Next-Generation Prosthetic Heart Valve System with Adaptive and Self-Healing Properties

Publication ID: 24-11857411_0010_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Next-Generation Prosthetic Heart Valve System with Adaptive and Self-Healing Properties,” Published Technical Disclosure No. 24-11857411_0010_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857411_0010_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,411.

Summary of the Inventive Concept

A revolutionary prosthetic heart valve system that integrates advanced materials, sensors, and artificial intelligence to provide real-time monitoring, adaptive shape-memory properties, and self-healing capabilities, enhancing valve performance and patient outcomes.

Background and Problem Solved

The original patent disclosed a prosthetic heart valve with a pericardial sealing member, which, while effective, has limitations in terms of material durability, valve performance, and real-time monitoring. The new inventive concept addresses these limitations by introducing a bio-absorbable stent, self-healing leaflets, and integrated sensors for real-time monitoring, enabling more efficient and effective valve implantation and performance.

Detailed Description of the Inventive Concept

The next-generation prosthetic heart valve system comprises a bio-absorbable stent, a valvular structure with self-healing leaflets, and a perivalvular sealing member with integrated sensors for real-time monitoring of valve performance. The system also features adaptive shape-memory properties, allowing the valve to adjust to changes in blood flow and pressure. Additionally, the valve incorporates artificial intelligence for real-time optimization of valve performance. The system can be fabricated using 3D printing, enabling customized valves with patient-specific geometries.

Novelty and Inventive Step

The new inventive concept's novelty lies in the integration of advanced materials, sensors, and artificial intelligence, which enables real-time monitoring, adaptive shape-memory properties, and self-healing capabilities. The inventive step is the combination of these features, which provides a paradigm shift in prosthetic heart valve design and functionality.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include using different types of advanced materials, such as nanofibers or hybrid materials, or incorporating additional features, such as micro-electro-mechanical systems (MEMS) or patient-specific sensors. Variations could also include different valve geometries or configurations, such as a lattice-based frame or a self-organizing valvular structure.

Potential Commercial Applications and Market

The next-generation prosthetic heart valve system has significant commercial potential in the medical device industry, particularly in the areas of cardiovascular health and surgical interventions. The target market includes hospitals, clinics, and medical research institutions, with potential applications in valve replacement surgeries, minimally invasive procedures, and personalized medicine.

CPC Classifications

SectionClassGroup
A A61 A61F2/2409
A A61 A61F2/2415
A A61 A61F2/2418
A A61 A61L27/3625
A A61 A61L27/50
A A61 A61L27/56
A A61 A61F2/2427
A A61 A61F2230/0054
A A61 A61F2240/001
A A61 A61F2250/0063
A A61 A61F2250/0069
A A61 A61L2430/20

Field of Art

Cardiovascular medical devices, specifically prosthetic heart valve systems, involving biomaterials, implantable device design, and advanced medical engineering with expertise in materials science, biomedical engineering, and surgical interventional techniques

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device designer with advanced degree, 5-10 years experience in cardiovascular implant design, familiar with materials engineering, surgical implantation techniques, and emerging medical technologies

Obviousness Rationale

A PHOSITA would recognize that the PTD's proposed variations represent predictable extensions of existing prosthetic heart valve technologies, leveraging known design principles and emerging materials science techniques. The integration of sensors, adaptive materials, and AI optimization represents incremental improvements using standard engineering approaches. The core functional elements remain consistent with established prosthetic valve design paradigms, suggesting obvious technological progression.

Obvious Combinations & Variations

Source Patent Element
Radially collapsible annular frame with inflow and outflow ends
PTD Variation
Bio-absorbable stent with shape-memory properties and adaptive geometry
Obviousness Reasoning
Predictable design evolution using known biomaterial techniques, representing a routine materials substitution with expected functional equivalence
Source Patent Element
Pericardial tissue outer skirt for sealing
PTD Variation
Perivalvular sealing member with integrated sensors and micro-electro-mechanical systems
Obviousness Reasoning
Logical technological enhancement using standard sensor integration techniques, expanding standard sealing functionality with minimal inventive complexity
Source Patent Element
Suture-secured leaflet structure within prosthetic valve frame
PTD Variation
Self-healing leaflets with nanofiber reinforcement and AI-driven performance optimization
Obviousness Reasoning
Incremental improvement using known materials science techniques, representing a predictable application of emerging technological capabilities
Source Patent Element
Implantable prosthetic valve with radial expandability
PTD Variation
3D-printed customized valve with patient-specific geometries and integrated artificial intelligence
Obviousness Reasoning
Routine application of advanced manufacturing techniques to existing medical device design, representing a standard technological progression
Source Patent Element
Prosthetic valve with defined material thickness and configuration
PTD Variation
Hybrid material structure incorporating nanofibers and biocompatible nanomaterials
Obviousness Reasoning
Predictable materials science extension using known engineering approaches, representing an obvious technological refinement
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857411 and the disclosed technological variations, a person having ordinary skill in the art would find the proposed prosthetic heart valve system variations obvious and lacking inventive distinctiveness. The incremental technological enhancements represent predictable design progressions within the established cardiovascular medical device design domain, thereby rendering potential patent claims obvious and anticipatable by the presented prior art disclosure.

Original Patent Information

Patent NumberUS 11,857,411
TitlePericardial sealing member for prosthetic heart valve
Assignee(s)EDWARDS LIFESCIENCES CORPORATION