Personalized Ultrasound-Enhanced Drug Delivery System with AI, IoT, and Blockchain Integration

Publication ID: 24-11857459_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Personalized Ultrasound-Enhanced Drug Delivery System with AI, IoT, and Blockchain Integration,” Published Technical Disclosure No. 24-11857459_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857459_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,459.

Summary of the Inventive Concept

A novel system that integrates AI, IoT, and blockchain technologies to optimize ultrasound-enhanced drug delivery, ensuring personalized treatment, real-time monitoring, and secure supply chain management.

Background and Problem Solved

The original patent for ultrasound-enhanced delivery of drugs has limitations in terms of personalized treatment and supply chain management. The new inventive concept addresses these limitations by integrating AI, IoT, and blockchain technologies to create a more efficient, secure, and personalized system.

Detailed Description of the Inventive Concept

The new system consists of an AI-powered ultrasound transducer that generates tailored ultrasound waves based on a patient's eye anatomy, an IoT-enabled sensor that monitors eye pressure and temperature, a blockchain-enabled drug tracking module that verifies the authenticity and origin of the delivered drugs, and a machine learning-based controller that optimizes the ultrasound frequency and power based on real-time feedback. The system also includes a nanomaterial-based drug applicator, an AI-powered diagnostic module, and a cloud-based data analytics platform. The inventive concept enables real-time monitoring, personalized treatment, and secure supply chain management.

Novelty and Inventive Step

The new claims introduce the novel integration of AI, IoT, and blockchain technologies with ultrasound-enhanced drug delivery, providing a synergistic combination that significantly improves the original patent's limitations. The inventive step lies in the combination of these distinct technologies to create a more efficient, secure, and personalized system.

Alternative Embodiments and Variations

Alternative embodiments could include using different AI algorithms, IoT sensors, or blockchain platforms. Variations could also include integrating additional technologies, such as augmented reality or 5G networks, to further enhance the system's capabilities.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the ophthalmic care industry, particularly in the treatment of diseases such as central retinal vein occlusion, branch retinal vein occlusion, and age-related macular degeneration. The system's ability to provide personalized treatment, real-time monitoring, and secure supply chain management makes it an attractive solution for healthcare providers and patients alike.

CPC Classifications

SectionClassGroup
A A61 A61F9/0008
A A61 A61M37/0092
A A61 A61F2250/0093

Original Patent Information

Patent NumberUS 11,857,459
TitleSystem and method for ultrasound-enhanced delivery of drugs
Assignee(s)SONIKURE HOLDINGS LIMITED