Personalized Ocular Therapy Systems

Publication ID: 24-11857461_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Personalized Ocular Therapy Systems,” Published Technical Disclosure No. 24-11857461_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857461_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,461.

Summary of the Inventive Concept

A novel lacrimal system integrating AI, IoT, blockchain, and nanomaterials to provide targeted, data-driven, and secure drug delivery to the eye, addressing unmet needs in ocular disease management.

Background and Problem Solved

The original lacrimal system patent addressed challenges in drug delivery to the eye, but limitations in personalized treatment, data security, and real-time monitoring hindered its effectiveness. The new inventive concept combines the lacrimal system with cutting-edge technologies to overcome these limitations, providing a more comprehensive and efficient solution for ocular disease management.

Detailed Description of the Inventive Concept

The inventive concept integrates the lacrimal system device with an AI-powered diagnostic module for identifying ocular diseases, a blockchain-based secure data storage for storing patient medical records, and an IoT-enabled sensor for monitoring eye health. The system utilizes a nanomaterial-enhanced coating for controlled release of active agents and a micro-needle array for minimally invasive insertion into the eye. The wearable device with an integrated AI-powered assistant reminds patients to administer medication, and the cloud-based platform enables remote monitoring and analytics.

Novelty and Inventive Step

The new claims introduce the synergistic combination of AI, IoT, blockchain, and nanomaterials with the lacrimal system, providing a novel and non-obvious solution for personalized ocular therapy. The integration of these technologies enables real-time monitoring, data-driven treatment, and secure data storage, which are not present in the original patent.

Alternative Embodiments and Variations

Alternative embodiments may include the use of different AI algorithms, varying IoT sensor configurations, or alternative blockchain platforms. The inventive concept could also be adapted for use in other areas of medicine, such as respiratory or dermatological disease management.

Potential Commercial Applications and Market

The personalized ocular therapy system has significant commercial potential in the ocular disease management market, with potential applications in pharmaceutical companies, medical device manufacturers, and healthcare providers. The system's ability to provide targeted, data-driven, and secure treatment could lead to improved patient outcomes, reduced healthcare costs, and increased market share.

CPC Classifications

SectionClassGroup
A A61 A61F9/00772
A A61 A61F9/0017
A A61 A61M37/00
A A61 A61M31/002

Field of Art

Medical device technology focused on ocular drug delivery systems, encompassing biomedical engineering, medical device design, pharmaceutical delivery mechanisms, and digital health technologies

Person of Ordinary Skill (PHOSITA) Profile

A biomedical engineer or medical device designer with expertise in drug delivery systems, familiarity with IoT and AI technologies, understanding of medical device integration, and knowledge of emerging digital health platforms

Obviousness Rationale

A PHOSITA would recognize that integrating digital technologies with existing medical device architectures represents a predictable evolution of drug delivery systems. The source patent's lacrimal system provides a foundational platform that naturally invites technological augmentation through sensor, AI, and data management technologies. The proposed variations represent logical extensions of existing medical device design principles, utilizing well-established technological integration strategies.

Obvious Combinations & Variations

Source Patent Element
Lacrimal system with reservoir balloon for drug delivery
PTD Variation
Adding IoT-enabled sensor for monitoring eye health and dynamically adjusting fluid flow
Obviousness Reasoning
Integrating real-time monitoring sensors with drug delivery devices is a known technique in medical device design, representing a predictable application of sensor technologies to improve treatment precision
Source Patent Element
Drug delivery system with active pharmaceutical agents
PTD Variation
Implementing AI-powered diagnostic module for identifying ocular diseases and personalizing drug delivery
Obviousness Reasoning
Applying machine learning and diagnostic algorithms to medical device functionality is a well-established approach for enhancing treatment personalization and efficacy
Source Patent Element
Lacrimal system for targeted drug administration
PTD Variation
Incorporating nanomaterial-enhanced coating for controlled release of active agents
Obviousness Reasoning
Advanced material science techniques for modifying drug release profiles represent a standard approach in pharmaceutical delivery system optimization
Source Patent Element
Medical device for ocular treatment
PTD Variation
Blockchain-based secure data storage for patient medical records
Obviousness Reasoning
Implementing secure data management technologies is a predictable solution for addressing patient privacy and medical record management challenges
Source Patent Element
Fluid delivery system with reservoir and exit port
PTD Variation
Cloud-based platform for remote monitoring and treatment analytics
Obviousness Reasoning
Extending medical devices with digital monitoring and analytics platforms represents a standard approach in developing comprehensive healthcare technologies
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857461 and the disclosed technological variations, a person having ordinary skill in the art would find the proposed personalized ocular therapy system obvious and lacking inventive step. The combination of known medical device architectures with emerging digital health technologies represents a predictable and routine extension of existing drug delivery system design principles, thereby rendering potential patent claims obvious and unpatentable.

Original Patent Information

Patent NumberUS 11,857,461
TitleLacrimal system for drug delivery
Assignee(s)The Regents of the University of Colorado, a body corporate