Enhanced Telomerase-Activating Compounds for Fertility and Related Applications

Publication ID: 24-11857516_0006_PTD
Published: October 28, 2025
Category:Direct Improvements & Enhancements

Legal Citation

pr1or.art Inc., “Enhanced Telomerase-Activating Compounds for Fertility and Related Applications,” Published Technical Disclosure No. 24-11857516_0006_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857516_0006_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,516.

Summary of the Inventive Concept

This inventive concept discloses improved telomerase-activating compounds and compositions for treating diseases, disorders, and conditions related to fertility and preserving same. The new claims provide enhanced formulations, dosing regimens, and combinations with fertility-promoting agents to optimize telomerase expression and activity, leading to better fertility outcomes.

Background and Problem Solved

The original patent disclosed telomerase-activating compounds for fertility and related applications, but had limitations in terms of optimizing telomerase expression, controlling dosing, and addressing individual variability. The new inventive concept addresses these limitations by introducing controlled-release formulations, personalized dosing regimens, and combinations with antioxidants and fertility-promoting agents.

Detailed Description of the Inventive Concept

The new inventive concept comprises a system for enhancing fertility in a subject, featuring a telomerase-activating compound and a fertility-promoting agent. The telomerase-activating compound is administered in a controlled-release formulation to optimize telomerase expression and activity. Additionally, a method for improving fertility outcomes in a subject involves administering a telomerase-activating compound in a personalized dosage regimen based on the subject's individual telomerase expression profile. Furthermore, a composition for promoting fertility in a subject includes a telomerase-activating compound and an antioxidant, which enhances the bioavailability and efficacy of the telomerase-activating compound.

Novelty and Inventive Step

The new claims introduce novel combinations of telomerase-activating compounds with fertility-promoting agents, controlled-release formulations, and personalized dosing regimens, which are not obvious from the original patent. These improvements provide a significant enhancement to the original inventive concept, making it more effective and efficient.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include different formulations, such as oral, injectable, or topical, and various combinations of telomerase-activating compounds with other fertility-promoting agents. Additionally, the inventive concept could be adapted for use in other applications, such as cancer treatment or regenerative medicine.

Potential Commercial Applications and Market

The enhanced telomerase-activating compounds and compositions have significant commercial potential in the fertility and reproductive health markets, as well as in related industries such as cancer treatment and regenerative medicine. The target market includes pharmaceutical companies, biotechnology firms, and healthcare providers specializing in fertility and reproductive health.

CPC Classifications

SectionClassGroup
A A61 A61K31/09
A A61 A61K31/137
A A61 A61K31/4025
A A61 A61K31/4545
A A61 A61K31/5377
A A61 A61K31/66
A A61 A61P15/08

Original Patent Information

Patent NumberUS 11,857,516
TitleTelomerase activating compounds for use in fertility and related applications
Assignee(s)Neuromagen Pharma, Ltd.