EGFR Mutation-Based Crop Monitoring and Control System

Publication ID: 24-11857513_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “EGFR Mutation-Based Crop Monitoring and Control System,” Published Technical Disclosure No. 24-11857513_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857513_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,513.

Summary of the Inventive Concept

A novel system for monitoring and controlling crop growth by detecting EGFR mutations in plants, enabling targeted application of selective inhibitors to prevent tumor formation and improve crop yields.

Background and Problem Solved

The original patent disclosed a selective inhibitor of exon 20 insertion mutant EGFR for treating malignant lung tumors. However, this technology has limitations in its application scope, focusing solely on cancer treatment. The new inventive concept addresses the problem of crop tumor formation and yield reduction by leveraging the core technology of EGFR mutation detection and selective inhibition.

Detailed Description of the Inventive Concept

The EGFR mutation-based crop monitoring and control system consists of a sensor for detecting EGFR mutations in plants, a controller for applying a selective inhibitor to plants expressing EGFR mutations, and a composition for treating plant tumors. The system enables targeted application of the selective inhibitor, preventing tumor formation and improving crop yields. The method for improving crop yields involves detecting EGFR mutations in plants and applying the selective inhibitor to prevent tumor formation. The composition for treating plant tumors comprises a selective inhibitor of EGFR mutations and a carrier for delivering the inhibitor to plant cells.

Novelty and Inventive Step

The new claims introduce a novel application of EGFR mutation detection and selective inhibition in the agricultural industry, providing a non-obvious solution to the problem of crop tumor formation and yield reduction. The inventive step lies in the adaptation of the original patent's technology to a new field, leveraging the core concept of EGFR mutation detection and selective inhibition to address a distinct problem.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different types of sensors or detection methods, varying compositions for treating plant tumors, or integration with existing agricultural systems. Variations could also involve adapting the system for use in different types of crops or agricultural settings.

Potential Commercial Applications and Market

The EGFR mutation-based crop monitoring and control system has significant commercial potential in the agricultural industry, particularly in the context of precision agriculture and crop yield improvement. The target market includes agricultural companies, farmers, and researchers seeking to improve crop yields and reduce crop losses due to tumor formation.

CPC Classifications

SectionClassGroup
A A61 A61K31/519
A A61 A61P35/00

Original Patent Information

Patent NumberUS 11,857,513
TitleSelective inhibitor of exon 20 insertion mutant EGFR
Assignee(s)TAIHO PHARMACEUTICAL CO., LTD.