Synergistic Cholestatic Disease Treatment Systems

Publication ID: 24-11857523_0008_PTD
Published: October 28, 2025
Category:Synergistic Combinations

Legal Citation

pr1or.art Inc., “Synergistic Cholestatic Disease Treatment Systems,” Published Technical Disclosure No. 24-11857523_0008_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857523_0008_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,523.

Summary of the Inventive Concept

The present inventive concept integrates the patented methods of treating cholestatic diseases with cutting-edge technologies such as AI, IoT, blockchain, and genomics analysis to create a more effective, personalized, and secure treatment system.

Background and Problem Solved

The original patent disclosed methods for treating cholestatic diseases, specifically PBC and PSC. However, these methods have limitations in terms of patient data management, treatment efficacy prediction, and personalized treatment plans. The new inventive concept addresses these limitations by leveraging synergistic combinations of technologies to create a more comprehensive and effective treatment system.

Detailed Description of the Inventive Concept

The new inventive concept comprises a blockchain-based patient data management platform, machine learning algorithms for predicting treatment efficacy, AI-powered genomics analysis software, IoT-enabled sensors for tracking biomarkers, and cloud-based data analytics platforms for identifying trends and patterns. These components work together to provide personalized treatment plans, optimize treatment options, and ensure secure and transparent storage of patient data. The system can be integrated with wearable devices for monitoring patient symptoms, and electronic health records can be securely stored on a blockchain-based platform.

Novelty and Inventive Step

The new claims introduce a novel combination of technologies that creates a more powerful and effective treatment system for cholestatic diseases. The integration of AI, IoT, blockchain, and genomics analysis with the patented methods of treating cholestatic diseases provides a non-obvious and innovative solution that addresses the limitations of the original patent.

Alternative Embodiments and Variations

Alternative embodiments of the inventive concept could include the use of different machine learning algorithms, varying IoT sensor configurations, or alternative blockchain platforms. Additionally, the system could be adapted for use in treating other diseases or conditions, or integrated with other healthcare technologies such as telemedicine platforms or medical imaging devices.

Potential Commercial Applications and Market

The synergistic cholestatic disease treatment system has significant commercial potential in the healthcare industry, particularly in the areas of personalized medicine, disease management, and healthcare data analytics. The system could be marketed to healthcare providers, pharmaceutical companies, and medical research institutions, and could potentially disrupt the current treatment paradigm for cholestatic diseases.

CPC Classifications

SectionClassGroup
A A61 A61K31/192
A A61 A61K45/06
A A61 A61P37/06

Original Patent Information

Patent NumberUS 11,857,523
TitleMethods of treatment of cholestatic diseases
Assignee(s)Genfit