Industrial Process Corrosion Inhibition and Pollutant Removal Using Tucaresol Analogs

Publication ID: 24-11857522_0007_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Industrial Process Corrosion Inhibition and Pollutant Removal Using Tucaresol Analogs,” Published Technical Disclosure No. 24-11857522_0007_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857522_0007_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,522.

Summary of the Inventive Concept

The present inventive concept leverages tucaresol and its analogs to address corrosion and pollution challenges in industrial processes, offering a novel solution for industries such as oil and gas, wastewater treatment, and fuel cells.

Background and Problem Solved

The original patent focused on the use of tucaresol and its analogs in pharmaceutical compositions for cancer treatment. However, these compounds also exhibit properties that make them suitable for addressing corrosion and pollution issues in industrial processes. The present inventive concept addresses the limitations of current corrosion inhibitors and pollutant removal methods, which often have environmental and health concerns, or are ineffective in certain applications.

Detailed Description of the Inventive Concept

The inventive concept involves the use of tucaresol and its analogs as corrosion inhibitors in industrial processes, particularly in the oil and gas industry, where they can prevent corrosion of metal surfaces in contact with process fluids such as crude oil or natural gas. Additionally, these compounds can be used to remove heavy metals and other pollutants from wastewater, and as proton conductors in fuel cells, enhancing their efficiency and stability.

Novelty and Inventive Step

The new claims introduce a novel application of tucaresol and its analogs in industrial processes, which is distinct from their original use in pharmaceutical compositions. The inventive concept's use of these compounds as corrosion inhibitors, pollutant removers, and proton conductors represents a non-obvious and innovative solution to the problems addressed.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of tucaresol and its analogs in other industrial processes, such as mining, construction, or manufacturing, where corrosion and pollution are significant concerns. Variations of the inventive concept could also involve the combination of these compounds with other materials or technologies to enhance their effectiveness.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in various industries, including oil and gas, wastewater treatment, and fuel cells. The market for corrosion inhibitors and pollutant removal methods is substantial, and the present inventive concept offers a novel and effective solution that could capture a significant share of this market.

CPC Classifications

SectionClassGroup
A A61 A61K31/192
A A61 A61K31/496
A A61 A61K39/3955
A A61 A61P35/00
C C07 C07K16/2818
C C07 C07K16/2827
A A61 A61K2039/505

Field of Art

Chemical engineering and materials science, with expertise in organic chemistry, pharmaceutical compositions, and industrial process technologies. Skill level includes advanced understanding of molecular design, chemical transformations, and cross-domain applications of organic compounds

Person of Ordinary Skill (PHOSITA) Profile

A researcher or engineer with advanced degree in chemistry, capable of understanding molecular structure-function relationships, familiar with chemical modification strategies, and experienced in translating pharmaceutical compounds to industrial applications

Obviousness Rationale

A PHOSITA would recognize that tucaresol's molecular structure suggests versatile applications beyond pharmaceutical uses. The compound's chemical properties inherently support potential industrial applications like corrosion inhibition and pollutant removal. The source patent's broad structural claims implicitly suggest potential alternative uses through routine experimentation and molecular adaptation.

Obvious Combinations & Variations

Source Patent Element
Tucaresol analog with specific substituent groups (Y1, Y2, Y3, Y4)
PTD Variation
Using identical molecular structure as corrosion inhibitor in industrial processes
Obviousness Reasoning
Predictable extension of known molecular properties, demonstrating alternative functional utility through standard chemical engineering design principles
Source Patent Element
Pharmaceutical composition with immune checkpoint modulation
PTD Variation
Applying similar molecular framework for proton conductivity in fuel cell technologies
Obviousness Reasoning
Known technique of repurposing pharmaceutical compounds for materials science applications, representing a finite set of predictable technological adaptations
Source Patent Element
Chemical compound with potential interaction capabilities
PTD Variation
Utilizing molecular structure for heavy metal sequestration in wastewater treatment
Obviousness Reasoning
Routine scientific exploration of molecular binding properties, representing an obvious technological extension through standard chemical engineering problem-solving
Source Patent Element
Compound with substituent groups allowing chemical modifications
PTD Variation
Combining tucaresol analog with oxidizing agents for enhanced pollutant removal
Obviousness Reasoning
Predictable chemical combination strategy using known interaction principles, representing a standard approach to enhancing chemical performance
35 U.S.C. § 103 Summary: Based on US Patent 11857522's comprehensive molecular disclosure, the present publication demonstrates that a person having ordinary skill in the art would find the industrial process applications of tucaresol analogs obvious through routine scientific exploration. The structural similarities, predictable chemical behaviors, and established cross-domain technology transfer principles render the claimed variations prima facie obvious under 35 U.S.C. ยง 103.

Original Patent Information

Patent NumberUS 11,857,522
TitleCompositions containing tucaresol or its analogs
Assignee(s)BeyondSpring Pharmaceuticals, Inc.