EGFR Mutation-Based Crop Monitoring and Control System
Legal Citation
Summary of the Inventive Concept
A novel system for monitoring and controlling crop growth by detecting EGFR mutations in plants, enabling targeted application of selective inhibitors to prevent tumor formation and improve crop yields.
Background and Problem Solved
The original patent disclosed a selective inhibitor of exon 20 insertion mutant EGFR for treating malignant lung tumors. However, this technology has limitations in its application scope, focusing solely on cancer treatment. The new inventive concept addresses the problem of crop tumor formation and yield reduction by leveraging the core technology of EGFR mutation detection and selective inhibition.
Detailed Description of the Inventive Concept
The EGFR mutation-based crop monitoring and control system consists of a sensor for detecting EGFR mutations in plants, a controller for applying a selective inhibitor to plants expressing EGFR mutations, and a composition for treating plant tumors. The system enables targeted application of the selective inhibitor, preventing tumor formation and improving crop yields. The method for improving crop yields involves detecting EGFR mutations in plants and applying the selective inhibitor to prevent tumor formation. The composition for treating plant tumors comprises a selective inhibitor of EGFR mutations and a carrier for delivering the inhibitor to plant cells.
Novelty and Inventive Step
The new claims introduce a novel application of EGFR mutation detection and selective inhibition in the agricultural industry, providing a non-obvious solution to the problem of crop tumor formation and yield reduction. The inventive step lies in the adaptation of the original patent's technology to a new field, leveraging the core concept of EGFR mutation detection and selective inhibition to address a distinct problem.
Alternative Embodiments and Variations
Alternative embodiments of the inventive concept could include the use of different types of sensors or detection methods, varying compositions for treating plant tumors, or integration with existing agricultural systems. Variations could also involve adapting the system for use in different types of crops or agricultural settings.
Potential Commercial Applications and Market
The EGFR mutation-based crop monitoring and control system has significant commercial potential in the agricultural industry, particularly in the context of precision agriculture and crop yield improvement. The target market includes agricultural companies, farmers, and researchers seeking to improve crop yields and reduce crop losses due to tumor formation.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K31/519 |
| A | A61 | A61P35/00 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Molecular biology and biotechnology, specifically focused on targeted therapeutic interventions involving EGFR mutations and selective inhibition across biological systems
Person of Ordinary Skill (PHOSITA) Profile
A researcher with advanced degree in molecular biology, biotechnology, or related field, possessing expertise in genetic mutation analysis, receptor inhibition techniques, and cross-disciplinary technology transfer
Obviousness Rationale
A PHOSITA would recognize the fundamental similarity between cancer treatment and plant tumor prevention strategies, particularly in the context of EGFR mutation detection and targeted inhibition. The core technological principle of identifying specific genetic mutations and applying selective inhibitors represents a transferable approach across biological domains. The systematic methodology of mutation detection followed by targeted intervention is a well-established paradigm in molecular biology that naturally extends across different biological systems.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,513 |
|---|---|
| Title | Selective inhibitor of exon 20 insertion mutant EGFR |
| Assignee(s) | TAIHO PHARMACEUTICAL CO., LTD. |