Personalized Pain Management Systems with Adaptive Intranasal Lidocaine Delivery

Publication ID: 24-11857520_0010_PTD
Published: October 28, 2025
Category:Future Evolutions & Paradigm Shifts

Legal Citation

pr1or.art Inc., “Personalized Pain Management Systems with Adaptive Intranasal Lidocaine Delivery,” Published Technical Disclosure No. 24-11857520_0010_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857520_0010_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,520.

Summary of the Inventive Concept

A next-generation pain management system integrating wearable devices, AI-powered algorithms, and preservative-free intranasal lidocaine dispensers to provide personalized, adaptive, and real-time pain treatment.

Background and Problem Solved

The original patent disclosed a preservative-free intranasal composition for treating various pain conditions. However, it lacked personalization and adaptability, relying on fixed dosing regimens. The new inventive concept addresses this limitation by introducing wearable devices, AI-driven algorithms, and real-time feedback mechanisms to optimize pain treatment for individual patients.

Detailed Description of the Inventive Concept

The system comprises a wearable device detecting pain patterns, a neural network-based algorithm predicting optimal dosing regimens, and a preservative-free intranasal composition dispenser. The dispenser releases customized doses of lidocaine based on the detected pain patterns, medical histories, and real-time pain feedback. The system can be integrated with mobile applications, cloud-based servers, and biofeedback-controlled transnasal lidocaine delivery systems to provide a comprehensive pain management platform.

Novelty and Inventive Step

The new claims introduce wearable devices, AI-powered algorithms, and real-time feedback mechanisms, which are novel and non-obvious compared to the original patent. These innovations enable personalized, adaptive, and real-time pain treatment, distinguishing the new inventive concept from existing solutions.

Alternative Embodiments and Variations

Alternative embodiments may include using different wearable devices, such as smartwatches or implantable sensors, or integrating the system with other pain management modalities, such as electrical stimulation or pharmacogenomics. Variations may also involve using different AI algorithms or machine learning models to predict optimal dosing regimens.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the pain management market, particularly in the areas of chronic pain, neuropathic pain, and migraines. The system's adaptability and personalization capabilities can improve treatment outcomes, reduce healthcare costs, and enhance patient quality of life. Target industries include pharmaceutical companies, medical device manufacturers, and healthcare providers.

CPC Classifications

SectionClassGroup
A A61 A61K31/167
A A61 A61K9/0043
A A61 A61M11/00
A A61 A61M2210/0618

Field of Art

Medical Device Technology and Pharmaceutical Delivery Systems, specifically focused on intranasal pain management compositions and personalized medical technologies

Person of Ordinary Skill (PHOSITA) Profile

A professional with expertise in pharmaceutical formulation, medical device design, and digital health technologies, holding advanced degrees in biomedical engineering, pharmacology, or related fields, with working knowledge of drug delivery systems and AI-enabled medical technologies

Obviousness Rationale

A PHOSITA would recognize that the PTD represents a predictable technological evolution of the source patent by integrating known digital health monitoring technologies with the existing preservative-free intranasal lidocaine delivery method. The combination of wearable sensing, AI-driven dosing algorithms, and the established intranasal lidocaine composition represents an incremental and obvious technological advancement that applies standard digital health design principles to an existing pharmaceutical delivery approach.

Obvious Combinations & Variations

Source Patent Element
Preservative-free intranasal lidocaine composition for pain management
PTD Variation
Adding wearable device-based pain pattern detection and AI-powered dosing algorithms
Obviousness Reasoning
Integrating sensor technologies with pharmaceutical delivery is a known technique in personalized medicine, representing a predictable application of digital health monitoring to an existing medical treatment method
Source Patent Element
Multi-dose nasal spray pump device delivering 0.04-0.2 ml lidocaine volumes
PTD Variation
Incorporating microcontroller for real-time dosage adjustment based on user feedback
Obviousness Reasoning
Adaptive dosing represents a standard design optimization approach, using embedded computing to modify an existing drug delivery mechanism in a foreseeable manner
Source Patent Element
Treatment of neuropathic and migraine pain conditions
PTD Variation
Adding biofeedback mechanisms like EEG-based pain detection for targeted lidocaine administration
Obviousness Reasoning
Utilizing neurological monitoring for precise pharmaceutical intervention is a known technique in pain management, representing an obvious extension of existing treatment methodologies
Source Patent Element
Intranasal lidocaine composition for targeted pain treatment
PTD Variation
Creating cloud-connected mobile platform for remote pain monitoring and personalized dosing
Obviousness Reasoning
Developing digital health platforms to manage pharmaceutical interventions is a standard technological progression in modern medical device design
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857520 and the disclosed technological variations, a person of ordinary skill in the art would find the claimed innovations obvious and non-patentable, as they represent predictable combinations of known pharmaceutical delivery techniques with standard digital health monitoring technologies, thereby constituting obvious variations that lack inventive conceptualization beyond the existing prior art.

Original Patent Information

Patent NumberUS 11,857,520
TitleTherapeutic composition of intranasal lidocaine
Assignee(s)Nortic Holdings Inc.