Cryogenic Sample Preservation System

Publication ID: 24-11857458_0007_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Cryogenic Sample Preservation System,” Published Technical Disclosure No. 24-11857458_0007_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857458_0007_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,458.

Summary of the Inventive Concept

A novel application of the freezable insert device technology for cryogenic storage and preservation of biological samples, organs, and cells, enabling secure and controlled freezing and thawing processes.

Background and Problem Solved

The original patent focused on alleviating menopausal symptoms, but its core technology can be repurposed to address the limitations of current cryopreservation methods, which often result in sample degradation and loss. The new inventive concept leverages the freezable insert device's ability to maintain a stable temperature and control energy release to preserve the structural integrity of biological samples.

Detailed Description of the Inventive Concept

The Cryogenic Sample Preservation System comprises a freezable insert device adapted for cryogenic storage, with a freezable core assembly designed to preserve the sample's structural integrity during freezing. The system can be used for various biological samples, including tissues, organs, and cells. The device is cooled to a temperature of -20°C or lower, and the sample is inserted and frozen. The system can be integrated with a control system for monitoring and controlling the temperature, ensuring a stable and controlled freezing process.

Novelty and Inventive Step

The new claims introduce a novel application of the freezable insert device technology in the field of cryogenic preservation, providing a non-obvious solution to the limitations of current cryopreservation methods. The inventive step lies in adapting the device's core technology to address the specific challenges of cryogenic storage, ensuring the preservation of biological samples' structural integrity.

Alternative Embodiments and Variations

Alternative embodiments of the Cryogenic Sample Preservation System could include variations in the device's material composition, size, and shape to accommodate different types of biological samples. Additionally, the system could be integrated with advanced temperature control systems, sensors, and automation technologies to further enhance its performance and efficiency.

Potential Commercial Applications and Market

The Cryogenic Sample Preservation System has significant commercial potential in the life sciences and biotechnology industries, particularly in applications such as organ transplantation, cell therapy, and biological sample banking. The system's ability to ensure secure and controlled cryopreservation could revolutionize the way biological samples are stored and utilized, opening up new opportunities for research, development, and clinical applications.

CPC Classifications

SectionClassGroup
A A61 A61F7/12
A A61 A61L31/042
A A61 A61F13/34
A A61 A61F2007/005
A A61 A61F2007/0219
A A61 A61F2007/108
A A61 A61H23/02
A A61 A61H2205/087

Original Patent Information

Patent NumberUS 11,857,458
TitleFreezable insert device