Tucaresol-based compositions for niche environments and applications
Legal Citation
Summary of the Inventive Concept
The inventive concept adapts tucaresol-based compositions for specific, high-need environments and applications, such as high-altitude, high-security, disaster relief, and extreme weather conditions, ensuring effective treatment and immune system support in these unique contexts.
Background and Problem Solved
The original patent disclosed tucaresol-based compositions for general cancer treatment. However, these compositions may not be suitable for patients in specialized environments or with specific needs. This inventive concept addresses the limitation by developing tucaresol-based compositions tailored to these niche applications, enhancing treatment outcomes and immune system response in these challenging situations.
Detailed Description of the Inventive Concept
The inventive concept encompasses four specialized variations: (1) a system for treating patients in high-altitude environments, where the composition is adapted to mitigate altitude-related hypoxia; (2) a method for enhancing the efficacy of immune checkpoint inhibitors in patients with compromised immune systems, where the composition is formulated to compensate for immune system deficiencies; (3) a pharmaceutical kit for emergency response situations, designed for use in extreme weather conditions; and (4) a system for treating patients in high-security environments, incorporating security measures to prevent unauthorized access. Each variation leverages the tucaresol-based composition's unique properties to address the specific challenges of its target environment or application.
Novelty and Inventive Step
The inventive concept's novelty lies in its adaptation of tucaresol-based compositions to address specific, high-need environments and applications. The inventive step resides in the tailored formulations and system designs that overcome the limitations of the original patent, ensuring effective treatment and immune system support in these unique contexts.
Alternative Embodiments and Variations
Other possible implementations of the inventive concept include adaptations for space exploration, remote or isolated communities, or specialized medical facilities. Additionally, the composition could be modified to address specific immune system deficiencies or to incorporate additional therapeutic agents.
Potential Commercial Applications and Market
The inventive concept has significant commercial potential in the pharmaceutical and biotechnology industries, particularly in the areas of cancer treatment, immune system support, and emergency response. The target markets include high-altitude regions, high-security facilities, disaster relief organizations, and specialized medical facilities.
CPC Classifications
| Section | Class | Group |
|---|---|---|
| A | A61 | A61K31/192 |
| A | A61 | A61K31/496 |
| A | A61 | A61K39/3955 |
| A | A61 | A61P35/00 |
| C | C07 | C07K16/2818 |
| C | C07 | C07K16/2827 |
| A | A61 | A61K2039/505 |
Section 103 Obviousness Analysis (PHOSITA)
Field of Art
Pharmaceutical chemistry, immunotherapy, and cancer treatment, with expertise in immune checkpoint inhibitors, chemical compound design, and therapeutic composition formulation
Person of Ordinary Skill (PHOSITA) Profile
A researcher with advanced degrees in pharmaceutical sciences or medicinal chemistry, familiar with immunological techniques, drug delivery systems, and molecular modification strategies for therapeutic compounds
Obviousness Rationale
A PHOSITA would recognize that the PTD's variations represent predictable extensions of the source patent's core tucaresol composition and immune checkpoint inhibitor strategy. The disclosed environmental adaptations and specialized delivery systems represent routine optimization techniques well within the ordinary skill of pharmaceutical researchers. The modifications primarily involve standard pharmaceutical engineering approaches to enhance drug efficacy and delivery in specific contexts.
Obvious Combinations & Variations
Original Patent Information
| Patent Number | US 11,857,522 |
|---|---|
| Title | Compositions containing tucaresol or its analogs |
| Assignee(s) | BeyondSpring Pharmaceuticals, Inc. |