Advanced Multi-Frequency Harmonic Acoustography System for Enhanced Target Tissue Identification and Border Detection

Publication ID: 24-11857373_0001_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Advanced Multi-Frequency Harmonic Acoustography System for Enhanced Target Tissue Identification and Border Detection,” Published Technical Disclosure No. 24-11857373_0001_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857373_0001_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,373.

Summary of the Inventive Concept

This inventive concept presents a novel, high-performance multi-frequency harmonic acoustography system that significantly improves target tissue identification and border detection capabilities. The system integrates advanced technologies, including dynamically adjustable frequency differences, dual-mode transducers, real-time signal processing, adaptive filtering, and compact probe designs, to provide high-contrast images, enhanced target tissue characterization, and improved portability.

Background and Problem Solved

The original patent, 'Multi-frequency harmonic acoustography for target identification and border detection,' introduced a method for performing multi-frequency harmonic acoustography for target tissue identification and border detection within a target tissue. However, the original patent's limitations include fixed frequency differences, limited transducer capabilities, and lack of real-time signal processing. The new inventive concept addresses these limitations by introducing advanced features that significantly enhance the system's performance, usability, and versatility.

Detailed Description of the Inventive Concept

The advanced multi-frequency harmonic acoustography system comprises a focused confocal transducer with a dynamically adjustable frequency difference Δf, allowing for real-time optimization of target tissue identification and border detection. The system also features a dual-mode transducer capable of switching between high-frequency and low-frequency operation, enhancing target tissue characterization. A real-time signal processing module provides instantaneous feedback on target tissue properties during imaging, while an adaptive filtering technique suppresses background noise and enhances target tissue visibility. The system's compact, handheld probe design ensures enhanced portability and ease of use in clinical settings.

Novelty and Inventive Step

The new inventive concept's novelty lies in its integration of advanced features, including dynamically adjustable frequency differences, dual-mode transducers, real-time signal processing, adaptive filtering, and compact probe designs. These features, individually and collectively, provide a significant improvement over the original patent, offering enhanced performance, usability, and versatility.

Alternative Embodiments and Variations

Alternative embodiments of the advanced multi-frequency harmonic acoustography system could include variations in transducer design, such as using phased arrays or annular arrays, or incorporating additional features like Doppler ultrasound or elastography. The system could also be adapted for use in different clinical settings, such as cardiology or neurology, or integrated with other imaging modalities like MRI or CT.

Potential Commercial Applications and Market

The advanced multi-frequency harmonic acoustography system has significant commercial potential in the medical imaging industry, particularly in the fields of oncology, cardiology, and neurology. The system's enhanced performance, usability, and versatility make it an attractive solution for clinicians and researchers seeking to improve patient outcomes and advance medical research.

CPC Classifications

SectionClassGroup
A A61 A61B8/485
A A61 A61B8/085
A A61 A61B8/4494
B B06 B06B1/0622
G G01 G01S7/52038
G G01 G01S15/8913
G G01 G01S15/8922
G G01 G01S15/8952
A A61 A61B8/5207
G G01 G01S7/5203

Original Patent Information

Patent NumberUS 11,857,373
TitleMulti-frequency harmonic acoustography for target identification and border detection
Assignee(s)The Regents of the University of California