Tucaresol-based compositions for niche environments and applications

Publication ID: 24-11857522_0004_PTD
Published: October 28, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Tucaresol-based compositions for niche environments and applications,” Published Technical Disclosure No. 24-11857522_0004_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857522_0004_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,522.

Summary of the Inventive Concept

The inventive concept adapts tucaresol-based compositions for specific, high-need environments and applications, such as high-altitude, high-security, disaster relief, and extreme weather conditions, ensuring effective treatment and immune system support in these unique contexts.

Background and Problem Solved

The original patent disclosed tucaresol-based compositions for general cancer treatment. However, these compositions may not be suitable for patients in specialized environments or with specific needs. This inventive concept addresses the limitation by developing tucaresol-based compositions tailored to these niche applications, enhancing treatment outcomes and immune system response in these challenging situations.

Detailed Description of the Inventive Concept

The inventive concept encompasses four specialized variations: (1) a system for treating patients in high-altitude environments, where the composition is adapted to mitigate altitude-related hypoxia; (2) a method for enhancing the efficacy of immune checkpoint inhibitors in patients with compromised immune systems, where the composition is formulated to compensate for immune system deficiencies; (3) a pharmaceutical kit for emergency response situations, designed for use in extreme weather conditions; and (4) a system for treating patients in high-security environments, incorporating security measures to prevent unauthorized access. Each variation leverages the tucaresol-based composition's unique properties to address the specific challenges of its target environment or application.

Novelty and Inventive Step

The inventive concept's novelty lies in its adaptation of tucaresol-based compositions to address specific, high-need environments and applications. The inventive step resides in the tailored formulations and system designs that overcome the limitations of the original patent, ensuring effective treatment and immune system support in these unique contexts.

Alternative Embodiments and Variations

Other possible implementations of the inventive concept include adaptations for space exploration, remote or isolated communities, or specialized medical facilities. Additionally, the composition could be modified to address specific immune system deficiencies or to incorporate additional therapeutic agents.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the pharmaceutical and biotechnology industries, particularly in the areas of cancer treatment, immune system support, and emergency response. The target markets include high-altitude regions, high-security facilities, disaster relief organizations, and specialized medical facilities.

CPC Classifications

SectionClassGroup
A A61 A61K31/192
A A61 A61K31/496
A A61 A61K39/3955
A A61 A61P35/00
C C07 C07K16/2818
C C07 C07K16/2827
A A61 A61K2039/505

Original Patent Information

Patent NumberUS 11,857,522
TitleCompositions containing tucaresol or its analogs
Assignee(s)BeyondSpring Pharmaceuticals, Inc.