusive high-density elements. However, this approach had limitations in terms of image quality and the ability to accurately suppress high-density elements. The new inventive concept addresses these limitations by leveraging AI-driven techniques to improve image quality and enhance high-density element suppression, enabling more accurate breast cancer diagnosis and risk assessment.

Detailed Description of the Inventive Concept

The new inventive concept comprises a neural network trained on a dataset of breast images to predict and suppress high-density elements, integrated with an image processor configured to generate a 3D image volume from a plurality of 2D projection images. The neural network is trained to adapt to new image data, enabling real-time image processing and high-density element suppression. The system can also include a database of breast images annotated with high-density element information, which is used to train the machine learning model. The machine learning model is integrated with the image processor to enable real-time image analysis and high-density element suppression.

Novelty and Inventive Step

The new inventive concept introduces the use of AI-driven techniques, specifically neural networks and machine learning algorithms, to improve image quality and enhance high-density element suppression. This approach is novel and non-obvious compared to the original patent, which relied on traditional image processing methods.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different AI-driven techniques, such as deep learning algorithms or computer vision methods, to improve image quality and enhance high-density element suppression. Additionally, the system could be adapted for use in other medical imaging applications, such as lung or liver imaging.

Potential Commercial Applications and Market

The new inventive concept has significant commercial potential in the medical imaging industry, particularly in the area of breast cancer diagnosis and risk assessment. The system could be marketed to hospitals, clinics, and imaging centers, and could also be used in research settings to improve our understanding of breast cancer and develop new treatments.

CPC Classifications

SectionClassGroup
A A61 A61B6/5258
A A61 A61B6/461
A A61 A61B6/502
G G06 G06T11/008
G G06 G06T2207/10116
G G06 G06T2207/30068

Field of Art

Medical imaging, specifically breast tissue tomosynthesis and synthetic image generation, involving digital image processing, machine learning, and radiological diagnostic technologies

Person of Ordinary Skill (PHOSITA) Profile

A skilled practitioner with expertise in medical imaging, computer vision, machine learning, and radiological image processing, holding advanced degrees in biomedical engineering, computer science, or medical imaging, with working knowledge of neural networks and image reconstruction techniques

Obviousness Rationale

A person having ordinary skill would recognize that applying machine learning techniques to the existing synthetic breast tissue image generation process represents a predictable technological evolution. The source patent's fundamental image processing framework provides a clear foundation for integrating AI-driven techniques to enhance high-density element suppression. The PTD's neural network approach is a logical extension of existing image processing methodologies, utilizing well-established machine learning principles to improve diagnostic imaging capabilities.

Obvious Combinations & Variations

Source Patent Element
Image processor generating 3D image volume from multiple 2D projection images
PTD Variation
Integrating neural network for adaptive high-density element suppression within the image processing workflow
Obviousness Reasoning
Applying machine learning to existing image reconstruction techniques represents a known approach for improving image quality, with predictable results in medical imaging processing
Source Patent Element
X-ray image acquisition of breast tissue at multiple angles
PTD Variation
Using AI-trained models to enhance image processing and high-density element identification
Obviousness Reasoning
Enhancing traditional imaging techniques with machine learning is a standard method of improving diagnostic capabilities, representing an obvious technological progression
Source Patent Element
2D projection image processing for synthetic image generation
PTD Variation
Implementing deep learning algorithms to adaptively process and reconstruct medical images
Obviousness Reasoning
Substituting traditional image processing algorithms with neural network techniques is a well-understood optimization strategy in medical imaging technologies
Source Patent Element
Breast tissue image generation system
PTD Variation
Adding real-time risk assessment capabilities through integrated machine learning models
Obviousness Reasoning
Extending diagnostic imaging systems with predictive analytics is a foreseeable development in medical imaging technology
Source Patent Element
High-density element suppression methodology
PTD Variation
Implementing AI-driven techniques for more sophisticated element identification and suppression
Obviousness Reasoning
Applying advanced computational techniques to improve existing image processing methods represents a natural technological progression with predictable outcomes
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857358 and the disclosed variations, a person having ordinary skill in medical imaging would find the proposed AI-enhanced synthetic breast tissue image generation techniques obvious and non-inventive. The combination of known image processing methodologies with machine learning approaches represents a predictable technological evolution that would be readily conceived by a skilled practitioner in the field of medical imaging and diagnostic technologies.

Original Patent Information

Patent NumberUS 11,857,358
TitleSystem and method for synthetic breast tissue image generation by high density element suppression
Assignee(s)Hologic, Inc.