Synergistic Anti-Mycobacterial Treatment Systems

Publication ID: 24-11857521_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Anti-Mycobacterial Treatment Systems,” Published Technical Disclosure No. 24-11857521_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857521_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,521.

Summary of the Inventive Concept

The invention integrates oligo(carbamoylated guanidine) (OCG) compounds with distinct technologies, such as AI, IoT, blockchain, and new materials, to create a more powerful system for treating tuberculosis and monitoring treatment outcomes.

Background and Problem Solved

Tuberculosis (TB) is a deadly infectious disease caused by Mycobacterium tuberculosis (Mtb). The current TB treatment regimen is lengthy and rigorous due to difficulties associated with diagnosis, treatment, and patient monitoring. The original patent addressed this issue with OCG compounds, but the new inventive concept takes it a step further by synergistically combining these compounds with other technologies to create a more comprehensive and effective system.

Detailed Description of the Inventive Concept

The new system comprises an OCG-based pharmaceutical composition, an AI-powered diagnostic tool for identifying Mycobacterium tuberculosis strains, an IoT-enabled device for tracking patient response to treatment, and a blockchain-based platform for secure storage and analysis of patient data. The system also includes a novel material for wound dressings, comprising a composite of OCG and a nanofiber matrix, which exhibits synergistic antibacterial and wound-healing properties. Furthermore, the system incorporates an AI-powered predictive model for identifying high-risk TB patients and a blockchain-based platform for tracking TB treatment outcomes.

Novelty and Inventive Step

The new claims introduce a synergistic combination of OCG compounds with AI, IoT, blockchain, and new materials, which is not obvious from the original patent. The integration of these technologies provides a more comprehensive and effective system for treating TB and monitoring treatment outcomes, addressing the limitations of the original patent.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include using different AI algorithms for diagnostic and predictive purposes, incorporating other IoT-enabled devices for patient monitoring, or developing new materials with enhanced antibacterial properties. Variations of the system could also include integrating the OCG-based pharmaceutical composition with other treatment regimens or using the blockchain-based platform for tracking treatment outcomes in other diseases.

Potential Commercial Applications and Market

The synergistic anti-mycobacterial treatment system has significant commercial potential in the pharmaceutical and healthcare industries, particularly in regions with high TB prevalence. The system's ability to provide a more comprehensive and effective treatment approach could lead to improved patient outcomes, reduced healthcare costs, and increased market share for pharmaceutical companies and healthcare providers.

CPC Classifications

SectionClassGroup
A A61 A61K31/17
A A61 A61K31/133
A A61 A61K31/277
A A61 A61K31/4409
A A61 A61K31/47
A A61 A61K31/496
A A61 A61K31/498
A A61 A61K31/4965
A A61 A61K31/5377
A A61 A61P31/06
C C07 C07C279/12
C C07 C07D295/215
C C08 C08G65/00
C C08 C08G71/02
C C07 C07C2601/16

Original Patent Information

Patent NumberUS 11,857,521
TitleAnti-mycobacterial drugs
Assignee(s)The Florida International University Board of Trustees