Adaptive Endoluminal Support Systems for Personalized Cardiovascular Care

Publication ID: 24-11857414_0010_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Adaptive Endoluminal Support Systems for Personalized Cardiovascular Care,” Published Technical Disclosure No. 24-11857414_0010_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857414_0010_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,414.

Summary of the Inventive Concept

This inventive concept envisions a next-generation endoluminal support structure that can dynamically adapt to a patient's unique physiology and anatomy in real-time, providing unprecedented personalized care for cardiovascular diseases.

Background and Problem Solved

The original patent described a repositionable endoluminal support structure, but it had limitations in terms of customization and real-time adaptability. The new inventive concept addresses these limitations by integrating sensors, AI algorithms, and micro-actuators to create a truly adaptive system that can respond to changing patient conditions.

Detailed Description of the Inventive Concept

The new inventive concept comprises a sensor array that continuously monitors physiological conditions within a patient's vessel, and a micro-actuator system that dynamically adjusts the support structure's geometry in response to real-time sensor data. The system can be integrated with artificial intelligence algorithms to generate customized support structure designs based on patient-specific data. The prosthetic valve can also be equipped with integrated sensors and AI-powered decision support, enabling autonomous adjustments to its shape and function. Furthermore, the system can be deployed using a minimally invasive procedure with a robotic catheter system featuring real-time imaging and navigation capabilities. The modular endoluminal support platform allows for interchangeable modules with distinct geometries and material properties, ensuring a high degree of customization and adaptability.

Novelty and Inventive Step

The new inventive concept introduces a paradigm shift in endoluminal support structures by incorporating real-time sensing, AI-driven customization, and micro-actuation. These features enable a level of adaptability and personalization that was not possible with the original patent, making the new inventive concept novel and non-obvious.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different sensor modalities, such as optical or acoustic sensors, or the integration of additional AI algorithms for predictive analytics. Variations of the modular platform could include different module geometries, materials, or surface coatings to accommodate specific patient needs or vessel anatomies.

Potential Commercial Applications and Market

The adaptive endoluminal support system has significant commercial potential in the cardiovascular device market, with potential applications in treating a range of cardiovascular diseases, including atherosclerosis, aneurysms, and heart valve disorders. The system's ability to provide personalized care could lead to improved patient outcomes, reduced healthcare costs, and increased market share for companies that adopt this technology.

CPC Classifications

SectionClassGroup
A A61 A61F2/2427
A A61 A61F2/24
A A61 A61F2/243
A A61 A61F2/2409
A A61 A61F2/2412
A A61 A61F2/2418
A A61 A61F2/2469
A A61 A61F2/844
A A61 A61F2/2421
A A61 A61F2/82
A A61 A61F2/94
A A61 A61F2210/0076
A A61 A61F2220/0041
A A61 A61F2220/0075
A A61 A61F2230/0054
A A61 A61F2230/0091
A A61 A61F2250/001
A A61 A61F2250/0004
Y Y10 Y10T29/49826

Field of Art

Interventional Cardiology and Medical Device Engineering, focusing on endoluminal support structures, prosthetic heart valves, and minimally invasive medical device technologies. Requires advanced knowledge of biomechanical engineering, sensor integration, and adaptive medical device design

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or interventional cardiologist with advanced degrees, expertise in medical device design, familiarity with catheter-based interventions, understanding of sensor technologies, and knowledge of AI applications in medical device customization

Obviousness Rationale

A PHOSITA would recognize that the PTD's proposed adaptive endoluminal support system represents a predictable extension of existing stent and prosthetic valve technologies. The integration of sensors, micro-actuators, and AI-driven customization are logical technological progressions given the increasing trend toward personalized medical interventions. The core mechanical and functional principles of the source patent provide a clear foundation for implementing these advanced adaptive features.

Obvious Combinations & Variations

Source Patent Element
Prosthetic heart valve frame with interconnected struts and movable configuration
PTD Variation
Dynamic micro-actuator system for real-time geometry adjustment of the support structure
Obviousness Reasoning
A PHOSITA would recognize that adding dynamic geometry adjustment is a predictable improvement to existing stent technologies, representing a known technique for enhancing medical device performance and patient outcomes
Source Patent Element
Catheter-based delivery system with pull wire actuation
PTD Variation
Robotic catheter system with real-time imaging and navigation capabilities
Obviousness Reasoning
Integrating advanced navigation technologies is an obvious technological progression for minimally invasive medical device deployment, representing a finite set of predictable enhancements to existing catheter technologies
Source Patent Element
Endoluminal support structure with defined frame geometry
PTD Variation
Modular platform with interchangeable modules and distinct geometries
Obviousness Reasoning
Developing modular medical device platforms is a well-known design strategy that allows for increased customization and adaptability, representing a standard approach in medical device engineering
Source Patent Element
Prosthetic heart valve with defined structural components
PTD Variation
AI-powered decision support system for autonomous shape and function adjustment
Obviousness Reasoning
Incorporating AI and sensor technologies into medical devices is a predictable technological evolution, representing a known technique for enhancing device intelligence and adaptive capabilities
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857414 and the disclosed technical variations, a Person Having Ordinary Skill In The Art would find the proposed adaptive endoluminal support system obvious and lacking inventive merit. The combination of known medical device technologies, sensor integration techniques, and AI-driven customization strategies represents a predictable technological progression that would be readily conceived by a skilled practitioner in the field of interventional cardiology and medical device engineering.

Original Patent Information

Patent NumberUS 11,857,414
TitleRepositionable endoluminal support structure and its applications
Assignee(s)Edwards Lifesciences CardiAQ LLC