AI-Enhanced Anti-Mycobacterial Therapy System

Publication ID: 24-11857521_0003_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “AI-Enhanced Anti-Mycobacterial Therapy System,” Published Technical Disclosure No. 24-11857521_0003_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857521_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,521.

Summary of the Inventive Concept

A novel system integrating oligo(carbamoylated guanidine)s (OCGs) with artificial intelligence (AI), Internet of Things (IoT), blockchain, and machine learning to create a personalized, adaptive, and secure anti-mycobacterial treatment platform.

Background and Problem Solved

The current TB treatment regimen is lengthy and rigorous due to difficulties associated with Mycobacterium tuberculosis (Mtb) resistance. The original patent introduced OCGs as a promising anti-mycobacterial agent, but its efficacy and treatment outcomes can be improved by integrating it with advanced technologies.

Detailed Description of the Inventive Concept

The AI-enhanced system comprises OCGs, AI for personalized medicine, IoT-enabled sensors for real-time monitoring, a blockchain-secured data storage system, and a machine learning algorithm for predicting mycobacterial resistance patterns. The AI optimizes OCG dosages based on patient-specific genomic data, while the IoT sensors track treatment efficacy and adjust dosages accordingly. The blockchain system ensures data integrity and utilizes novel, OCG-resistant materials for storing data. The machine learning algorithm predicts resistance patterns, enabling proactive treatment adjustments.

Novelty and Inventive Step

The new claims introduce a synergistic combination of OCGs with AI, IoT, blockchain, and machine learning, which is not obvious from the original patent. The integration of these distinct technologies creates a novel, more powerful system that addresses the limitations of the original patent.

Alternative Embodiments and Variations

Alternative embodiments may include using different AI algorithms, integrating with other IoT devices, or utilizing alternative blockchain platforms. Variations may include adapting the system for other infectious diseases or incorporating additional technologies, such as nanotechnology or gene editing.

Potential Commercial Applications and Market

The AI-enhanced anti-mycobacterial therapy system has significant commercial potential in the pharmaceutical and healthcare industries, particularly in developing countries where TB is prevalent. The system's ability to provide personalized, adaptive, and secure treatment can improve treatment outcomes, reduce healthcare costs, and enhance patient quality of life.

CPC Classifications

SectionClassGroup
A A61 A61K31/17
A A61 A61K31/133
A A61 A61K31/277
A A61 A61K31/4409
A A61 A61K31/47
A A61 A61K31/496
A A61 A61K31/498
A A61 A61K31/4965
A A61 A61K31/5377
A A61 A61P31/06
C C07 C07C279/12
C C07 C07D295/215
C C08 C08G65/00
C C08 C08G71/02
C C07 C07C2601/16

Original Patent Information

Patent NumberUS 11,857,521
TitleAnti-mycobacterial drugs
Assignee(s)The Florida International University Board of Trustees