Personalized Congenital Diarrhea Disorder Management Systems
Legal Citation
Summary of the Inventive Concept
A next-generation approach to managing congenital diarrhea disorder, leveraging advanced technologies such as gene editing, personalized nutrition, and wearable devices to provide tailored treatment and prevention strategies.
Background and Problem Solved
The original patent, 'Methods and compositions for treating congenital diarrhea disorder,' demonstrated the efficacy of proanthocyanidin polymer compositions in treating diarrhea associated with congenital diarrhea disorder. However, this approach has limitations, including the need for parenteral nutrition and the lack of personalized treatment options. The new inventive concept addresses these limitations by introducing a suite of innovative solutions that integrate cutting-edge technologies to provide more effective and personalized management of congenital diarrhea disorder.
Detailed Description of the Inventive Concept
The new inventive concept encompasses a range of innovative solutions, including a system for personalized gut microbiome modulation, a method for predicting the likelihood of developing congenital diarrhea disorder, a wearable device for monitoring and managing the disorder, a personalized nutrition and supplementation plan, and a method for gene editing in stem cells to correct genetic mutations associated with the disorder. These solutions leverage advanced technologies such as probiotics, gene editing, and wearable devices to provide tailored treatment and prevention strategies. For example, the system for personalized gut microbiome modulation uses a probiotic composition tailored to the subject's specific gut microbiome profile, administered in a synergistic manner with a proanthocyanidin polymer composition to enhance efficacy. The wearable device for monitoring and managing congenital diarrhea disorder in infants tracks changes in stool consistency and frequency, providing valuable insights for healthcare providers.
Novelty and Inventive Step
The new claims introduce a paradigm shift in the management of congenital diarrhea disorder, moving from a one-size-fits-all approach to personalized, tailored solutions that integrate advanced technologies. The inventive concept's novelty lies in its ability to combine cutting-edge technologies to provide a comprehensive management system, addressing the limitations of the original patent and providing a more effective and sustainable approach to treating congenital diarrhea disorder.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include the use of artificial intelligence and machine learning algorithms to analyze gut microbiome data and predict disease susceptibility, or the development of implantable devices for continuous monitoring and management of congenital diarrhea disorder. Variations could include the use of different types of probiotics or gene editing technologies, or the integration of additional sensors and data analytics modules into the wearable device.
Potential Commercial Applications and Market
The inventive concept has significant commercial potential in the healthcare industry, particularly in the areas of pediatrics and gastroenterology. The market for congenital diarrhea disorder management solutions is expected to grow as the prevalence of the disorder increases, and the inventive concept's personalized and tailored approach is likely to appeal to healthcare providers and patients seeking more effective and sustainable treatment options.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K31/353 |
| A | A61 | A61K9/0095 |
| A | A61 | A61K9/28 |
| A | A61 | A61K9/48 |
| A | A61 | A61P1/04 |
| A | A61 | A61P1/12 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Medical biotechnology focusing on gastrointestinal disorders, specifically congenital diarrheal disorders (CDD), with expertise in pharmaceutical compositions, personalized medicine, and therapeutic interventions for pediatric patients
Person of Ordinary Skill (PHOSITA) Profile
A medical researcher or biotechnologist with advanced degree (PhD/MD), specialized knowledge in pediatric gastroenterology, familiarity with genetic disorders, proanthocyanidin therapies, and emerging personalized medicine technologies
Obviousness Rationale
A PHOSITA would recognize that the published technical disclosure represents a natural progression of the source patent's core therapeutic approach, extending the proanthocyanidin polymer treatment for congenital diarrheal disorders through predictable technological advancements in personalized medicine, genetic analysis, and monitoring technologies
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,510 |
|---|---|
| Title | Methods and compositions for treating congenital diarrhea disorder |
| Assignee(s) | NAPO PHARMACEUTICALS, INC. |