Baclofen-based Solutions for Environmental Sustainability

Publication ID: 24-11857524_0002_PTD
Published: October 28, 2025
Category:New Applications & Use Cases

Legal Citation

pr1or.art Inc., “Baclofen-based Solutions for Environmental Sustainability,” Published Technical Disclosure No. 24-11857524_0002_PTD, Published October 28, 2025, available at https://archive.pr1or.art/24-11857524_0002_PTD
This technical disclosure describes improvements that would be readily apparent to a Person Having Ordinary Skill In The Art (PHOSITA) when considered in combination with the foundational architecture disclosed in U.S. Patent No. 11,857,524.

Summary of the Inventive Concept

This inventive concept leverages the core technology of stable oral suspensions of baclofen to develop novel applications in environmental sustainability, including treating aquatic life, reducing algae growth, enhancing bioremediation, improving soil quality, and reducing pesticide use in agriculture.

Background and Problem Solved

The original patent focused on stable oral suspensions of baclofen for human pharmaceutical use, but the limitations of the patent did not explore the potential of baclofen in environmental sustainability. This inventive concept addresses the need for innovative solutions in environmental conservation, specifically in aquatic ecosystems, soil quality, and bioremediation.

Detailed Description of the Inventive Concept

The inventive concept involves applying the stable oral suspension of baclofen to various environmental applications. In aquatic life treatment, the suspension reduces stress and anxiety in aquatic organisms. In algae growth reduction, the baclofen inhibits algae growth in aquatic environments. In bioremediation, the suspension enhances the degradation of pollutants. In soil quality improvement, the suspension increases the growth of beneficial microorganisms. Finally, in reducing pesticide use, the suspension increases the natural resistance of crops to pests. The common thread among these applications is the use of baclofen as a key component, leveraging its therapeutic properties to achieve environmental benefits.

Novelty and Inventive Step

The new claims introduce a paradigm shift in the application of baclofen, moving from human pharmaceutical use to environmental sustainability. The inventive concept combines the core technology of stable oral suspensions of baclofen with novel environmental applications, resulting in a non-obvious and innovative solution.

Alternative Embodiments and Variations

Alternative embodiments could include using different concentrations of baclofen, varying the pH range of the suspension, or incorporating additional components to enhance the environmental benefits. Variations could also involve applying the inventive concept to other environmental areas, such as air pollution remediation or waste management.

Potential Commercial Applications and Market

The inventive concept has significant commercial potential in the environmental sustainability market, with potential applications in aquatic ecosystems, agriculture, and bioremediation. The market for environmental sustainability solutions is growing rapidly, driven by increasing concerns about climate change and ecosystem degradation. The inventive concept could be licensed to companies operating in these industries, providing a new revenue stream for ANI Pharmaceuticals, Inc.

Field of Art

Pharmaceutical formulations and environmental applications, with expertise in drug suspension technologies, pharmacological compound manipulation, and environmental treatment methods

Person of Ordinary Skill (PHOSITA) Profile

A professional with advanced degrees in pharmaceutical sciences, chemistry, or environmental engineering, possessing knowledge of drug formulation techniques, suspension stability, and interdisciplinary applications of pharmaceutical compounds

Obviousness Rationale

A PHOSITA would recognize that the stable oral suspension technology of baclofen disclosed in the source patent provides a versatile platform for exploring alternative applications beyond human pharmaceutical use. The fundamental properties of the baclofen suspension - stability, controlled concentration, and adaptable pH range - inherently suggest potential for broader environmental interventions. The PTD's environmental applications represent predictable extensions of the core suspension technology by leveraging known pharmacological properties of baclofen in novel contextual domains.

Obvious Combinations & Variations

Source Patent Element
Stable liquid suspension of baclofen with concentration of 2 mg/mL or more
PTD Variation
Applying baclofen suspension to aquatic life stress reduction and environmental treatments
Obviousness Reasoning
A PHOSITA would recognize that the stable suspension formulation enables controlled delivery across different environmental contexts, representing a predictable application of known pharmaceutical suspension technology
Source Patent Element
Pharmaceutically acceptable excipients including pH adjusting agents and buffering components
PTD Variation
Modifying suspension pH and composition for environmental sustainability applications
Obviousness Reasoning
The source patent's flexible formulation approach inherently suggests adaptability for different environmental treatment scenarios, making such variations a matter of routine engineering design
Source Patent Element
Aqueous suspension with pH range between 4 to 8
PTD Variation
Utilizing suspension's pH characteristics for bioremediation and soil microorganism enhancement
Obviousness Reasoning
The established pH stability of the baclofen suspension directly implies potential for environmental microbiological interactions, representing an obvious extension of the original pharmaceutical formulation
Source Patent Element
Stable liquid pharmaceutical composition suitable for oral administration
PTD Variation
Repurposing suspension technology for environmental stress reduction and pollutant degradation
Obviousness Reasoning
A PHOSITA would recognize that the core suspension technology's stability and controlled delivery mechanism naturally suggests broader applications beyond initial pharmaceutical intent
Source Patent Element
Baclofen as a therapeutically effective compound
PTD Variation
Exploring baclofen's potential for pest resistance and agricultural applications
Obviousness Reasoning
The known pharmacological properties of baclofen, combined with the stable suspension technology, would suggest potential interactions with biological systems beyond human therapeutics
35 U.S.C. § 103 Summary: Based on the teachings of US Patent 11857524 and the disclosed variations, a person of ordinary skill in the art would find the environmental applications of stable baclofen suspensions to be obvious extensions of the existing pharmaceutical formulation technology. The predictable combination of known suspension characteristics with novel application domains renders potential claims in this space anticipated and non-patentable under standard obviousness analysis.

Original Patent Information

Patent NumberUS 11,857,524
TitleStable oral suspensions of baclofen
Assignee(s)ANI Pharmaceuticals, Inc.