Personalized Congenital Diarrhea Disorder Management Systems

Publication ID: 24-11857510_0005_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Personalized Congenital Diarrhea Disorder Management Systems,” Published Technical Disclosure No. 24-11857510_0005_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857510_0005_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,510.

Summary of the Inventive Concept

A next-generation approach to managing congenital diarrhea disorder, leveraging advanced technologies such as gene editing, personalized nutrition, and wearable devices to provide tailored treatment and prevention strategies.

Background and Problem Solved

The original patent, 'Methods and compositions for treating congenital diarrhea disorder,' demonstrated the efficacy of proanthocyanidin polymer compositions in treating diarrhea associated with congenital diarrhea disorder. However, this approach has limitations, including the need for parenteral nutrition and the lack of personalized treatment options. The new inventive concept addresses these limitations by introducing a suite of innovative solutions that integrate cutting-edge technologies to provide more effective and personalized management of congenital diarrhea disorder.

Detailed Description of the Inventive Concept

The new inventive concept encompasses a range of innovative solutions, including a system for personalized gut microbiome modulation, a method for predicting the likelihood of developing congenital diarrhea disorder, a wearable device for monitoring and managing the disorder, a personalized nutrition and supplementation plan, and a method for gene editing in stem cells to correct genetic mutations associated with the disorder. These solutions leverage advanced technologies such as probiotics, gene editing, and wearable devices to provide tailored treatment and prevention strategies. For example, the system for personalized gut microbiome modulation uses a probiotic composition tailored to the subject's specific gut microbiome profile, administered in a synergistic manner with a proanthocyanidin polymer composition to enhance efficacy. The wearable device for monitoring and managing congenital diarrhea disorder in infants tracks changes in stool consistency and frequency, providing valuable insights for healthcare providers.

Novelty and Inventive Step

The new claims introduce a paradigm shift in the management of congenital diarrhea disorder, moving from a one-size-fits-all approach to personalized, tailored solutions that integrate advanced technologies. The inventive concept's novelty lies in its ability to combine cutting-edge technologies to provide a comprehensive management system, addressing the limitations of the original patent and providing a more effective and sustainable approach to treating congenital diarrhea disorder.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of artificial intelligence and machine learning algorithms to analyze gut microbiome data and predict disease susceptibility, or the development of implantable devices for continuous monitoring and management of congenital diarrhea disorder. Variations could include the use of different types of probiotics or gene editing technologies, or the integration of additional sensors and data analytics modules into the wearable device.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the healthcare industry, particularly in the areas of pediatrics and gastroenterology. The market for congenital diarrhea disorder management solutions is expected to grow as the prevalence of the disorder increases, and the inventive concept's personalized and tailored approach is likely to appeal to healthcare providers and patients seeking more effective and sustainable treatment options.

CPC Classifications

SectionClassGroup
A A61 A61K31/353
A A61 A61K9/0095
A A61 A61K9/28
A A61 A61K9/48
A A61 A61P1/04
A A61 A61P1/12

Original Patent Information

Patent NumberUS 11,857,510
TitleMethods and compositions for treating congenital diarrhea disorder
Assignee(s)NAPO PHARMACEUTICALS, INC.