Advanced Ultrasound-Guided Tissue Sampling System

Publication ID: 24-11857365_0003_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Advanced Ultrasound-Guided Tissue Sampling System,” Published Technical Disclosure No. 24-11857365_0003_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857365_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,365.

Summary of the Inventive Concept

The inventive concept integrates a dual-lumen catheter with distinct technologies, such as AI, IoT, blockchain, nanomaterials, MEMS sensors, and 3D printing, to create a more powerful system for ultrasound-guided tissue sampling, enabling real-time analysis, remote monitoring, and customized sampling devices.

Background and Problem Solved

The original patent, 'Dual Lumen Catheter,' addressed the limitations of current tools for ultrasound visualization and sampling of peripheral lung tumors. However, it did not leverage advancements in AI, IoT, blockchain, and other technologies to enhance the diagnostic and therapeutic capabilities of the catheter. The new inventive concept solves this problem by integrating these technologies to create a more comprehensive and effective system.

Detailed Description of the Inventive Concept

The inventive concept comprises a dual-lumen catheter, an artificial intelligence module, an IoT network, a blockchain-based data storage system, a nanomaterial-based coating, a MEMS sensor, and a 3D printing module. The AI module analyzes ultrasound images obtained through the catheter and stores the analysis results in the blockchain-based data storage system, ensuring secure and transparent data management. The IoT network enables remote monitoring and control of the catheter during the sampling procedure, while the nanomaterial-based coating enhances the catheter's biocompatibility. The MEMS sensor provides real-time feedback during the sampling procedure, and the 3D printing module creates customized sampling devices based on the identified optimal sampling locations.

Novelty and Inventive Step

The new claims introduce a synergistic combination of distinct technologies, which is not obvious from the original patent. The integration of AI, IoT, blockchain, nanomaterials, MEMS sensors, and 3D printing with the dual-lumen catheter provides a novel and non-obvious solution for ultrasound-guided tissue sampling.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include integrating the dual-lumen catheter with other technologies, such as robotic assistance, augmented reality, or advanced biomaterials. Variations could include adapting the system for different medical procedures or applications, such as cardiovascular or neurological interventions.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the medical device industry, particularly in the fields of interventional pulmonology, oncology, and cardiology. The system's ability to provide real-time analysis, remote monitoring, and customized sampling devices could revolutionize the diagnostic and therapeutic landscape, offering improved patient outcomes and reduced healthcare costs.

CPC Classifications

SectionClassGroup
A A61 A61B8/445
A A61 A61B1/00066
A A61 A61B1/00135
A A61 A61B1/00137
A A61 A61B1/018
A A61 A61B1/0125
A A61 A61B1/2676
A A61 A61B8/12
A A61 A61B8/4494
A A61 A61M25/0026
A A61 A61M25/0136
A A61 A61M2025/0037

Field of Art

Medical device engineering, specifically interventional medical imaging and diagnostic catheter technologies, with expertise in ultrasound-guided sampling systems, endoscopic instrumentation, and minimally invasive medical device design

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device designer with advanced degrees in bioengineering or medical technology, experienced in catheter design, ultrasound imaging technologies, and minimally invasive diagnostic techniques, familiar with integrating electronic and sensing technologies into medical devices

Obviousness Rationale

A person having ordinary skill in the art would recognize that the PTD's integration of advanced digital technologies with the fundamental dual-lumen catheter design represents a predictable application of known technological enhancement strategies. The source patent establishes a core catheter architecture that naturally invites technological augmentation through digital sensing, data management, and adaptive manufacturing techniques. The proposed variations represent logical extensions of existing medical device innovation paradigms, utilizing well-established technological domains to incrementally improve diagnostic capabilities.

Obvious Combinations & Variations

Source Patent Element
Dual-lumen catheter design with imaging probe trench and secondary lumen
PTD Variation
Integration of AI-driven image analysis and blockchain data storage for ultrasound image processing
Obviousness Reasoning
A PHOSITA would find it obvious to augment medical imaging devices with computational analysis and secure data management, as these are standard practices in modern medical technology development
Source Patent Element
Catheter configured for endoscopic insertion with working channel compatibility
PTD Variation
IoT network integration for remote monitoring and control of catheter positioning
Obviousness Reasoning
Remote monitoring of medical devices is a predictable technological enhancement, particularly for precision diagnostic instruments where real-time tracking provides clinical value
Source Patent Element
Medical device designed for tissue interaction and imaging
PTD Variation
Nanomaterial-based surface coating and MEMS sensor integration for enhanced performance
Obviousness Reasoning
Surface modification and embedded sensing are well-established techniques for improving medical device functionality, representing a known approach to incremental device improvement
Source Patent Element
Catheter with configurable geometric design for medical imaging
PTD Variation
3D printing module for creating customized sampling devices based on AI-analyzed imaging data
Obviousness Reasoning
Adaptive manufacturing techniques combined with computational analysis represent a predictable technological convergence in medical device design
Source Patent Element
Ultrasound-guided tissue sampling catheter
PTD Variation
Machine learning algorithms for trajectory prediction and optimal sampling location identification
Obviousness Reasoning
Computational guidance of medical procedures is a foreseeable application of machine learning technologies in diagnostic medical devices
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857365 and the disclosed technological variations, a person having ordinary skill in the art would find the proposed medical device innovations obvious and lacking inventive distinctiveness. The incremental technological enhancements represented in this publication constitute prima facie obviousness under 35 U.S.C. ยง 103, rendering potential patent claims covering similar technological integrations anticipated and unpatentable.

Original Patent Information

Patent NumberUS 11,857,365
TitleDual lumen catheter
Assignee(s)OLYMPUS MEDICAL SYSTEMS CORP.