Specialized Treatment Solutions for Cholestatic Diseases in Unique Environments

Publication ID: 24-11857523_0004_PTD
Published: October 28, 2025
Category:Specialized Variations & Niche Solutions

Legal Citation

pr1or.art Inc., “Specialized Treatment Solutions for Cholestatic Diseases in Unique Environments,” Published Technical Disclosure No. 24-11857523_0004_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857523_0004_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,523.

Summary of the Inventive Concept

Adapting elafibranor-based treatment methods for cholestatic diseases to cater to specific, high-need populations and operational environments, such as high-security settings, disaster relief situations, extreme weather conditions, remote areas, and high-altitude environments.

Background and Problem Solved

The original patent disclosed methods for treating cholestatic diseases, particularly PBC and PSC, using elafibranor. However, these methods may not be directly applicable to unique environments, where additional challenges and constraints exist. The present inventive concept addresses these limitations by developing specialized treatment solutions tailored to these niche scenarios.

Detailed Description of the Inventive Concept

The new inventive concept comprises a range of solutions, including secure, tamper-proof containers for high-security environments; compositions formulated for use in disaster relief settings; portable, weather-resistant devices for extreme weather conditions; satellite communication systems for remote, isolated areas; and formulations adapted for high-altitude environments. These solutions incorporate elafibranor as the active pharmaceutical ingredient, ensuring effective treatment of cholestatic diseases in these unique environments.

Novelty and Inventive Step

The new claims introduce novel, non-obvious variations of the original patent's methods, specifically designed to address the challenges and constraints of high-security, disaster relief, extreme weather, remote, and high-altitude environments. These specialized solutions provide a significant improvement over existing treatments, offering enhanced accessibility, security, and efficacy in these niche scenarios.

Alternative Embodiments and Variations

Alternative embodiments may include the use of different pharmaceutical ingredients, varying formulations, or alternative communication devices. Variations could also involve integrating these solutions with existing infrastructure, such as medical facilities or emergency response systems, to enhance their effectiveness.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in various industries, including pharmaceuticals, medical devices, and emergency response services. Target markets include government agencies, disaster relief organizations, and medical providers operating in high-security, remote, or extreme environments.

CPC Classifications

SectionClassGroup
A A61 A61K31/192
A A61 A61K45/06
A A61 A61P37/06

Original Patent Information

Patent NumberUS 11,857,523
TitleMethods of treatment of cholestatic diseases
Assignee(s)Genfit