Synergistic Cholestatic Disease Management System

Publication ID: 24-11857523_0003_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Cholestatic Disease Management System,” Published Technical Disclosure No. 24-11857523_0003_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857523_0003_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,523.

Summary of the Inventive Concept

A novel system integrating elafibranor treatment with AI, IoT, blockchain, and new materials to provide personalized, data-driven management of cholestatic diseases

Background and Problem Solved

The original patent addressed the treatment of cholestatic diseases, specifically PBC and PSC, with elafibranor. However, it did not provide a comprehensive solution for monitoring, predicting, and adapting to disease progression. The new inventive concept addresses this limitation by incorporating distinct technologies to create a more powerful system

Detailed Description of the Inventive Concept

The system comprises a wearable device for tracking patient biomarkers, an AI-powered analytics module for predicting disease progression, and a personalized treatment planner integrating elafibranor administration with lifestyle recommendations. Additionally, the system incorporates machine learning algorithms for optimizing elafibranor treatment, a blockchain-based platform for secure data management, a smart pillbox system for ensuring patient adherence, and a novel biomaterial composition for oral delivery of elafibranor

Novelty and Inventive Step

The new claims introduce a synergistic combination of distinct technologies, providing a holistic approach to cholestatic disease management. The inventive step lies in the integration of these technologies to create a more effective and personalized treatment system

Alternative Embodiments and Variations

Alternative embodiments could include different AI algorithms, various wearable devices, or alternative blockchain platforms. Variations could also include integrating the system with electronic health records or telemedicine platforms

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the pharmaceutical and healthcare industries, particularly in the areas of personalized medicine, digital health, and disease management

CPC Classifications

SectionClassGroup
A A61 A61K31/192
A A61 A61K45/06
A A61 A61P37/06

Original Patent Information

Patent NumberUS 11,857,523
TitleMethods of treatment of cholestatic diseases
Assignee(s)Genfit