Synergistic Treatment System for Malignant Lung Tumors

Publication ID: 24-11857513_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Treatment System for Malignant Lung Tumors,” Published Technical Disclosure No. 24-11857513_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857513_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,513.

Summary of the Inventive Concept

A comprehensive system integrating AI, IoT, blockchain, and new materials to enhance treatment efficacy and patient outcomes for malignant lung tumors

Background and Problem Solved

The original patent disclosed a selective inhibitor of exon 20 insertion mutant EGFR for treating malignant lung tumors. However, it had limitations in detecting and analyzing EGFR mutations, predicting treatment efficacy, and ensuring secure data sharing. The new inventive concept addresses these limitations by integrating distinct technologies to create a more powerful system

Detailed Description of the Inventive Concept

The system comprises a genetic testing module, an AI-based analysis module, and a database for storing EGFR mutation information. The AI module predicts treatment efficacy based on the detected mutation and stored information. Additionally, the system includes an IoT-enabled sensor network for identifying potential therapeutic agents and a blockchain-based secure data sharing platform for analyzing genomic data. The system also features a nanoparticle-based delivery system for targeted delivery of the selective inhibitor, composed of a new material with enhanced biocompatibility and stability

Novelty and Inventive Step

The new inventive concept combines the selective inhibitor of exon 20 insertion mutant EGFR with AI, IoT, blockchain, and new materials to create a synergistic system that enhances treatment efficacy and patient outcomes. The integration of these distinct technologies is novel and non-obvious compared to the original patent

Alternative Embodiments and Variations

Alternative embodiments may include using different AI algorithms, IoT sensor networks, or blockchain platforms. Variations may include integrating additional technologies, such as machine learning or genomics platforms, to further enhance the system's capabilities

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the pharmaceutical and healthcare industries, particularly in the development of personalized treatment plans for malignant lung tumors

CPC Classifications

SectionClassGroup
A A61 A61K31/519
A A61 A61P35/00

Original Patent Information

Patent NumberUS 11,857,513
TitleSelective inhibitor of exon 20 insertion mutant EGFR
Assignee(s)TAIHO PHARMACEUTICAL CO., LTD.