Next-Generation Nanocellulose-Based Implants for Bile Duct Repair
Legal Citation
Summary of the Inventive Concept
A system for repairing bile ducts using advanced nanocellulose-based implants with self-healing properties, personalized design, and integrated microfluidic systems, enabling more effective and sustainable treatments.
Background and Problem Solved
The original patent disclosed a medical implant based on nanocellulose for repairing bile ducts. However, the implant's structure and functionality were limited, and its production process was not adaptable to individual patients' needs. The new inventive concept addresses these limitations by introducing self-healing properties, personalized design, and integrated microfluidic systems, enabling more effective and sustainable treatments.
Detailed Description of the Inventive Concept
The next-generation nanocellulose-based implant comprises a self-healing property, allowing it to adapt to changes in the bile duct over time. The implant's design is personalized using artificial intelligence, taking into account a patient's specific anatomy. The implant's structure features a porous design, enabling the growth of new tissue, and a microfluidic system for delivering therapeutic agents to the implant site. The production process involves 3D printing, incorporating nanocellulose and other biomaterials. The system also includes a sensor for detecting changes in the implant's structure or function and a communication module for transmitting data to a remote monitoring station.
Novelty and Inventive Step
The new inventive concept introduces several novel features, including self-healing properties, personalized design, and integrated microfluidic systems, which are not present in the original patent. The use of artificial intelligence in designing customized implants and the incorporation of microfluidic systems for delivering therapeutic agents represent significant advancements in the field.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include using different types of biomaterials, such as biodegradable polymers or ceramics, in combination with nanocellulose. The microfluidic system could be replaced with other types of drug delivery systems, such as nanoparticles or liposomes. The sensor and communication module could be integrated into a wearable device or a mobile application, enabling patients to monitor their implant's performance remotely.
Potential Commercial Applications and Market
The next-generation nanocellulose-based implant has significant commercial potential in the medical device industry, particularly in the field of hepato-biliary surgery. The personalized design and self-healing properties of the implant could reduce the risk of complications and improve patient outcomes, making it an attractive solution for hospitals and healthcare providers. The market for bile duct repair devices is expected to grow significantly in the coming years, driven by an increasing incidence of bile duct injuries and lesions.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61F2/04 |
| A | A61 | A61L31/005 |
| A | A61 | A61L31/10 |
| A | A61 | A61L31/146 |
| A | A61 | A61F2002/041 |
| A | A61 | A61L2400/12 |
| A | A61 | A61L2420/08 |
| C | C08 | C08L1/02 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Biomedical engineering, specifically medical implants for soft tissue reconstruction, with expertise in biomaterials, nanocellulose fabrication, and surgical reconstruction techniques
Person of Ordinary Skill (PHOSITA) Profile
A biomedical engineer or materials scientist with advanced degrees, experience in tissue engineering, knowledge of biomaterial processing techniques, and familiarity with medical device design and fabrication methods
Obviousness Rationale
A person having ordinary skill would recognize that the PTD's disclosed variations represent predictable extensions of the source patent's nanocellulose implant technology, utilizing known biomedical engineering techniques to enhance the fundamental design of a microbial cellulose tube for bile duct repair. The proposed modifications leverage standard approaches in personalized medicine, advanced manufacturing, and integrated medical device technologies that would be readily apparent to a skilled practitioner in the field.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,405 |
|---|---|
| Title | Medical implant based on nanocellulose |
| Assignee(s) | UNIVERSITÄTSKLINIKUM JENA |