Synergistic Cancer Treatment Systems

Publication ID: 24-11857522_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Cancer Treatment Systems,” Published Technical Disclosure No. 24-11857522_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857522_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,522.

Summary of the Inventive Concept

The present invention relates to novel systems for treating cancer by combining pharmaceutical compositions containing tucaresol or its analogs with distinct technologies, such as AI, IoT, blockchain, and new materials, to create a more powerful and effective treatment approach.

Background and Problem Solved

The original patent disclosed pharmaceutical compositions containing tucaresol or its analogs for treating cancer. However, the patent did not provide a comprehensive solution for tracking patient responses, analyzing genomic data, or optimizing treatment regimens. The present invention addresses these limitations by integrating the patented compositions with other distinct technologies to create a more holistic treatment approach.

Detailed Description of the Inventive Concept

The new inventive concept comprises systems and methods for treating cancer that integrate pharmaceutical compositions containing tucaresol or its analogs with AI, IoT, blockchain, and new materials. For example, a system may include a blockchain-based data management platform for tracking patient responses to the composition, an AI-powered analysis of a patient's genomic data to personalize treatment, or an IoT device for monitoring patient vital signs. The inventive concept enables a more targeted, efficient, and effective treatment approach by leveraging the strengths of each technology.

Novelty and Inventive Step

The new claims introduce a novel combination of the patented pharmaceutical compositions with distinct technologies, such as AI, IoT, blockchain, and new materials. This integration provides a non-obvious solution to the limitations of the original patent, as it enables a more comprehensive and effective treatment approach.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept may include integrating the pharmaceutical compositions with other technologies, such as robotics, nanotechnology, or 3D printing. Variations of the inventive concept may also include using different types of cancer or different patient populations.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the cancer treatment market, particularly in the areas of personalized medicine, precision oncology, and digital health. The target industries include pharmaceutical companies, healthcare providers, and medical technology companies.

CPC Classifications

SectionClassGroup
A A61 A61K31/192
A A61 A61K31/496
A A61 A61K39/3955
A A61 A61P35/00
C C07 C07K16/2818
C C07 C07K16/2827
A A61 A61K2039/505

Field of Art

Pharmaceutical oncology and immunotherapy, with expertise in cancer treatment compositions, immune checkpoint inhibitors, and computational healthcare technologies

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degrees in pharmaceutical sciences, oncology, or biomedical engineering, possessing knowledge of cancer immunotherapies, computational methods, and interdisciplinary medical technologies

Obviousness Rationale

A PHOSITA would recognize that integrating digital technologies with pharmaceutical compositions represents a natural progression in personalized medicine. The source patent's focus on tucaresol and immune checkpoint inhibitors provides a clear foundation for exploring technological augmentations to treatment protocols. The disclosed variations demonstrate predictable combinations of known technologies that enhance treatment monitoring, personalization, and efficacy tracking.

Obvious Combinations & Variations

Source Patent Element
Pharmaceutical composition containing tucaresol with immune checkpoint inhibitors
PTD Variation
Blockchain-based data management platform for tracking patient treatment responses
Obviousness Reasoning
Implementing digital tracking systems for medical treatments is a known technique in healthcare informatics, with predictable results of improved patient monitoring and data management
Source Patent Element
Immune checkpoint inhibitor combinations for cancer treatment
PTD Variation
AI-powered genomic data analysis for personalized treatment selection
Obviousness Reasoning
Precision medicine approaches using computational analysis of patient genomic data represent a standard evolutionary approach in oncology treatment optimization
Source Patent Element
Cancer treatment composition with multiple therapeutic components
PTD Variation
IoT wearable devices for continuous patient vital sign monitoring during treatment
Obviousness Reasoning
Integration of remote patient monitoring technologies is a predictable extension of existing medical treatment protocols, offering enhanced patient management
Source Patent Element
Pharmaceutical composition targeting immune system responses
PTD Variation
Machine learning platforms for predicting treatment outcomes based on medical history
Obviousness Reasoning
Computational prediction of medical treatment efficacy is a well-established technique in clinical research, representing an obvious technological enhancement
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857522 and the Published Technical Disclosure, a person having ordinary skill in the art would find the disclosed technological augmentations to cancer treatment compositions obvious and predictable. The combination of pharmaceutical compositions with digital tracking, AI analysis, and IoT monitoring represents a natural progression in personalized medical technologies, rendering potential claims covering such integrations obvious and non-patentable under 35 U.S.C. Section 103.

Original Patent Information

Patent NumberUS 11,857,522
TitleCompositions containing tucaresol or its analogs
Assignee(s)BeyondSpring Pharmaceuticals, Inc.