Advanced Real-time Ultrasound-Guided Peripheral Lung Tumor Sampling System

Publication ID: 24-11857365_0005_PTD

Published: October 28, 2025

Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Advanced Real-time Ultrasound-Guided Peripheral Lung Tumor Sampling System,” Published Technical Disclosure No. 24-11857365_0005_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857365_0005_PTD

This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,365.

Summary of the Inventive Concept

A next-generation system for ultrasound-guided peripheral lung tumor sampling, featuring adaptive catheters, real-time feedback, and advanced navigation capabilities to enhance diagnostic accuracy and patient safety.

Background and Problem Solved

The original dual lumen catheter patent, while innovative, has limitations in its range of motion and diagnostic capabilities. The new inventive concept addresses these limitations by introducing advanced features such as dynamically adjustable lumen diameters, shape-memory alloy catheters, and real-time feedback systems to provide more accurate and efficient sampling procedures.

Detailed Description of the Inventive Concept

The new system comprises a bronchoscope with an insertion tube, a radial ultrasound system, and a novel, adaptive catheter with dynamically adjustable lumen diameters. The catheter is configured to receive a medical device and an imaging probe, and the signal processor and display device provide real-time feedback to the healthcare professional during the sampling procedure. The system also includes advanced navigation capabilities, such as modular catheter components and machine learning-based algorithms for predicting optimal catheter trajectories. Additionally, a robotic system can be integrated to enable autonomous catheter navigation.

Novelty and Inventive Step

The new claims introduce significant advancements over the original patent, including the use of shape-memory alloy catheters, dynamically adjustable lumen diameters, and real-time feedback systems. These features enable more accurate and efficient sampling procedures, and the integration of advanced navigation capabilities and robotic systems further enhance the system's capabilities.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different materials for the catheter, such as polymers or ceramics, or the integration of additional sensors or imaging modalities. Variations of the system could also be designed for use in other medical procedures, such as cardiovascular or neurovascular interventions.

Potential Commercial Applications and Market

The advanced real-time ultrasound-guided peripheral lung tumor sampling system has significant commercial potential in the medical device industry, particularly in the fields of pulmonology, oncology, and radiology. The system's enhanced diagnostic accuracy and patient safety features could lead to increased adoption and market share in these industries.

CPC Classifications

Section	Class	Group
A	A61	A61B8/445
A	A61	A61B1/00066
A	A61	A61B1/00135
A	A61	A61B1/00137
A	A61	A61B1/018
A	A61	A61B1/0125
A	A61	A61B1/2676
A	A61	A61B8/12
A	A61	A61B8/4494
A	A61	A61M25/0026
A	A61	A61M25/0136
A	A61	A61M2025/0037

Section 103 Obviousness Analysis (PHOSITA)

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Field of Art

Medical device engineering, specifically interventional pulmonology and endoscopic imaging systems, focusing on catheter design, ultrasound guidance, and minimally invasive diagnostic procedures

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device designer with expertise in catheter technologies, endoscopic systems, ultrasound imaging, and interventional medical procedures, holding advanced degrees in biomedical engineering or related fields

Obviousness Rationale

A PHOSITA would recognize that the PTD's variations represent predictable technological extensions of the source patent's dual-lumen catheter design, leveraging known techniques in medical device engineering to enhance diagnostic capabilities through adaptive materials, real-time feedback systems, and advanced navigation technologies.

Obvious Combinations & Variations

Source Patent Element

Dual-lumen catheter with first lumen configured to receive an imaging probe

PTD Variation

Shape-memory alloy catheter with dynamically adjustable lumen diameters and real-time feedback system

Obviousness Reasoning

A PHOSITA would find it obvious to modify the original catheter design using known shape-memory materials to create a more adaptive imaging system, as material selection and dynamic configurability are standard design approaches in medical device engineering

Source Patent Element

Catheter configured to be slidably received within an endoscope's working channel

PTD Variation

Modular catheter with interchangeable lumen components for different medical devices and imaging probes

Obviousness Reasoning

Modular design is a predictable solution for increasing catheter versatility, representing a routine engineering optimization that a PHOSITA would readily conceive to expand the device's diagnostic capabilities

Source Patent Element

Catheter with multiple lumens for receiving medical devices and imaging probes

PTD Variation

Machine learning-based algorithm for predicting optimal catheter trajectories and robotic navigation system

Obviousness Reasoning

Integrating computational guidance with existing medical imaging technologies is a logical progression that a PHOSITA would find obvious, leveraging advances in machine learning and robotics to enhance diagnostic precision

Source Patent Element

Radial endobronchial ultrasound probe for peripheral lung tumor visualization

PTD Variation

Real-time feedback system with signal processor and display device providing dynamic procedural guidance

Obviousness Reasoning

Enhancing ultrasound imaging with real-time feedback is a predictable improvement that addresses known limitations in medical imaging, representing an obvious solution for a skilled practitioner

Source Patent Element

Guide sheath for extending diagnostic reach beyond bronchoscope

PTD Variation

Advanced navigation capabilities with patient-specific airway anatomy database and autonomous catheter manipulation

Obviousness Reasoning

Incorporating patient-specific data and autonomous navigation represents a natural technological progression that a PHOSITA would find obvious given existing imaging and diagnostic technologies

35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857365 and the disclosed technical variations, a person having ordinary skill in the art would find the claimed innovations obvious, as they represent predictable technological extensions utilizing known techniques in medical device design, imaging systems, and computational guidance, thereby rendering subsequent claims of novelty invalid under 35 U.S.C. § 103.

Original Patent Information

Patent Number	US 11,857,365
Title	Dual lumen catheter
Assignee(s)	OLYMPUS MEDICAL SYSTEMS CORP.