Adaptive Stent Graft Devices for Optimized Fluid Flow and Biocompatibility

Publication ID: 24-11857407_0010_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Adaptive Stent Graft Devices for Optimized Fluid Flow and Biocompatibility,” Published Technical Disclosure No. 24-11857407_0010_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857407_0010_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,407.

Summary of the Inventive Concept

The inventive concept envisions a next-generation stent graft device that adaptively adjusts its geometry in response to changes in bodily conduit morphology, optimizing fluid flow and minimizing the risk of tissue ingrowth. This paradigm shift enables personalized, real-time therapeutic interventions and sets a new standard for implantable medical devices.

Background and Problem Solved

The original patent for implantable intraluminal devices addressed the need for stent graft devices that can be implanted in bodily cavities, organs, and vessels. However, these devices often face limitations in terms of flexibility, tissue ingrowth, and fluid flow optimization. The new inventive concept tackles these limitations by introducing adaptive, modular, and biohybrid components that dynamically respond to changing physiological conditions.

Detailed Description of the Inventive Concept

The adaptive stent graft device comprises a modular, self-expanding framework that adjusts its geometry in response to changes in bodily conduit morphology. This is achieved through a network of sensors and actuators that collaborate to optimize fluid flow and detect potential complications. The device can be deployed through minimally invasive procedures and subsequently programmed to dynamically adjust its shape and fluid flow characteristics in response to real-time physiological feedback. Interchangeable, 3D-printed segments can be customized to accommodate unique anatomical features and adapt to changing physiological conditions over time. Furthermore, the integration of living tissue components with synthetic materials enables the device to actively promote tissue regeneration, mitigate inflammation, and enhance overall biocompatibility.

Novelty and Inventive Step

The new inventive concept's adaptive, modular, and biohybrid components, as well as its ability to dynamically respond to changing physiological conditions, represent a significant departure from the original patent's fixed, tubular design. The integration of real-time physiological feedback, 3D-printed segments, and living tissue components introduces a new level of sophistication and personalization in implantable medical devices.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include devices with varying levels of adaptivity, different sensor and actuator configurations, or alternative materials and manufacturing techniques. Variations could also include devices tailored to specific anatomical locations or patient populations, such as pediatric or geriatric patients.

Potential Commercial Applications and Market

The adaptive stent graft device has significant commercial potential in the medical device industry, particularly in the areas of cardiovascular, neurovascular, and peripheral vascular interventions. The device's ability to optimize fluid flow and minimize tissue ingrowth could reduce complications and improve patient outcomes, making it an attractive solution for healthcare providers and patients alike.

CPC Classifications

SectionClassGroup
A A61 A61F2/07
A A61 A61F2/04
A A61 A61F2/852
A A61 A61F2/88
A A61 A61F2/89
A A61 A61F2002/041
A A61 A61F2002/075
A A61 A61F2240/001
A A61 A61F2250/0065
Y Y10 Y10T29/49826

Field of Art

Medical Device Engineering, specifically Interventional Cardiology and Vascular Implant Design. Requires advanced knowledge of biomaterials, medical device fabrication, fluid dynamics, and minimally invasive surgical techniques. Typical educational background includes biomedical engineering, mechanical engineering, or medical device design with advanced degrees and clinical experience.

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device designer with expertise in stent and implantable device technologies, familiar with materials science, computational modeling, and adaptive medical device design principles. Possesses knowledge of current manufacturing techniques including 3D printing and sensor integration strategies.

Obviousness Rationale

A PHOSITA would recognize that the adaptive stent graft device represents a predictable evolution of existing intraluminal device technologies. The core structural elements from the source patent provide a foundational framework that can be naturally extended through known engineering techniques like sensor integration, modular design, and advanced manufacturing methods. The proposed variations represent incremental improvements that would be obvious to a skilled practitioner seeking to enhance medical device performance and patient outcomes.

Obvious Combinations & Variations

Source Patent Element
Helically arranged membranous strip with overlapped turns allowing fluid communication
PTD Variation
Dynamic geometry adjustment with sensor-enabled shape modification
Obviousness Reasoning
Predictable application of known control systems to existing stent design, representing a standard engineering approach to improving device responsiveness
Source Patent Element
Tubular medical device with fluid flow channels
PTD Variation
3D-printed modular segments with customizable anatomical adaptation
Obviousness Reasoning
Routine design optimization using emerging manufacturing technologies, representing a known technique for personalizing medical implants
Source Patent Element
Implantable intraluminal device with support members
PTD Variation
Integration of living tissue components with synthetic materials
Obviousness Reasoning
Established trend in biomedical engineering toward biohybrid materials, representing a predictable approach to enhancing device biocompatibility
Source Patent Element
Medical device configured for deployment through fluid flow channels
PTD Variation
Real-time physiological feedback system for dynamic device adjustment
Obviousness Reasoning
Application of standard control system principles to medical device design, representing an obvious extension of existing technological capabilities
Source Patent Element
Implantable tubular medical device with flexible membrane
PTD Variation
Sensor network for detecting and mitigating potential complications
Obviousness Reasoning
Logical implementation of monitoring technologies to improve device safety, representing a predictable enhancement in medical device engineering
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857407 and the disclosed technical variations, a person having ordinary skill in the art would find the claimed adaptive stent graft device embodiments obvious and anticipated. The proposed innovations represent straightforward combinations of known medical device design principles, manufacturing techniques, and sensor integration strategies that would be readily apparent to a skilled practitioner in the field of interventional medical device engineering.

Original Patent Information

Patent NumberUS 11,857,407
TitleImplantable intraluminal device
Assignee(s)W. L. Gore & Associates, Inc.