Synergistic Combination of Compounds and Advanced Technologies for Enhanced Coronavirus Treatment

Publication ID: 24-11857517_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Combination of Compounds and Advanced Technologies for Enhanced Coronavirus Treatment,” Published Technical Disclosure No. 24-11857517_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857517_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,517.

Summary of the Inventive Concept

The present inventive concept integrates patented compounds for treating coronavirus infections with cutting-edge technologies like AI, IoT, blockchain, and nanomaterials to create a more effective and efficient system for combating coronavirus-associated diseases.

Background and Problem Solved

The original patent disclosed compounds for treating coronavirus infections, but the treatment outcomes can be improved by leveraging advanced technologies to enhance the compounds' efficacy, monitor patients more effectively, and ensure secure distribution. The present inventive concept addresses these limitations by introducing synergistic combinations of the patented compounds with AI, IoT, blockchain, and nanomaterials.

Detailed Description of the Inventive Concept

The inventive concept comprises a compound represented by Formula I, wherein R1-R6 are each independently selected from the group consisting of hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heteroalicyclic, and carbonyl. This compound is integrated with a machine learning module for predicting the efficacy of the compound in treating the disease, IoT sensors for monitoring the patient's vital signs, a blockchain-based platform for tracking the distribution and administration of the compound, and a nanomaterial for enhancing the compound's bioavailability. The machine learning module uses a deep learning model trained on a dataset of coronavirus-infected cells to predict the efficacy of the compound. The IoT sensors provide real-time monitoring of the patient's vital signs, enabling timely interventions. The blockchain-based platform ensures secure and transparent tracking of the compound's distribution and administration. The nanomaterial enhances the compound's bioavailability, leading to improved treatment outcomes.

Novelty and Inventive Step

The present inventive concept's novelty lies in the synergistic combination of the patented compounds with advanced technologies like AI, IoT, blockchain, and nanomaterials. The inventive step resides in the integration of these technologies to create a more effective and efficient system for combating coronavirus-associated diseases, which is not obvious from the original patent.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept may include using different machine learning algorithms, IoT sensor configurations, blockchain platforms, or nanomaterials. Variations may also include integrating the compound with other advanced technologies, such as robotics or augmented reality, to further enhance treatment outcomes.

Potential Commercial Applications and Market

The present inventive concept has significant commercial potential in the pharmaceutical and healthcare industries, particularly in the context of coronavirus pandemic management. The target market includes hospitals, clinics, and research institutions, as well as governments and public health organizations.

CPC Classifications

SectionClassGroup
A A61 A61K31/122
A A61 A61K9/0053
A A61 A61K9/0095
A A61 A61K9/127
A A61 A61K9/2009
A A61 A61K9/2013
A A61 A61K9/2018
A A61 A61K9/2054
A A61 A61K9/2095
A A61 A61K9/282
A A61 A61K9/2833
A A61 A61K9/4833
A A61 A61K9/4858
A A61 A61K9/4866
A A61 A61K31/198
A A61 A61K31/222
A A61 A61K31/381
A A61 A61K31/40
A A61 A61K31/422
A A61 A61K31/433
A A61 A61K31/454
A A61 A61K31/513
A A61 A61K31/536
A A61 A61K36/30
A A61 A61P31/14
A A61 A61K2236/51

Field of Art

Pharmaceutical chemistry and medical technologies, specifically focused on coronavirus treatment methods, drug delivery systems, and advanced medical technology integration. Requires expertise in organic chemistry, pharmacology, machine learning, IoT sensor technologies, and blockchain platforms

Person of Ordinary Skill (PHOSITA) Profile

A multidisciplinary professional with advanced degrees in pharmaceutical sciences, biotechnology, or medical engineering, possessing working knowledge of drug development, computational modeling, medical sensor technologies, and emerging digital health platforms

Obviousness Rationale

A PHOSITA would recognize that integrating advanced digital technologies with existing pharmaceutical compounds represents a predictable extension of state-of-the-art medical treatment strategies. The combination of machine learning prediction, IoT monitoring, blockchain tracking, and nanomaterial enhancement with established coronavirus treatment compounds follows a logical progression of technological convergence. These technological integrations represent incremental improvements that would be obvious to a skilled practitioner seeking to optimize treatment methodologies.

Obvious Combinations & Variations

Source Patent Element
Compound represented by Formula I for treating coronavirus infections
PTD Variation
Adding machine learning module to predict compound efficacy using deep learning models
Obviousness Reasoning
Applying computational predictive techniques to pharmaceutical research is a known technique in drug development, representing a predictable application of machine learning to existing medical technologies
Source Patent Element
Method of administering coronavirus treatment compounds
PTD Variation
Incorporating IoT sensors for real-time patient vital sign monitoring during treatment
Obviousness Reasoning
Remote patient monitoring is a well-established medical technology, and integrating sensor technologies with pharmaceutical treatments represents an obvious design choice for improving patient care
Source Patent Element
Coronavirus treatment compounds with potential variable configurations
PTD Variation
Using nanomaterials to enhance compound bioavailability
Obviousness Reasoning
Nanotechnology for drug delivery is a recognized approach in pharmaceutical sciences, representing a finite and predictable solution for improving drug absorption and efficacy
Source Patent Element
Pharmaceutical compound distribution methods
PTD Variation
Implementing blockchain platform for tracking compound distribution and administration
Obviousness Reasoning
Blockchain technology for supply chain and medical record tracking is an emerging but obvious technological solution for improving transparency and traceability in medical systems
Source Patent Element
Coronavirus treatment method using specific compound structures
PTD Variation
Integrating multiple advanced technologies to create a comprehensive treatment ecosystem
Obviousness Reasoning
Systematic technological integration is a standard approach in modern medical research, representing an obvious method of improving treatment protocols through multidisciplinary approaches
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857517 and the disclosed technological variations, a person of ordinary skill in the art would find the proposed combinations of pharmaceutical compounds with advanced digital technologies to be obvious extensions of existing medical treatment methodologies. The incremental technological integrations represent predictable applications of known techniques in pharmaceutical research and digital health platforms, thereby rendering potential patent claims obvious and anticipatable as prior art.

Original Patent Information

Patent NumberUS 11,857,517
TitleCompounds for treating corona virus infection
Assignee(s)NLC Pharma Ltd