Enhanced Branched Amino Acid Surfactants for Healthcare Products

Publication ID: 24-11857515_0001_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Branched Amino Acid Surfactants for Healthcare Products,” Published Technical Disclosure No. 24-11857515_0001_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857515_0001_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,515.

Summary of the Inventive Concept

This inventive concept introduces novel improvements to branched amino acid surfactants for healthcare products, enhancing their stability, bioavailability, and delivery efficiency.

Background and Problem Solved

The original patent for branched amino acid surfactants has limitations in terms of stability, delivery, and bioavailability. This new inventive concept addresses these limitations by introducing methods for preparing and stabilizing the surfactants, as well as enhancing their bioavailability and delivery efficiency.

Detailed Description of the Inventive Concept

The new claims include methods for preparing branched amino acid surfactants by mixing siloxane derivatives of amino acids with solvents and concentrating the solutions. Additionally, the inventive concept includes systems for delivering the surfactants to target sites in healthcare products, as well as compositions that enhance the bioavailability of bioactive agents. Furthermore, the inventive concept provides methods for enhancing the stability of the surfactants by adding stabilizing agents and storing the compositions at controlled temperatures. The inventive concept also includes branched amino acid surfactant compositions with pH-adjusting agents to maintain optimal pH levels.

Novelty and Inventive Step

The new claims provide a novel approach to preparing, stabilizing, and delivering branched amino acid surfactants, which is non-obvious compared to the original patent. The inventive concept's focus on enhancing bioavailability, stability, and delivery efficiency sets it apart from the original patent.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include different solvents, stabilizing agents, and pH-adjusting agents. Additionally, the inventive concept could be applied to various healthcare products, such as cosmetics, pharmaceuticals, and medical devices.

Potential Commercial Applications and Market

The enhanced branched amino acid surfactants have significant commercial potential in the healthcare industry, particularly in the development of more efficient and effective healthcare products. The target market includes pharmaceutical, cosmetic, and medical device companies seeking to improve the performance of their products.

CPC Classifications

SectionClassGroup
A A61 A61K47/183
A A61 A61K9/0019
A A61 A61K9/08
A A61 A61K9/107
A A61 A61K31/5377
A A61 A61K31/55
A A61 A61K47/186
A A61 A61K47/20

Field of Art

Pharmaceutical and healthcare product formulation, specifically surfactant chemistry with a focus on amino acid-based surface-active compounds for drug delivery and healthcare applications

Person of Ordinary Skill (PHOSITA) Profile

A skilled practitioner with expertise in organic chemistry, pharmaceutical formulation, and surfactant design, holding at least a Master's degree or equivalent professional experience in chemical engineering or pharmaceutical sciences

Obviousness Rationale

The Published Technical Disclosure presents incremental modifications to the source patent's branched amino acid surfactants that would be readily apparent to a person skilled in the art. The PTD's variations represent predictable extensions of known surfactant design principles, utilizing standard pharmaceutical formulation techniques to enhance delivery, stability, and bioavailability of existing surfactant technologies.

Obvious Combinations & Variations

Source Patent Element
Siloxane derivatives of amino acids with surface-active properties for healthcare formulations
PTD Variation
Adding pH-adjusting agents to maintain composition pH between 5.5 and 7.5
Obviousness Reasoning
Adjusting pH is a standard formulation technique to optimize surfactant performance and stability, which would be an obvious design choice for a skilled formulation chemist
Source Patent Element
Healthcare formulations using surfactants as delivery mechanisms
PTD Variation
Developing a controlled-release delivery system with a specialized container and dispenser
Obviousness Reasoning
Controlled-release mechanisms are well-known in pharmaceutical formulation, representing a predictable solution for improving drug delivery efficiency
Source Patent Element
Branched amino acid surfactants with potential for healthcare applications
PTD Variation
Adding stabilizing agents and implementing controlled temperature storage
Obviousness Reasoning
Enhancing surfactant stability through standard preservation techniques is a routine optimization strategy in pharmaceutical chemistry
Source Patent Element
Basic surfactant composition with potential for bioactive agent delivery
PTD Variation
Demonstrating enhanced bioavailability of bioactive agents by at least 20%
Obviousness Reasoning
Improving drug delivery efficiency through surfactant modification is a predictable and expected approach in pharmaceutical formulation
Source Patent Element
Siloxane derivative surfactants in healthcare products
PTD Variation
Developing solvent-based concentration methods for surfactant preparation
Obviousness Reasoning
Solvent concentration techniques are standard chemical engineering practices for creating concentrated surfactant compositions
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857515 and the subsequent Published Technical Disclosure, a person having ordinary skill in the art would find the claimed variations to be obvious extensions of existing surfactant technology. The incremental improvements in delivery, stability, and formulation represent predictable solutions within the established knowledge of pharmaceutical surfactant design, thereby rendering potential patent claims obvious under 35 U.S.C. Section 103.

Original Patent Information

Patent NumberUS 11,857,515
TitleBranched amino acid surfactants for use in healthcare products
Assignee(s)AdvanSix Resins & Chemicals LLC