Ultrasound-Enhanced Delivery of Substances Across Various Industries

Publication ID: 24-11857459_0007_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Ultrasound-Enhanced Delivery of Substances Across Various Industries,” Published Technical Disclosure No. 24-11857459_0007_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857459_0007_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,459.

Summary of the Inventive Concept

This inventive concept leverages the core technology of ultrasound-enhanced delivery to expand into new applications and use cases, including agricultural pesticides, wood treatment, heavy crude oil processing, animal nutrition, and industrial surface cleaning.

Background and Problem Solved

The original patent focused on ultrasound-enhanced delivery of drugs for ophthalmic care, but its limitations can be overcome by applying this technology to other industries. For instance, in agriculture, pesticide effectiveness is hindered by soil and plant barriers, while in wood treatment, fungal decay is a significant concern. Similarly, heavy crude oil's high viscosity hinders transportation, and animal nutrition is often limited by poor nutrient absorption. Industrial surface cleaning also faces challenges in removing stubborn contaminants. This inventive concept addresses these problems by adapting the ultrasound-enhanced delivery technology to these new domains.

Detailed Description of the Inventive Concept

The new claims describe systems and methods for utilizing ultrasound energy to enhance the delivery of substances in various industries. For example, in agriculture, an ultrasound-generating device is coupled to a pesticide applicator, increasing the penetration of the pesticide into the soil or plant tissue. In wood treatment, ultrasound energy is applied to the wood product in conjunction with a fungicidal agent to prevent decay. Similarly, in heavy crude oil processing, ultrasound energy reduces the viscosity of the crude oil, allowing for more efficient transportation. In animal nutrition, ultrasound energy increases the absorption of nutrients by the animal when applied to the feed in conjunction with a nutrient supplement. Finally, in industrial surface cleaning, ultrasound energy enhances the cleaning effectiveness of a solution when applied to a surface.

Novelty and Inventive Step

The new claims introduce a novel application of ultrasound-enhanced delivery technology, expanding its scope beyond ophthalmic care to address specific problems in diverse industries. The inventive step lies in recognizing the potential of this technology to overcome barriers and limitations in these new domains, and in designing systems and methods that effectively integrate ultrasound energy with the specific requirements of each industry.

Alternative Embodiments and Variations

Alternative embodiments of this inventive concept could include variations in ultrasound frequency, intensity, and duration tailored to specific industry needs. Additionally, different types of substances could be delivered using this technology, such as fertilizers, biocides, or coatings. Furthermore, the ultrasound-generating device could be integrated into existing equipment or designed as a standalone unit.

Potential Commercial Applications and Market

This inventive concept has significant commercial potential across multiple industries, including agriculture, wood treatment, heavy crude oil processing, animal nutrition, and industrial surface cleaning. The market for these applications is substantial, with opportunities for partnerships, licensing, and product development.

CPC Classifications

SectionClassGroup
A A61 A61F9/0008
A A61 A61M37/0092
A A61 A61F2250/0093

Field of Art

Medical device technologies and ultrasound-based drug/substance delivery systems, with expertise in biomedical engineering, medical device design, and ultrasonic energy applications across biological and industrial interfaces

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device specialist with advanced degree, understanding of ultrasound physics, drug delivery mechanisms, and cross-disciplinary technology transfer principles, capable of adapting core technological concepts to novel application domains

Obviousness Rationale

The source patent's fundamental ultrasound-enhanced delivery mechanism represents a generalizable technological approach that can be systematically translated across different substance delivery contexts. A PHOSITA would recognize that the core principle of using ultrasonic energy to enhance penetration and absorption is fundamentally consistent whether applied to ocular drug delivery or agricultural pesticide distribution. The technical elements of ultrasound generation, coupling, and targeted energy application are sufficiently universal that their adaptation to alternative domains represents a predictable engineering variation.

Obvious Combinations & Variations

Source Patent Element
Ultrasound transducer configured for precise energy delivery to a targeted biological interface
PTD Variation
Applying ultrasound transducer to agricultural pesticide penetration and soil interface
Obviousness Reasoning
Known technique of modulating ultrasonic energy parameters to enhance substance permeation, representing a predictable engineering adaptation across biological systems
Source Patent Element
Drug receiving space with configurable coupling surface for targeted delivery
PTD Variation
Adapting coupling interface for wood treatment fungicidal agent application
Obviousness Reasoning
Systematic translation of surface coupling principles from medical device domain to materials treatment, utilizing established ultrasound energy transmission techniques
Source Patent Element
Signal generating unit operationally connected to ultrasound transducer
PTD Variation
Integrating ultrasound generator with crude oil pipeline viscosity reduction system
Obviousness Reasoning
Applying known ultrasonic energy modulation principles to fluid dynamics, representing a straightforward technological extension
Source Patent Element
Controller managing ultrasound energy parameters for precise delivery
PTD Variation
Implementing variable ultrasound frequency control for nutrient absorption in animal feed
Obviousness Reasoning
Predictable application of energy modulation techniques across biological absorption contexts, representing a design choice within ordinary skill
Source Patent Element
Sealed drug receiving space allowing substance permeation
PTD Variation
Creating ultrasound-enhanced cleaning solution interface for industrial surface treatment
Obviousness Reasoning
Systematic translation of substance transmission principles from medical to industrial domain, representing an obvious technological adaptation
35 U.S.C. § 103 Summary: Based on US Patent 11857459's fundamental ultrasound-enhanced delivery methodology, the present publication demonstrates that a Person Having Ordinary Skill In The Art would find the disclosed cross-domain applications of ultrasonic substance delivery inherently obvious, thereby establishing robust prior art against potential future patent claims seeking to monopolize these technological adaptations.

Original Patent Information

Patent NumberUS 11,857,459
TitleSystem and method for ultrasound-enhanced delivery of drugs
Assignee(s)SONIKURE HOLDINGS LIMITED