Synergistic Treatment Systems for Congenital Diarrheal Disorders

Publication ID: 24-11857510_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Treatment Systems for Congenital Diarrheal Disorders,” Published Technical Disclosure No. 24-11857510_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857510_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,510.

Summary of the Inventive Concept

The present invention combines proanthocyanidin polymer compositions with advanced technologies, such as AI, IoT, blockchain, and nanomaterials, to create a more effective and personalized treatment system for congenital diarrhea disorders.

Background and Problem Solved

Congenital Diarrheal Disorders (CDDs) are a group of inherited chronic enteropathies characterized by heterogeneous etiology. The original patent addressed the need for effective treatments using proanthocyanidin polymer compositions. However, the current invention takes a significant leap forward by integrating these compositions with cutting-edge technologies to provide a more comprehensive and adaptive treatment approach.

Detailed Description of the Inventive Concept

The inventive concept comprises four main components: 1) a proanthocyanidin polymer composition, 2) an artificial intelligence module for monitoring and adjusting dosage, 3) a blockchain-secured platform for genomic data analysis and personalized treatment planning, and 4) a nanomaterial-based delivery system for targeted enterocyte treatment. Additionally, the system may include IoT-enabled wearable devices for remote monitoring and machine learning algorithms for data integration and optimization.

Novelty and Inventive Step

The new claims introduce a synergistic combination of proanthocyanidin polymer compositions with AI, IoT, blockchain, and nanomaterials, which provides a non-obvious and innovative solution for treating congenital diarrhea disorders. The integration of these technologies enables real-time monitoring, personalized treatment, and targeted delivery, significantly improving treatment outcomes.

Alternative Embodiments and Variations

Alternative embodiments may include varying the type of nanomaterial used, incorporating additional data sources into the machine learning algorithm, or using different blockchain platforms for secure data storage. Variations may also include adapting the system for use in different disease indications or integrating with existing electronic health record systems.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the pharmaceutical and healthcare industries, particularly in the areas of rare genetic disorders and personalized medicine. The system's ability to provide real-time monitoring and adaptive treatment plans makes it an attractive solution for healthcare providers and patients alike.

CPC Classifications

SectionClassGroup
A A61 A61K31/353
A A61 A61K9/0095
A A61 A61K9/28
A A61 A61K9/48
A A61 A61P1/04
A A61 A61P1/12

Original Patent Information

Patent NumberUS 11,857,510
TitleMethods and compositions for treating congenital diarrhea disorder
Assignee(s)NAPO PHARMACEUTICALS, INC.