Next-Generation Vibro-Acoustography Platform for Personalized Medicine and Real-Time Tissue Analysis

Publication ID: 24-11857373_0005_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Next-Generation Vibro-Acoustography Platform for Personalized Medicine and Real-Time Tissue Analysis,” Published Technical Disclosure No. 24-11857373_0005_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857373_0005_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,373.

Summary of the Inventive Concept

A revolutionary vibro-acoustography platform that integrates hybrid transducers, machine learning-based signal processing, and cloud-based data analytics to enable real-time, label-free, and non-invasive tissue analysis and personalized medicine.

Background and Problem Solved

The original patent on multi-frequency harmonic acoustography for target identification and border detection has limitations in terms of resolution, speed, and clinical applicability. The new inventive concept addresses these limitations by introducing a hybrid transducer that combines acoustic and optical sensing, enabling real-time monitoring of tissue properties and personalized treatment plans.

Detailed Description of the Inventive Concept

The next-generation vibro-acoustography platform comprises a compact, wearable transducer array that emits and detects acoustic waves, a hybrid transducer incorporating a piezoelectric element and an optical sensor, and a machine learning-based signal processor. The platform can generate high-resolution, multi-frequency images of target tissues and provide real-time feedback on changes in tissue properties. The cloud-based database of tissue properties and machine learning-based algorithm enable personalized treatment plans and real-time monitoring of treatment efficacy.

Novelty and Inventive Step

The new claims introduce a paradigm shift in vibro-acoustography by combining acoustic and optical sensing, enabling real-time monitoring of tissue properties, and integrating machine learning-based signal processing and cloud-based data analytics. These advancements provide a significant improvement over the original patent, enabling personalized medicine and real-time tissue analysis.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different types of sensors, such as electromagnetic or thermal sensors, or the integration of other imaging modalities, such as ultrasound or MRI. Variations of the platform could be designed for specific clinical applications, such as cancer diagnosis or cardiovascular disease monitoring.

Potential Commercial Applications and Market

The next-generation vibro-acoustography platform has significant commercial potential in the fields of personalized medicine, medical imaging, and healthcare analytics. The platform could be marketed to hospitals, research institutions, and pharmaceutical companies, with potential applications in cancer diagnosis, cardiovascular disease monitoring, and neurodegenerative disease research.

CPC Classifications

SectionClassGroup
A A61 A61B8/485
A A61 A61B8/085
A A61 A61B8/4494
B B06 B06B1/0622
G G01 G01S7/52038
G G01 G01S15/8913
G G01 G01S15/8922
G G01 G01S15/8952
A A61 A61B8/5207
G G01 G01S7/5203

Original Patent Information

Patent NumberUS 11,857,373
TitleMulti-frequency harmonic acoustography for target identification and border detection
Assignee(s)The Regents of the University of California